Expect 2 more weeks of very high and stable transmission before the summer wave accelerates.
Currently at an estimated 850,000 daily infections, 1 in 56 Americans contagious, 43,000 resulting Long COVID cases/day.
Deep Dive:
Over the next two weeks, we should see very high and stable transmission, before transmission increases rapidly. Note that transmission estimates are down marginally – of no practical impact – relative to last week. One might be tempted to consider that the summer wave is subsiding. That might be a 5-10% probability.
This is where the model gets interesting. The forecasts are derived from a combination of recent patterns in transmission (levels, change, rate of change, rate of rate of change) as well as historical medians for that date. If only using the recent patterns, a decline in the wave would be reasonable.
However, the historic data capture all of that useful information on variation in human behavior (back to school, end of summer vacations, flights, Labor Day) that focusing only on recent patterns would miss. Because behavioral patterns also fuel viral evolution, these historical data also get, to some extent, at the idea of viral evolution of new variants, which we do not track directly in the model.
When considering the forecast, view it two ways. One, based on current trends and historic data, this is what we would expect. Two, if human behavior defied historic trends, we could see something much different, such as a wave subsiding if everyone were more cautious than average this year, or unfortunately something slightly worse than predicted due to the decline in public health guidance on mitigation.
According to the composite forecasting model, that means hovering between 700,000 to 1,050,000 infections/day over the next month. Transmission is very high, and we may reach a later-summer peak of 1.1-1.3 daily infections around September 11.
Although the forecast is for steady transmission over the next two weeks, the forecast is volatile due to quality issues with incoming data.
Schools, medical facilities, and businesses should now escalate precautions and prepare for the disruption of a high percentage of the population getting sick through the remainder of 2024.
You can find the full PMC COVID-19 dashboard and weekly report for Aug 2, 2024 online.
In the report, I have included a link to the PPT slides from yesterday's Space on the new JAMA-NO #KeepMasksInHealthcare article.
The PMC website includes an international directory of websites with COVlD wastewater monitoring. It is more up to date than the directories of the EU and WHO.
Let's review what's happening in Europe...
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Data in #Austria show a rising COVlD wave. The x axis (bottom) has infrequent labels, but the data shown go through October 8th.
An estimated 1 in 81 people are actively infectious during the ongoing 11th wave.
The "shutdown" has created a blackout at the state level.
Transmission is half that of the peak one month ago, and we anticipate a relative national "lull" in early-to-mid November, albeit still at dangerous levels.
Our model uses a combination of CDC and Biobot data, so we are able to estimate national statistics despite the CDC data going offline. On the map, note that Puerto Rico continues to update; they use a CDC-style system but were dropped by the CDC long ago. For full methodology, review the technical appendix on the website.
PMC COVlD Update, Week of Oct 6, 2025 (U.S.)
🧵2/9
#DuringCOVID is today. We estimate >600,000 new daily infections. This is about half the peak on September 6.
Notice current levels are similar to the estimated peaks of the first 3 waves.
PMC COVlD Update, Week of Oct 6, 2025 (U.S.)
🧵3/9
Weekly estimates:
🔹4.5 million infections
🔹>200,000 resulting long-term health conditions
🔹>1,300 resulting excess deaths
Key points in my letter to the pharmacy boards. 🧵1/7
Georgia law indicates that the pharmacy board is to follow ACIP. They do not dictate further nuance. Georgia continues to require prescriptions, going against the spirit of the law, ACIP, and 47 other states.
🧵2/7
Louisiana law tells the pharmacy board to follow ACIP. ACIP says do not require a prescription, and 47 other states agree.
The Louisiana pharmacy board continues to require a prescription.
On the back end of this unprecedented 11th wave, "times they are a-changin." In particular, COVlD levels are shifting north and east.
Notice that few states are in the highest and lowest categories. Much of the south and west have considerable transmission post-peak. Many places in the north and east are seeing steady or increasing transmission after relatively lower levels.
Overall, levels are lower than the past few weeks, but transmission remains considerable. Those relying on anecdata (friends, coworkers, and family infected) may increasingly realize we are in a wave.
We estimate nearly 750,000 new daily infections nationwide, meaning approximately 1 in 66 people or 1.5% are actively infectious.
These estimates are derived by linking wastewater levels to IHME true case estimates using methodology commonly employed worldwide, detailed on the website, noted in a pre-print. Many publications in leading medical journals link wastewater data to key metrics that matter, noted in the online technical appendix.
In this week's report, we note adding North Dakota and Puerto Rico to the heat map in support of health equity. We have been imputing ND levels since the launch of PMC 3.0 using data from neighboring states. PR continues to report qualitative levels using the CDC format but is not longer included on the CDC website.
1/8 🧵
PMC COVlD Update, Sep 29, 2025 (U.S.)
State-level prevalence estimates, AL to MS. The levels use CDC labels, which tend to have an optimistic portrayal of risk. For example, CO is listed at "low" (by our estimate 1.5% infectious).
#MaskUp at 1.5% if having lapsed.
2/8 🧵
PMC COVlD Update, Sep 29, 2025 (U.S.)
State-level prevalence estimates, Missouri to Wyoming.
New York had *huge* retroactive upward corrections, and is now "High," as many residents hypothesized.
Note, Puerto Rico only provides CDC qualitative levels, so no data.