Joe Pierre, MD Profile picture
Jul 10 10 tweets 2 min read Read on X
1/ Practicing medicine involves a relationship between physician and patient. Psychiatry even moreso due to the focus on symptoms and internal experiences as opposed to objective/external signs which ironically is a frequent criticism of the field from a diagnostic standpoint.
2/ The perspectives of doctors, patients, and families are distinct. One is not necessarily more "deep" than another and each contributes something, reminiscent of the parable of the blind men and the elephant.
3/ Sometimes those perspectives--whether physician, patient, and/or family--are distorted. Certainly in psychiatry, it's recognized that cognitive distortions and delusions can be a challenge.
4/ Whether in formal psychotherapy or not, there should be collaborative work (patient informs physician and physician informs patient) towards understanding and potentially seeing things in a different light.
5/ Physicians do indeed spend countless hours with patients. Due to the intimate nature of what's discussed (again, even moreso in psychiatry), it can often amount to substantially more time spent discussing issues than what's shared with any other person.
6/ The claim that a "medical degree" doesn't add to an understanding of mental health/illness ignores that time spent "sitting" w/ patients. Despite related claims re: the so-called "biomedical" approach, that's not really how MDs, and esp. not psychiatrists, approach patients.
7/ An oncologist doesn't only bring to the table expertise about the biology of cancer cells. She brings the experience of being with patients who have suffered its effects and the families who have mourned their death.
8/ Conversely, a psychiatrist doesn't only bring experience sitting with patients. She brings her own lived experience with mental health issues. She brings her knowledge of the therapeutic and adverse effects of medications as well as the many "medical" causes of mental illness.
9/ That experience--rather than a medical degree per se--is indeed a form of "authority" and "expertise." It may not be the be-all-and-end-all, but in terms of making a difference, it's something and in some cases everything.
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More from @psychunseen

Feb 26, 2023
1/ C’mon people… put down your cognitive bias and motivated reasoning!

This new DOE report on the LaB Leak hypothesis doesn’t disclose ANY evidence and proves absolutely NOTHING.

Read what WSJ article actually says...

wsj.com/articles/covid…
2/ Not clear why the Dept of Energy is looking into this anyway, but theirs is a minority opinion among the 6 other intelligence agencies who have opined on the subject.

Most others say Lab Leak unlikely.
3/ Meanwhile, DOE opinion is made with LOW CONFIDENCE.

Not high, not medium, but LOW.
Read 6 tweets
Feb 3, 2023
1/ Oh boy... So @MSN is legitimizing this @dcexaminer piece claiming that masks don't work to spread COVID as if it's news. It's not news!

It's an OP-ED piece written by a conservative columnist.

msn.com/en-us/health/m…
2/ The op-ed author cites a new @CochraneLibrary meta-analysis of 78 randomized controlled trials (RCTs)—describing it as a "massive mega-study"—to claim that masks don't stop the spread of COVID-19.

But the analysis only included 6 RCTs that involved COVID-19! Not massive!
3/ The analysis looked at several interventions other than masks... leaving only 12 studies that looked at surgical masks (w/ only 2/12 involving COVID) and 5 looked at N95s (none of which involved COVID)!

Now, it's true that the effect of surgical masks vs. no masks was weak...
Read 16 tweets
Jan 31, 2023
1/ I'm a firm believer in the heterogeneity of "mental disorders." While DSM constructs have clinical utility, most DSM disorders are not "one thing" and don't claim to be.
2/ Like Bleuler's "group of schizophrenias," mental disorders are wastebasket categories that likely represent many different biopsychosocial pathways to a given constellation of symptoms.

pubmed.ncbi.nlm.nih.gov/21505113/
3/ A century ago, people with tertiary syphilis were diagnosed as having schizophrenia.

With the discovery of T. pallidum, we no longer consider neurosyphilis to be a psychiatric disorder, assuming it's detected.

pubmed.ncbi.nlm.nih.gov/30176838/
Read 11 tweets
Oct 11, 2022
1/ Here are FDA approved medications for bipolar disorder as of 2022.

(thanks @eturnermd1 & @ScottMyers20 for inspiring me to update the list)

A few thoughts to bear in mind... Image
2/ Note that some of the oldest & most commonly used meds (e.g. divalproex) don't have FDA approval for maintenance Rx much less BP depression.

That doesn't always mean they aren't effective; sometimes it means they weren't extensively studied prior to (or after) going generic.
3/ When it comes to maintenance, several medications have approvals based on specific formulations (e.g. RIS LAI or QTP XR for BP maintenance) which probably doesn't matter while others are only approved for adjunctive treatment (i.e. added to lithium or divalproex) which does.
Read 7 tweets
Jul 31, 2022
1/ Like many stories in medicine, antidepressant effects were first discovered inadvertently. When people suffering from major depression improved after taking them, scientists then tried to figure out why.

pubmed.ncbi.nlm.nih.gov/19442174/
2/ And so, the monoamine theory was born out of the observed efficacy of MAOIs and TCAs. Prozac was developed more deliberately as a serotonergic drug, but this was done more to reduce the side effect burden of ADs than based on any premise of a serotonergic theory of depression.
3/ The lower side effects of SSRIs (similar to the 2nd generation antipsychotics) drastically changed the landscape of how antidepressants are prescribed, lowering the threshold to prescribe them and broadening the range of patients who are on them.
Read 19 tweets
Jul 30, 2022
1/ This isn't new, but anti-science and anti-psychiatry conspiracy theories are being increasingly embraced by the Right.

rollingstone.com/culture/cultur…
2/ For at least the past few years, the Right has been trying to shift the mass shooting conversation away from guns and on to psychiatric medications.

psychologytoday.com/au/blog/psych-…
3/ After I wrote the above piece following the Charleston church mass shooting in 2015, I was invited to "On Point with Tomi Lahren" to talk about gun violence and psychiatric meds.
Read 14 tweets

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