Expect 2 more weeks of very high and stable transmission before the summer wave accelerates.
Currently at an estimated 850,000 daily infections, 1 in 56 Americans contagious, 43,000 resulting Long COVID cases/day.
Deep Dive:
Over the next two weeks, we should see very high and stable transmission, before transmission increases rapidly. Note that transmission estimates are down marginally – of no practical impact – relative to last week. One might be tempted to consider that the summer wave is subsiding. That might be a 5-10% probability.
This is where the model gets interesting. The forecasts are derived from a combination of recent patterns in transmission (levels, change, rate of change, rate of rate of change) as well as historical medians for that date. If only using the recent patterns, a decline in the wave would be reasonable.
However, the historic data capture all of that useful information on variation in human behavior (back to school, end of summer vacations, flights, Labor Day) that focusing only on recent patterns would miss. Because behavioral patterns also fuel viral evolution, these historical data also get, to some extent, at the idea of viral evolution of new variants, which we do not track directly in the model.
When considering the forecast, view it two ways. One, based on current trends and historic data, this is what we would expect. Two, if human behavior defied historic trends, we could see something much different, such as a wave subsiding if everyone were more cautious than average this year, or unfortunately something slightly worse than predicted due to the decline in public health guidance on mitigation.
According to the composite forecasting model, that means hovering between 700,000 to 1,050,000 infections/day over the next month. Transmission is very high, and we may reach a later-summer peak of 1.1-1.3 daily infections around September 11.
Although the forecast is for steady transmission over the next two weeks, the forecast is volatile due to quality issues with incoming data.
Schools, medical facilities, and businesses should now escalate precautions and prepare for the disruption of a high percentage of the population getting sick through the remainder of 2024.
You can find the full PMC COVID-19 dashboard and weekly report for Aug 2, 2024 online.
In the report, I have included a link to the PPT slides from yesterday's Space on the new JAMA-NO #KeepMasksInHealthcare article.
Levels are flat during a relative "lull" in transmission.
▪️1 in 187 estimated actively infectious
▪️260,000 estimated new daily infections
▪️High: OK, MS, WV
▪️Moderate: VT
▪️All other states low/very low in relative transmission
🧵THREAD 1/6
COVID-19 persists in 2026.
We are in a relative "lull" following a 12th wave, but at a baseline of 200-300K estimated new daily infections.
Transmission was lower in the era many refer to as #DuringCOVID, when multi-layered mitigation was used instead of denial.
🧵THREAD 2/6
Transmission during a "lull" is high in an absolute sense. Many people are getting infected.
Simultaneously, its low in a relative sense, or compared to so-called "typical" transmission. In most places, it's a safer time for medical/dental care.
Transmission is stable in a relative "lull" nationally between waves.
We estimate that approximately 313,000 people are still getting infected per day, with outbreaks radiating from TN and MS.
🧵1 of 10 (don't miss #10)!
With limited data reported, Mississippi has an estimated 1 in 27 residents actively infectious.
In a room of 25 people, that's a 61% chance of exposure, if no testing/isolation protocols.
🧵2 of 10
1 in 24 people in Tennessee are estimated to be actively infectious with SARS-CoV-2. That's a 65% chance of exposure in a room of 25 people where nobody is testing/isolating.
This is an unethically misleading study with findings easily explained by residual confounding. Some health systems and patients have thorough record keeping. Others don't. All sorts of variables will correlate (infections, cancers, anything else tracked in medical records).
This is a really obvious issue for an international epi study. It should not have been published.
The above study is using the same processes the anti-vaxxers use -- junk epi that does not account for confounding -- to support whatever pre-conceived notions the authors have, with absurdly large effects.
Denial is but one of several obvious defense mechanisms people use to try to block their awareness of the ongoing toll of COVID-19. There are many others.
Short-term capital also plays a role, but even that requires a large dose of defense mechanisms.
During this 12th COVlD wave, the CDC reports 1-in-3 states have "High" or "Very High" levels.
PMC estimates the proportion of residents actively infectious (prevalence):
◾️USA: 1 in 67
◾️IA: 1 in 27
◾️MI: 1 in 25
◾️IN & CT: 1 in 23
◾️ME: 1 in 21
◾️OK & SD: 1 in 17
🧵1/
On average, Americans have have 5.0 cumulative SARS-CoV-2 infections.
This week's infections are expected to result in 1/4 to 1 million new #LongCOVID conditions and ≈2,000 excess deaths.
🧵2/
The wave peak is now estimated >10% higher than last week at 1.2 million new daily infections, nearly double the Delta wave.
We expect sustained high transmission (≈600,000 to 750,000 new daily infections) the next few weeks as COVlD circulates through schools/families.
🧵3/