Hi 👋🏻 I seem to have gained a few new followers lately. So a brief introduction seems due!
I’m a research scientist with a specialist topic in companion animal behaviour & welfare, skills in veterinary epidemiology & psychometric tool development.
I’m also chronically ill ♿️
I’ve been chronically ill with #MyalgicEncephalomyelitus since a virus destroyed my health aged 15. I also recently learned I have #POTS too.
I’m a patient-expert in ME and my body reacted so badly to my Covid vaccines that my ME is now Severe. I cannot work & am housebound.
I need a wheelchair on the rare occasions I can leave the house, but cannot push myself etc so I rely on my spouse as my carer.
I can stand and walk very short distances so I am what’s called an ambulatory wheelchair user.
I am ‘woke’ and liberal, and I try to be a good ally to LGBTQ+ communities. I am also neurodivergent.
I tweet mostly about ME now as trying to navigate my Severe ME has taken over everything for me.
I also tweet about Long Covid and sometimes my dog 🐶 plants 🪴 & flowers 🌷
I am not well enough to get into debates or arguments. I simply don’t have the energy anymore to waste like that. If you try to debate me, I will likely just Mute you for my own wellbeing.
I block when needed for this reason too. Twitter is where I find community, not anger.
If all that is ok with you, then welcome and thanks for following!
Here’s a rose from my garden for your timeline.
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“Our results demonstrate that pantethine, which is well tolerated in humans, was very effective in controlling SARS-CoV-2 infection and might represent a new therapeutic drug that can be repurposed for the prevention or treatment of COVID-19 & long COVID” nature.com/articles/s4159…
“cellular expression of the viral spike and nucleocapsid proteins was substantially reduced, and we observed a significant reduction in viral copy numbers in the supernatant of cells treated with pantethine”
Pantethine is thought to have antiviral actions because it reduces cholesterol levels. Viruses, especially SARS-CoV-2 use cholesterol to replicate and infect our cells.
The body often dramatically reduces cholesterol production in response to viral infection for this reason.
There are sometimes meds or supplements that make people feel worse at first. Sometimes.
These usually will be known about & predictable, as they work by breaking biofilms or can trigger deficiencies in other things when one deficiency is addressed (B12 is a good example).
In some cases, the worsening is a sign that what you’re doing is needed.
But there’s *huge* caveats here.
Some ppl are so severe, they can’t risk any slight worsening.
Some worsening’s are not safe or expected & should never be pushed through.
How do you tell which it is?
You need careful supervision and extensive knowledge of the pathways you are affecting to be able to know how to attempt to address a worsening, even when it is a sign you’re in the right path.
99% don’t have that and they should *not* push through worsening on their own.
I can’t read the papers in detail unfortunately, but from what I did read, supplementing Tyrosine is not expected to increase adrenaline or dopamine production - unless you’re depleted already.
So, it’s considered useful to supplement under high stress conditions only.
However, we do know that in #POTS (and maybe other dysautonomia and MCAS) people’s bodies release adrenaline (norepinephrine) simply when upright, to help blood vessels contract.
Maybe useful for us? May improve cognitive function?
Seriously, get it in your cupboard and if it’s ok for you to take (I haven’t found any proven interactions though), use it for Covid prevention or when infected
200-400mg of 95% OPC extract reduces viral load & stops the virus from replicating by 50%
Other very strict laboratory studies of extreme bed rest (beyond what most people ever experience) show that the metabolic consequences of it do not trigger anything like the diseased state we see in ME or Long Covid.
The presenters are, I’m afraid, showing their ignorance.
They also failed to read or acknowledge the actual exercise science on people with ME & Long Covid that shows a distinct abnormal pathology in response to exercise in these patients. A pathology not seen in any other disease. Again, highlighting their lack of expertise @ACSMNews