Emmanuel Profile picture
Jul 29 4 tweets 2 min read Read on X
Even MILD COVID-19 INFECTIONS can have LONG-TERM NEGATIVE EFFECTS on the CARDIOVASCULAR HEALTH of college STUDENTS !

bmcinfectdis.biomedcentral.com/articles/10.11…
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2) The researchers discovered that 2-5 months after infection, the students showed impaired blood vessel function, increased arterial stiffness, and higher blood pressure compared to before they got COVID-19. Image
3) Interestingly, the study also showed that while arterial stiffness improved over time, blood pressure continued to rise, suggesting COVID-19 may have lasting impacts on the cardiovascular system. These findings highlight the importance of monitoring the heart health ... Image
4) ...of COVID-19 survivors, even young and otherwise healthy individuals. The study underscores the need to better understand the long-term cardiovascular consequences of COVID-19 infection.

Thanks for reading 🙏 Image

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More from @ejustin46

Jul 31
BAD NEWS 🥵

➡️ SARS-CoV-2 infection DAMAGES CELLS
➡️ DAMAGED CELLS RELEASE CELL-FREE DNA (cfDNA)
➡️ HIGH LEVELS of cfDNA have severe HARMFUL EFFECTS, as inflammation, organ damage, blood clot formation, immune dysregulation...
nature.com/articles/s4159…
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2) Before to summarize shortly this study, some explanations:

When cells are injured or die, they can release genetic material as cell-free DNA (cfDNA), including cell-free nuclear DNA (cf-nDNA) and cell-free mitochondrial DNA (cf-mtDNA) into the bloodstream. Image
3) These cf-nDNA found in severe COVID-19 patients have several harmful effects on the body:

- Inflammation: When cf-nDNA is released into the bloodstream, it can act as a "damage-associated molecular pattern" (DAMP). This means it signals to the immune system ...
Read 8 tweets
Jul 31
ORIGIN of SARS-COV-2 🤔

"The results indicated that SARS-CoV-2 emerged in FEBRUARY 2019 or EARLIER and evolved into three main haplotypes (GL, DS, and DL) before May 2019, which then continued to evolve in parallel. sciencedirect.com/science/articl…
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2) The dominant haplotype GL had spread worldwide in the summer (May to July) of 2019 and then evolved into virulent strains in December 2019 that triggered the global pandemic."

The origin of SARS-CoV-2 remains a mystery. By analyzing non-redundant SARS-CoV-2 genomes ... Image
3) ...this study found that the virus emerged in February 2019 or earlier and evolved into three main haplotypes (GL, DS, and DL) before May 2019, which then continued to evolve in parallel. The dominant haplotype GL had spread worldwide by summer 2019 and ... Image
Read 6 tweets
Jul 31
Efficacy of traditional Chinese medicine on shortening the negative conversion time of SARS-CoV-2 ribonucleic acid in patients with mild COVID-19

A retrospective cohort study : 6120 laboratory-confirmed patients with mild COVID-19
sciencedirect.com/science/articl…
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2) This study found that using more traditional Chinese medicine (TCM) can help patients with mild COVID-19 recover faster. Patients who received more intensive TCM treatment had the SARS-CoV-2 virus cleared from their body sooner and ... Image
3) ... were discharged from the hospital faster than those who received less TCM. The results suggest TCM could be a useful addition to COVID-19 treatment, but larger studies are still needed to confirm its benefits.

Thanks for reading 🙏 Image
Read 4 tweets
Jul 31
YESTERDAY or TOMORROW ?

"Repeated plague infections across six generations of Neolithic Farmers" 💯

Thanks @jlerollblues
nature.com/articles/s4158…
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2) This study found that plague was widespread in Scandinavia 5,000 years ago, infecting at least 17% of the population. They identified 3 different plague strains that spread through a large family group over about 120 years. Image
3) The earliest strain was less harmful, while a later one may have been more deadly. The researchers also uncovered the social structure, showing a patrilineal society where women married into the community. Image
Read 4 tweets
Jul 31
SARS-COV-2.
COMMON or UNIQUE MUTATIONS between
BATS, DEERS and HUMANS
biorxiv.org/content/10.110…

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2) The researchers developed a new method called PORT-EK that can identify parts of the SARS-CoV-2 virus genome that are more common in certain animal hosts compared to humans.
Using this method, they found:
- Lots of unique DNA sequences (called k-mers) ... Image
3) ...that were more common in deer and bat viruses compared to human viruses. This suggests the virus adapts differently in these animal hosts.
- In the bat viruses, they found 148 mutations in the virus genome. Image
Read 6 tweets
Jul 30
SARS-COV-2 EVERYWHERE !

"The virus is indifferent to whether its host walks on two legs or four"
Carla Finkielstein, PhD
nature.com/articles/s4146…
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2) The study found that SARS-CoV-2 has widely infected various wild animals like deer mice, opossums, and raccoons. They detected the virus's genetic material and antibodies in these species. Image
3) Areas with more human activity had higher infection rates in wildlife, suggesting these areas facilitate virus spread between humans and animals. Genetic sequencing showed the virus jumped from humans to wildlife multiple times. Image
Read 4 tweets

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