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Lazarus Long Profile picture
@LazarusLong13
Jul 10, 2024 • 21 tweets • 10 min read • Read on X
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This study is HUGE FOR YOU!

Why? Every hospital, dental, and nursing home corporation around the world use studies designed by the Mark Loeb Group to keep N95s off of your HCW.

As they bend over you in a mask so baggy you can see their toothy smile.

Let me ask you...

/1
Would pulling on an N95 protect you more from airborne anthrax than if you pulled on a medical mask (MM)? From only 3 feet away?

In fact, IT IS AGAINST the proper use of respirators.

OSHA would have you KICKED off the job site.

But when Loeb did it in 2022? The $$$ 🎉🎉🎉
But - once this preprint is published? I do not see how Loeb (2022) is not RETRACTED.🔥🔥🔥

That study compared surgical masks to N95s. It said that surgical (medical) masks are as good as N95s in protection from Covid.

That they are not inferior, aka noninferior, to N95s.
And this stone-cold evisceration of the Loeb group who richly deserve it?

Is a thing of savage beauty.

Starting with - how do you not get infected 3 feet away from some feverish (febrile) C0Vid infected?

(Plus, the 58% asymptomatic transmissions? )
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But Loeb's group said, "No way, man. Our people were rolling strapped! From the parking lot to the parking lot." (Universal masking***).

Now, this is where it gets good.

Someone👇 confirmed with a Loeb study member that the N95 group could use medical masks in hallways.
Post-hoc assertions that the trial was carried out with all subjects in the N95 arm wearing their PPE continuously are unsupported by evidence: The claim is not supported by prospectively registered information;(65–67) The claim is not consistent with the initial study protocol;(64) The study ended March 29th, 2022, yet the modified statistical analysis plan dated February 17th, 2022 and the modified protocol dated March 1st 2022(64) both specify that subgroup analyses would include sites with and without universal masking; Despite being fundamental to the interpretation of the trial result...
Dr. Lynora Saxinger MD FRCPC Infectious Diseases @AntibioticDoc · Dec 2, 2022 **So it’s all gotten a bit leggy but if you are entering here I did confirm and need to clarify continuous masking didn’t have to be assigned mask so N95 group could use medical masks in hallways etc so is not a “all shift” N95 which is what I’d understood from a studymember
And the people in medical masks could wear N95s anytime they wanted.

Got it? This supposedly very methodological study has people switching anytime they wanted. Participants in the MM arm were allowed to wear N95 at any time based on point of care risk assessment.(58) Considering that the most COVID-cautious participants would have had both the greatest motivation to report and seek treatment for suspected infection; and to take advantage of the opportunity to wear N95 if assigned to the MM arm, it would be expected that these factors would interact to further artefactually reduce cases recorded in the MM arm.
And their OWN PLAN said they would have sites with and without universal masking.

Until they changed it after the fact.

AFTER THE FACT! Can we trust them? Surely they have no incentive to lie like rugs, right?

No UNREPORTED conflicts of interests like 7 million dead.

The claim is not consistent with the initial study protocol;(64) The study ended March 29th, 2022, yet the modified statistical analysis plan dated February 17th, 2022 and the modified protocol dated March 1st 2022(64) both specify that subgroup analyses would include sites with and without universal masking;
As noted above, the trial was explicitly designed around an inappropriate intermittent-use protocol – a fatal flaw from which unregistered protocol modifications and coincidental universal use are claimed to have salvaged it. Retroactive insertion into the registry with back-dating to the beginning of the trial (a repudiation of the purpose of trial registration) does not provide the evidence such claims require.
Unreported conflicts of interest As discussed above, COVID is known to be substantially airborne, transmitted in infectious bioaerosols.(3) Anticipated in the earliest days of the pandemic, this danger was overlooked by policy makers at great cost(2) - a “…very big mistake” where better decisions “…would have saved an enormous number of lives”.(116) Seven million deaths have now been officially attributed directly to COVID, with the real total estimated at 27 million(117) and possibly much higher,(118) and millions more suffer long-term impacts from Post Covid Condition (PCC).(119–123) Any ...
No conflicts of interest at all, like 16 study members running IPC at their hospital. No pressure from needing to be proved right. No pressure to keep costs low as N95s are spendy!

