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May 18 โ€ข 4 tweets โ€ข 2 min read โ€ข Read on X
๐™ƒ๐™ค๐™ฌ ๐™ฉ๐™ค ๐™š๐™จ๐™ฉ๐™ž๐™ข๐™–๐™ฉ๐™š ๐™–๐™ž๐™ง๐™—๐™ค๐™ง๐™ฃ๐™š ๐™Ž๐˜ผ๐™๐™Ž-๐˜พ๐™Š๐™‘-2 ๐™ฉ๐™ง๐™–๐™ฃ๐™จ๐™ข๐™ž๐™จ๐™จ๐™ž๐™ค๐™ฃ ๐™ž๐™ฃ ๐™™๐™–๐™ฎ๐™˜๐™–๐™ง๐™š ๐™ง๐™ค๐™ค๐™ข๐™จ ? Image
2) This study estimated hourly airborne SARS-CoV-2 transmission risk in daycare rooms by calculating inhaled viral doses from occupancy, activities, and aerosol emission/transport models. Risks significantly varied by room and time ... cell.com/heliyon/fullteโ€ฆ
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3) ... with changing rooms and lunchrooms having the highest risks. Sensitivity analysis found viral shedding rates and infectious doses to be key uncertainties. While absolute risks are uncertain, the method effectively identified higher-risk spaces and ... Image
4) ...times to guide mitigation measures like ventilation and occupancy limits.

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More from @ejustin46

May 20
๐—ง๐—ต๐—ฒ ๐—ต๐˜‚๐—บ๐—ฎ๐—ป ๐—ฐ๐—ผ๐˜€๐˜ ๐—ผ๐—ณ "๐—Ÿ๐—˜๐—ง ๐—œ๐—ง ๐—ฅ๐—œ๐—ฃ" !

academic.oup.com/eurpub/advanceโ€ฆ
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2) Rather than a summary, this time we decided to post a very interesting extract from this study:
"Although analyses of potential reasons for the country-wise differences in mortality each pandemic year is beyond the scope of this article, one could speculate ... Image
3) ...that different responses may have had an impact.ย Furthermore, the estimates may have been influenced by a mortality displacement, attributed to abnormally low pre-pandemic mortality in Sweden in 2019 and the rigorous countermeasures in the other three countries... Image
Read 7 tweets
May 20
๐—” ๐—ฃ๐—”๐—ก๐——๐—˜๐— ๐—œ๐—– ๐—ถ๐˜€ ๐—›๐—˜๐—ง๐—˜๐—ฅ๐—ข๐—š๐—˜๐—ก๐—˜๐—ข๐—จ๐—ฆ !

Different groups or areas may experience different levels of infection rates, mortality rates, transmission dynamics, and health outcomes. nature.com/articles/s4146โ€ฆ
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2) This heterogeneity refers to the variation or diversity in the impact, spread, and severity of the disease across different populations, regions, or individuals. It is influenced by various factors such as population demographics, healthcare infrastructure ... Image
3) ...socioeconomic conditions, access to healthcare, public health measures, and individual behaviors.
Pandemics involve complex interactions between biological, social, economic, and environmental factors.
Let's avoid excessive simplifications ! Image
Read 6 tweets
May 20
๐—–๐—ฒ๐—ฟ๐—ฒ๐—ฏ๐—ฟ๐—ฎ๐—น ๐—บ๐—ถ๐—ฐ๐—ฟ๐—ผ๐˜€๐˜๐—ฟ๐˜‚๐—ฐ๐˜๐˜‚๐—ฟ๐—ฎ๐—น ๐—ฎ๐—น๐˜๐—ฒ๐—ฟ๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€ ๐—ถ๐—ป ๐—ฃ๐—ผ๐˜€๐˜-๐—–๐—ข๐—ฉ๐—œ๐——-๐—ฐ๐—ผ๐—ป๐—ฑ๐—ถ๐˜๐—ถ๐—ผ๐—ป
H/t @bhanlon15 @mryoung151
nature.com/articles/s4146โ€ฆ
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2) Cerebral microstructure was investigated in 89 patients with Post-COVID Condition per WHO criteria, 38 with past COVID but no lasting issues, and 46 healthy controls using diffusion magnetic resonance imaging. Patients with PCC showed a shift in gray matter ...
3) ...from the extra-neurite volume fraction, representing the cellular compartment and extracellular matrix, to the free fluid volume fraction compared to the other groups. Voxel-wise analyses found PCC associated with reduced extra-neurite in neocortical regions ... Image
Read 5 tweets
May 19
๐—œ๐— ๐— ๐—จ๐—ก๐—˜ ๐—œ๐— ๐—ฃ๐—ฅ๐—œ๐—ก๐—ง๐—œ๐—ก๐—š
๐—›๐—ผ๐˜‚๐˜€๐˜๐—ผ๐—ป, ๐˜„๐—ฒ ๐—ต๐—ฎ๐˜ƒ๐—ฒ ๐—ฎ ๐—ฝ๐—ฟ๐—ผ๐—ฏ๐—น๐—ฒ๐—บ ? ๐Ÿค”

