Emmanuel Profile picture
Jul 19 5 tweets 2 min read Read on X
LESSON from the COVID-19 pandemic: TODDLERS LEARN EARLIER to READ EMOTIONS with FACE MASKS

frontiersin.org/journals/psych…
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2) In this study, researchers found that toddlers aged 3-5 years old showed improved ability to recognize emotions from facial expressions with masks, approaching the performance of adults.
While adults maintained a higher overall accuracy, the impact of masks on ... Image
3) ... emotion inference was similar for both age groups. This suggests that the developing brain's plasticity enabled young children to adapt and learn to utilize alternative cues to infer emotions mitigating the initial challenges posed by the limited visual information ... Image
4) ... from partially occluded faces. The findings provide a positive outlook on the potential for children to overcome the social challenges associated with the widespread use of face masks during a critical period of emotional and social development. Image
5) Thanks for reading 🙏
FYI @DavidJoffe64 @jlerollblues @_CatintheHat @MeetJess @1goodtern

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More from @ejustin46

Jul 21
SARS-COV-2, The CELLS KILLER
(apoptosis, necroptosis, pyroptosis, ferroptosis, and NETosis)
🧵 mega-thread

Picture : Apoptotic cell (pink) heavily infected with SARS-COV-2 virus particles (green), isolated from a patient sample. Image
Read 9 tweets
Jul 20
WHAT a STRANGE IDEA to think that immunity against SARS-CoV-2, would solely rely on a single protein, known as the Spike, and only be dependent on the functionality of neutralizing antibodies ! 🤔

Throughout the course of the pandemic, the Spike protein has dominated ... Image
2) ... the spotlight, whether it be in the context of vaccination or its mutations that enable the virus and its variants to evade the effects of antibodies.

Cursed are those who had the audacity to mention the complexity of the immune response against SARS-CoV-2 ... Image
3) ..with a virus which has 29 proteins, with an immune system which, recognizes over 1400 epitopes, including those found on various proteins, and responds also through the activation of interferons, cytokines, T cells, and other immune cells such as macrophages. Image
Read 6 tweets
Jul 20
WEEKEND FIGURES

The T cell immune response against SARS-CoV-2.

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2) Early and strong immune responses, including interferon and adaptive immunity, are crucial for controlling primary SARS-CoV-2 infection. Delayed or weak responses lead to elevated cellular activation, inflammation, and poor clinical outcomes. Image
3) Memory T cell responses are maintained for up to 12 months after infection clearance. CD4+ and CD8+ T cells, representing a small fraction of the immune repertoire, target numerous epitopes. CD4+ T cells recognize at least 19 epitopes, while CD8+ T cells target 17 epitopes. Image
Read 5 tweets
Jul 19
Soon a TREATMENT for LONG COVID ?

One of the most important studies on this subject 💯💥
🙏 @DavidJoffe64

(AI generated image resized) science.org/doi/10.1126/sc…
Image
2) Allow me first of all, to quickly introduce what IFN-γ is.

IFN-γ is a key protein involved in the immune response against SARS-CoV-2. During the initial infection, IFN-γ helps activate immune cells like T cells and macrophages to fight the virus and clear the infection. Image
3) However, in some people, the body continues to produce high levels of IFN-γ even after the virus has been cleared. This persistent IFN-γ signaling is problematic, causes inflammation leading to long-term breathing difficulties and other respiratory symptoms. Image
Read 8 tweets
Jul 19
Long-COVID OLFACTORY DYSFUNCTION: ALLELE E4 of apolipoprotein E as a POSSIBLE PROTECTIVE FACTOR

thieme-connect.de/products/ejour…
Image
2) This study looked at the relationship between smell dysfunction and a gene called apolipoprotein E (APOE) in patients with long-term COVID-19 symptoms. They found that patients with persistent smell problems were younger and less likely to have been hospitalized ...
3) ...during their initial COVID-19 infection. Interestingly, these patients also had a lower frequency of the APOE E4 gene, which has been linked to more severe COVID-19 cases. The researchers suggest the E4 gene may actually protect against smell dysfunction in ...
Read 4 tweets
Jul 19
EVERYONE can be AFFECTED by long COVID, even ATHLETES

Of the 32 PASC patients in this study, 10 (31%) reported a complete inability to engage in any cardiovascular endurance exercise at 3 months.

Credit : The Guardian onlinelibrary.wiley.com/doi/10.1002/pu…
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2) This study quantified the impact of post-acute sequelae of COVID-19 (PASC) on endurance athletes. 32 of 45 recruited athletes met PASC criteria. The PASC group reported more symptoms at 3 months, including fatigue, shortness of breath, and chest pain. Image
3) They exercised fewer hours and had a 27% decrease in self-reported endurance, with 31% unable to exercise at all. PASC athletes also scored worse on validated questionnaires assessing exercise problems, dyspnea, and quality of life. Image
Read 4 tweets

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