None like testifying at a trial to deny nurses N95s. With 5 study members.
Sixteen of the authors as well as two of the three members of the Data Safety and Monitoring Board (DSMB) hold Medical Director of Infection Control (MDIC) or similar positions at their respective institutions (Table 1). Of these, nine (including the DSMB Chair) are located in the province of Ontario, where in 2021 the Ontario Nurses’ Association requested judicial review of hospital infection control policies they asserted were dangerously inadequate in failing to provide for universal use of N95 respirators.(100,127) Similar positions regarding SARS-CoV-2 mitigations had been taken nation...
Endorsed shortly before the end of data collection for the Loeb trial in Canada, the affidavit also included the statement: “…our experience at my hospital and other healthcare facilities throughout Canada where use of medical mask and eye protection alone to care for an unmasked patient with unrecognized COVID- 19, has not resulted in transmission to healthcare workers.”(127) It is unclear how the members of the DSMB reconciled endorsing this statement as accurate with the then-current trial data they were responsible for being aware of, showing multiple infections in healthcare workers we...
None like running THE group that the WORLD listened to for a year of death. Or being a member. Senior author Dr. Conly chairs the WHO Infection Prevention and Control Research and Development Expert Group for COVID-19 (WHO-C19-EG – of which Dr. Loeb was also a member),(131) upon whose advice the WHO’s position on COVID prevention was largely based in the first year of the pandemic.(132) This group had publicly argued against the need to adopt “…the precautionary principle with consequent use of particulate respirators instead of medical masks as a component of PPE for routine care of COVID- 19 patients…” in August 2020,(125) despite previously receiving direct warnings to the contrar...
No, when the study was abruptly moved from Canada to Egypt, Israel, Pakistan, just as clear evidence was emerging that N95s were better than MM? Nothing suspicious.

And Egypt ending up being the location for finding surgical masks are the same as N95s?
When the study was terminated at all sites in the prospectively registered countries, the results showed clear evidence of a result opposite to the primary published finding, showing medical masks very likely provided substantially reduced protection against a pathogen with potential to cause death or serious harm.
The reported finding of noninferiority is entirely an artefact of the data from sites in Egypt, and cannot be obtained without them even if we were to accept all other alterations to the trial as legitimate.
Nothing against Egypt, it's just where serious issues with women being forced to work, men in N95s, bad ventilation, public transportation in the middle of the first Omicron wave, all caused that effect.

Although... The omission of site information from the published information and the trial registry is particularly relevant in Egypt, as only one of the six sites was equipped with an HVAC system (in contrast to 100% of sites elsewhere, per Supplement Table 11),(58) with the other five provided only with “…a combination of air conditioning and outdoor air”. Without further information this could mean simply openable windows and some recirculating air conditioners, which would tend to encourage closing of the windows while providing essentially no air cleaning – the worst combination possible in the pre...
The actual data collected was sketch AF. "Perfectly excluded" is not a good phrase to hear about your study.

You been busted, son! Is a rough translation. The pattern observed in the data reported by Loeb and colleagues appears highly unlikely (p<0.006) to occur naturally in data collected as described in the publication.
Nothing like a few changes to a study👇. Between 16 IPC directors, you'd think they'd kick all kinds of study a$$, instead of needing midstream changes.

There is more, but I am tired of reading about the Canadian IPC Mafia.

They are very bad people who did a very bad study. Image
That should be retracted!

They did it! Called for retraction!



/Continued with some thoughts. acpjournals.org/doi/full/10.73…
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Actual care exposure time to patients in Egypt was about double (very important, not mentioned)?

It has all the outbreaks (mentioned in the study)
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One factor everyone seems to have missed? Maybe I just didn't see it?

Extended use AND re-use of the N95s does not seem to have been factored in.

Fit failure is a huge issue.👇

Loeb does a self-own on this in commenting on his own study.
healthresearch.healthsci.mcmaster.ca/surgical-masks…



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Universal masking was not fully explained in the study.

Parking lot to parking lot?

UM in Egypt, Pakistan, Canada - might be all different.

For example, Japan, this hospital had universal masking, but not in break rooms. Led to infections.
ncbi.nlm.nih.gov/pmc/articles/P…
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Pakistani where PATIENTS did not adhere to universal masking (UM), despite beng requird to.

Obviously, patients are aerosol src. Also, the antimaskers at the Loeb group included ACH at the various places. THAT IS NOT MEASURED ACH. There is a
researchgate.net/profile/Saerah…
huge difference - if you ask someone actually experienced with aerosols.

Changing rooms in hospitals - we have no idea of the Egypt set up.


We do know Egyptian HCWs are pretty good at masking up at work. Not in public.
journals.lww.com/joem/fulltext/…
ijic.info/article/view/2…

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Loeb (2022), truly one of the worst studies ever. Giving Walach a run for his money.
My apologies, I forgot to link to the top of the thread for your convenience!

Thank you for getting to here and now knowing how the latest masking RCT is fatally flawed.

The other two main ones are also flawed in the main same way. 3 feet.

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More from @LazarusLong13

Lazarus Long Profile picture
Dec 21
Oh, we are cooked. Just cooked.

"Brain Mitochondrial dysfunction, known for ~20 years is finally recognized as a central upstream driver of Alzheimer’s disease (AD), not just a downstream effect."

And SARS2's targeting of mitochondria is well-known.

Even in the brain.
/1 We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease. Our work, combining multiple experimental and analytical methods, demonstrates the brain-wide impact of severe acute/subacute COVID-19, involving both cortical and subcortical regions, shedding light on potential therapeutic targets within pat...
@LauraMiers, in case you don't have it.

nature.com/articles/s4358…
@LauraMiers This is yet another reason why I N95.

Read 6 tweets
Lazarus Long Profile picture
Dec 17
@neiljshaw - — a few tips on your excellent article from a clean air advocate

"Consider Wearing a Mask" ?

