Emmanuel Profile picture
Jul 20, 2024 6 tweets 3 min read Read on X
WHAT a STRANGE IDEA to think that immunity against SARS-CoV-2, would solely rely on a single protein, known as the Spike, and only be dependent on the functionality of neutralizing antibodies ! 🤔

Throughout the course of the pandemic, the Spike protein has dominated ... Image
2) ... the spotlight, whether it be in the context of vaccination or its mutations that enable the virus and its variants to evade the effects of antibodies.

Cursed are those who had the audacity to mention the complexity of the immune response against SARS-CoV-2 ... Image
3) ..with a virus which has 29 proteins, with an immune system which, recognizes over 1400 epitopes, including those found on various proteins, and responds also through the activation of interferons, cytokines, T cells, and other immune cells such as macrophages. Image
4) At the onset of each wave, the "experts" inform us that a single protein, the Spike, along with sometimes just one mutation, that evaded antibodies, could be sufficient to initiate a new wave.

Those who questioned this official stance of the "expert community" ...
5) ... faced criticism, obstruction, or chose to depart from X, much like many of my friends.
I will persist in my fight and will continue to share studies that highlight the intricate nature of the immune system, its vulnerabilities over time ... Image
6) ... and above all, the significant influence of individual behavior in the onset of waves.

Thanks for reading 🙏
FYI @DavidJoffe64 @jlerollblues @michael_hoerger @C_A_G0101

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More from @ejustin46

Jul 28
The SARS-CoV-2 PUZZLE :
How Our Microbes Shape the Disease Picture ?

New technology called next-generation sequencing (NGS) shows that many germs can be present at the same time, affecting how diseases show up in people. Image
2) Instead of thinking one disease is caused by one germ, researchers now consider that multiple active germs can be involved, especially in illnesses like COVID-19.
The germs living in our bodies may play a role in how diseases develop. Image
3) This article looks at how these germs interact with viruses like Influenza and SARS-CoV-2. Changes in the types of germs present can affect the immune response and overall severity of the disease. Image
Read 6 tweets
Jul 24
10 MOST DANGEROUS VIRUSES ON EARTH
(🧵 mega-thread)

1. **SARS-CoV-2**: The virus responsible for COVID-19, notable for its high transmissibility, global impact, and potential for severe illness and long-term health effects. Image
2. **Ebola Virus**: Known for its high mortality rate and severe symptoms, transmitted through direct contact with bodily fluids.
3. **Marburg Virus**: Similar to Ebola, with a high mortality rate and severe disease, transmitted through bodily fluids.
Read 10 tweets
Jul 24
WHY SARS-CoV-2 REMAINS the MOST DANGEROUS VIRUS of ALL TIME ?
(🧵 mega-thread)
2) SARS-CoV-2 is considered one of the most dangerous viruses based on the following criteria:

**Transmission Rate**: SARS-CoV-2 has a high transmission rate, with an R0 value that allows it to spread rapidly within populations.
3) **Infectiousness**: A significant number of infected individuals can transmit the virus to others, including asymptomatic carriers.
Read 13 tweets
Apr 29
Why is Identifying "Non-Trivial SARS-CoV-2 Population Structure within Hosts" Important for Understanding SARS-COV-2 Evolution and the Emergence of New Variants?

journals.plos.org/plospathogens/…Image
2) The "non-trivial population structure" refers to the viral population within a host consisting of two or more distinct, independently evolving subpopulations, rather than a single, homogeneous population. Image
3) The key points about non-trivial population structure are:
▶️ It was relatively common, found in 5 out of the 9 chronic SARS-CoV-2 infection cases examined.
▶️ It was more prevalent in severely immunocompromised individuals compared to those not significantly immunocompromised Image
Read 7 tweets
Apr 26
No, Omicron is not the "humanized" SARS-COV-2 !

(Explanation in simple terms)
biorxiv.org/content/10.110…Image
2) Viruses are not living things. They are tiny particles that can only make copies of themselves inside the cells of living things, like humans. When a virus makes copies of itself, it doesn't always make perfect copies.
3) Sometimes, little mistakes happen, and the new virus has a small change, or mutation, in its genes.

Most of the time, these mutations don't do anything useful for the virus. But every now and then, a mutation might happen that makes the virus better at infecting people. Image
Read 7 tweets
Apr 26
"What if humans had sent SARS-COV-2 into space, or even brought COVID-19 along for astronauts?"

biorxiv.org/content/10.110…Image
2) This study looks at the risks of COVID-19 for people traveling to space.

Space travel is becoming more common, with over 600 people having gone to space. But COVID-19 could be a big problem for astronauts in the unique environment of space. Image
3) The study aims to understand how COVID-19 might behave differently in space compared to on Earth.

The researchers reviewed studies on other airborne diseases in space. They found that some diseases, like Epstein-Barr virus and Serratia bacteria ... Image
Read 6 tweets

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