Thread by @ejustin46

𝘾𝙤𝙜𝙣𝙞𝙩𝙞𝙫𝙚 𝙙𝙮𝙨𝙛𝙪𝙣𝙘𝙩𝙞𝙤𝙣𝙨 𝙞𝙣 𝙩𝙝𝙚 𝙘𝙤𝙪𝙧𝙨𝙚 𝙤𝙛 𝙎𝘼𝙍𝙎‑𝘾𝙤𝙑‑2 𝙫𝙞𝙧𝙪𝙨 𝙞𝙣𝙛𝙚𝙘𝙩𝙞𝙤𝙣, 𝙞𝙣𝙘𝙡𝙪𝙙𝙞𝙣𝙜 𝙉𝙚𝙪𝙧𝙤𝘾𝙊𝙑𝙄𝘿, 𝙛𝙧𝙤𝙣𝙩𝙖𝙡 𝙨𝙮𝙣𝙙𝙧𝙤𝙢𝙚 𝙖𝙣𝙙 𝙘𝙮𝙩𝙤𝙠𝙞𝙣𝙚 𝙨𝙩𝙤𝙧𝙢

𝘙𝘦𝘷𝘪𝘦𝘸
spandidos-publications.com/10.3892/br.202…

2) COVID-19 impacts cognitive functioning through several pathways. The virus may directly infect brain cells or enter the central nervous system indirectly.
A major driver of cognitive effects is the cytokine storm - when the immune system overreacts and releases ...

3) ... too many inflammatory proteins.
This neuroinflammation can disrupt brain cell communication and survival. Cytokines like IL-6 are particularly implicated.
The cytokine storm may also weaken the blood-brain barrier, allowing more viruses to enter the brain.

4) This exacerbates neuroinflammation and neuronal death. Specific brain regions like the hippocampus seem especially vulnerable.
Some patients develop conditions like NeuroCOVID and frontal syndrome during the acute phase.

5) Symptoms involve problems with short-term memory, executive function, and attention. Severity often correlates with blood marker levels of inflammation.
Long COVID can yield prolonged psychiatric effects due to chronic stress and neuroinflammation.

6) This may worsen pre-existing neurological disorders or increase risk of conditions like Alzheimer's. Early diagnosis and treatments seeking to dampen inflammation may help mitigate cognitive consequences.

Thanks for reading 🙏