(3๐˜ณ๐˜ฅ ๐˜ด๐˜ต๐˜ถ๐˜ฅ๐˜บ ๐˜ช๐˜ฏ 1 ๐˜ธ๐˜ฆ๐˜ฆ๐˜ฌ ๐˜ฐ๐˜ฏ ๐˜ต๐˜ฉ๐˜ช๐˜ด ๐˜ต๐˜ฐ๐˜ฑ๐˜ช๐˜ค, 6๐˜ต๐˜ฉ ๐˜ด๐˜ต๐˜ถ๐˜ฅ๐˜บ ๐˜ด๐˜ช๐˜ฏ๐˜ค๐˜ฆ ๐˜ต๐˜ฉ๐˜ฆ ๐˜ฃ๐˜ฆ๐˜จ๐˜ช๐˜ฏ๐˜ฏ๐˜ช๐˜ฏ๐˜จ ๐˜ฐ๐˜ง ๐˜ต๐˜ฉ๐˜ฆ ๐˜บ๐˜ฆ๐˜ข๐˜ณ !)
nature.com/articles/s4146โ€ฆ
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2) The study evaluated the immunogenicity of bivalent mRNA booster vaccines containing the Omicron BA.1 or BA.5 spike protein against the background of different primary vaccination regimens (mRNA-based or adenovirus vector-based).
3) 434 healthcare workers who received either an adenovirus or mRNA primary vaccine series participated. They were randomized to receive either a BA.1 or BA.5 bivalent booster vaccine Image
Read 10 tweets
May 19
๐— ๐—ข๐—•๐—œ๐—Ÿ๐—œ๐—ง๐—ฌ ๐—ถ๐˜€ ๐˜๐—ต๐—ฒ ๐—บ๐—ฎ๐—ถ๐—ป ๐—ง๐—ฅ๐—œ๐—š๐—š๐—˜๐—ฅ ๐—ณ๐—ผ๐—ฟ ๐˜๐—ต๐—ฒ ๐—ง๐—ฅ๐—”๐—ก๐—ฆ๐— ๐—œ๐—ฆ๐—ฆ๐—œ๐—ข๐—ก ๐—ข๐—™ ๐—–๐—ข๐—ฉ๐—œ๐——-19 ๐—ฎ๐—ป๐—ฑ ๐—ผ๐˜๐—ต๐—ฒ๐—ฟ ๐—ฟ๐—ฒ๐˜€๐—ฝ๐—ถ๐—ฟ๐—ฎ๐˜๐—ผ๐—ฟ๐˜† ๐˜ƒ๐—ถ๐—ฟ๐˜‚๐˜€๐—ฒ๐˜€ ! Image
2) Even if we regret the use of the word "post-pandemic", it remains a very interesting and key study.
Researchers examined the impacts of human mobility and behavior on the transmission of 18 respiratory viruses (including SARS-CoV-2) in the Seattle area from 2018-2022. Image
3) Mobility data came from mobile device locations, while virus incidence was estimated from extensive hospital and community respiratory surveillance.
Prior to the pandemic, trends in many endemic virus transmissions correlated with mobility indicators like visits to schools .. Image
Read 8 tweets
May 19
๐—ช๐—ต๐—ฎ๐˜ ๐—ถ๐˜€ ๐—ฐ๐˜‚๐—ฟ๐—ฟ๐—ฒ๐—ป๐˜ ๐—ฐ๐—ฎ๐—ฟ๐—ฒ ๐—ณ๐—ผ๐—ฟ ๐—ฝ๐—ฒ๐—ผ๐—ฝ๐—น๐—ฒ ๐˜„๐—ถ๐˜๐—ต ๐—Ÿ๐—ผ๐—ป๐—ด ๐—–๐—ข๐—ฉ๐—œ๐—— ๐—ถ๐—ป ๐—˜๐—ป๐—ด๐—น๐—ฎ๐—ป๐—ฑ?

bmjopen.bmj.com/content/14/5/eโ€ฆ
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2) This qualitative study explored care for Long COVID in England through interviews with 21 patients and 15 healthcare professionals. Key themes included the complex physical/mental symptoms experienced by patients and highlighted challenges accessing primary care. Image
3) While post-COVID-19 services provided validation and expertise, early uncertainty resulted in varied care approaches. Image
Read 4 tweets

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