No, "It is incredibly important to wear a well-fitting mask such as a N95, KN95, or KF94, for the best protection."

You two are doing Image
public health with this article.

Public health is best done with simple clear instructions.

No:
"These masks act as a barrier, reducing the spread of respiratory droplets when people talk, sneeze or cough."

Yes:
"These masks act as a HEPA air cleaner for the face,
cleaning the air of respiratory aerosols when people breathe, talk, sneeze or cough."

The barrier carries the idea of an immovable wall. Unable to be penetrated by things like oxygen and CO2 - which feeds antimaskers.

As an who debunks antimaskers, it is
Read 9 tweets
Lazarus Long Profile picture
Dec 11
As an anonymous clean air advocate, I've put a bit of thought into how to present, well, my expertise.

If someone were to say, "How do I know you know what you are talking about? Are you a doctor, or a virologist?"

To which, I would say...."No, but that's a good thing.
/1
I have focused on aerosol and masking science. Because it is those fields that give us the most information on how airborne particles, aerosols, get from Person A to Person B.

My expertise is derived from the great studies of Dr. Lindsay Marr, MacArthur recipient. Dr. Prather,
double National Academy member, Dr Milton, inventor of the Gesundheit, aerosol scientist and medical doctor; Dr Coleman whose group found that duckbill N95s captured 98% of emitted respiratory aerosols, and more excellent individual aerosol scientists.
Read 17 tweets
Lazarus Long Profile picture
Nov 22
I am not a fan of nasal sprays to stop The 'Vid, but I respect you having it as a layer in the Swiss cheese package.

But, some people have said they got bloody noses.

While at the ER yesterday, I picked up a pretty good at home technique. Let our $1,000 lay-out
Image
save you money.

Use tongue depressors to make a nose pinch clamp.

Leave it on for 30 minutes. Still a problem? Two sprays of Afrin, and re-apply nose pinch clamp. Wait 30 minutes.

Still a problem? Cotton balls sprayed with Afrin, clamp, 30 minutes

aliem.com/trick-of-trade…Image
Image
Image
Afrin- in generic form is $3.32 at Walmart.

Also, put a ice compress at the back of the neck, while doing the above.

"Cooling the nape of the neck is said to induce reflex constriction of the mucosal vessels of the nose"

✅ I agree with the authors.

pubmed.ncbi.nlm.nih.gov/1568881/Image
Image
Read 6 tweets
Lazarus Long Profile picture
Nov 13
A study demonstrated 100% PERFECT protection against SARS2 w/ readily available KF94s

✅ 181 HCWs
✅ 1 got SARS2 antibodies, but an epi investigation -> the infection happened elsewhere.
😡 The final checkpoint was March 2021. N95s only became freely available 1 month later
/1 FDA: N95 masks, now plentiful, should no longer be reused By MARTHA MENDOZA and JULIET LINDERMAN (Associated Press) April 23, 2021 12:44 p.m. Medical providers may soon return to using one medical N95 mask per patient, a practice that was suspended during the pandemic due to deadly supply shortages
What is described in the tweets
in the USA.

Korean study:
jkms.org/DOIx.php?id=10…

This is in comparison to a Swiss study during the same rough time-frame. A study which did NOT show the same excellent results, but dismal results. Why?

The Swiss had the same sort of fit testing,

pubmed.ncbi.nlm.nih.gov/35123572/ Results: We enrolled 3259 participants from nine healthcare institutions, whereof 716 (22%) preferentially used FFP2. Among these, 81/716 (11%) reported a SARS-CoV-2-positive swab, compared to 352/2543 (14%) surgical mask users; seroconversion was documented in 85/656 (13%) FFP2 and 426/2255 (19%) surgical mask users. Adjusted for baseline characteristics, COVID-19 exposure, and risk behaviour, FFP2 use was non-significantly associated with decreased risk for SARS-CoV-2-positive swab (adjusted hazard ratio [aHR] 0.8, 95% CI 0.6-1.0) and seroconversion (adjusted odds ratio [aOR] 0.7, 95% CI ...
PPE monitoring.

What was the big difference?

Are N95s/FFP2s inferior to KF94s?

No, it was supply - and other reasons.
Read 10 tweets
Lazarus Long Profile picture
Nov 5
@tomhanks has just been savaged by people screaming masks don't work.

All hospitals have fiduciary responsibilities to not waste money.

Here is a light sampling of hospitals mandating masks because they work.

Proving that not only do masks work, but mask mandates work.

Thread
Health PEI
Start/End: October 14, 2025 , How many hospitals: 7, employee count: 4,967,

Public hospital,

City: Various (e.g., Charlottetown, Summerside), Province: Prince Edward Island, Country: Canada, full url: princeedwardisland.ca/en/news/health…
Horizon Health Network
Start/End: September 3, 2025 How many hospitals: 12, employee count: 15,000, public or private:

Public hospital.

City: Various (e.g., Saint John, Fredericton),
Province: New Brunswick,
Country: Canada horizonnb.ca/coronavirus-co…
Read 32 tweets

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