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Emmanuel Profile picture
@ejustin46
Aug 16 • 5 tweets • 2 min read • Read on X
Those who WORE MASKS had HIGHER COMPASSION for others and LOWER SADISM compared to those who didn't wear masks ...

Amazing Review about PERSONALITY FACTORS and PANDEMIC-RELATED BEHAVIORS
frontiersin.org/journals/psych…
Image
2) The review examined how personality traits relate to pandemic-related behaviors like mask-wearing, social distancing, and hoarding. Key findings:

- Those who always wore masks had higher compassion for others and lower sadism compared to those who didn't always wear masks. Image
3) - Those who always socially distanced had higher openness, conscientiousness, and compassion for others compared to those who didn't.
- Those who hoarded had lower agreeableness compared to non-hoarders. Image
4) - The results suggest prosocial traits like compassion are linked to greater adherence to protective behaviors, while darker traits like sadism and low agreeableness relate to less compliance.
5) The authors propose that emphasizing altruistic messaging around vaccination and protective measures (e.g. how it protects vulnerable groups) could help boost prosocial traits and increase compliance.

Thanks for reading 🙏

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More from @ejustin46

Emmanuel Profile picture
Aug 18
TAILORED VACCINATION STRATEGIES to preserve the epitope repertoire and provide broad protection against evolving SARS-CoV-2 variants

A very interesting approach 💯
cell.com/heliyon/fullte…
Image
2) This study explored new vaccine strategies to address the rapidly evolving SARS-CoV-2 virus, especially the Omicron variants.

The key findings are:

- Vaccines made with stabilized spike proteins induced stronger antibody responses than regular spike proteins. Image
3) - Boosting with Omicron variants after initial D614G vaccination provided broader protection than boosting with D614G alone. The BA.4/5 booster was most effective.
- For those previously vaccinated with Omicron, a booster with pre-Omicron vaccines improved protection against.. Image
Read 5 tweets
Emmanuel Profile picture
Aug 18
RECOMBINATION EVENTS Among SARS-CoV-2 OMICRON SUBVARIANTS:
Impact on Spike Interaction With ACE2 Receptor and Neutralizing Antibodies

journals.sagepub.com/doi/10.1177/11…
Image
2) The study investigated the prevalence and impact of recombination events among SARS-CoV-2 Omicron BQ subvariants and "ML" (Multiple Lineages) sequences.

Key findings:

- Recombination was detected in over 50% of BQ and 82% of ML sequences, occurring mainly in the spike ...
Image
Image
3) ...and ORF1a genes. The USA, UK, and Australia were identified as global recombination hotspots.
- Docking analysis showed that BQ recombinant strains had increased binding affinity to the ACE2 receptor, mediated by a network of mutations (S373P, S375F, T376A) ... Image
Read 6 tweets
Emmanuel Profile picture
Aug 17
MPOX: An EXCELLENT OVERVIEW of Pathogenesis, Diagnosis, and Public Health Implications

Thanks to Franscesco @fbranda94
and his colleagues
mdpi.com/2077-0383/13/8…
Image
2) Mpox is an emerging zoonotic disease caused by the monkeypox virus, a member of the Orthopoxvirus genus. The epidemiology of mpox has evolved, with recent outbreaks marking a significant shift from previous patterns.
3) The 2022 outbreak spread rapidly across Europe, highlighting the virus's ability to disseminate globally.

Clinically, mpox presentations have changed, with more localized rashes and prodromal symptoms like intense headache and lymphadenopathy becoming more common.
Read 4 tweets
Emmanuel Profile picture
Aug 17
Mpox (MONKEYPOX)
What if we recalled the events of the last 12 months to gain insight into our current situation?
(mega-thread🧵)

28th DECEMBER 2023
2) 15th APRIL 2024
3) 15th APRIL 2024
Read 8 tweets
Emmanuel Profile picture
Aug 17
IMMUNITY KINETICS :

CYTOKINE STORM and ADAPTIVE IMMUNITY in 2 GRAPHS only
cell.com/heliyon/fullte…
Image
2) CYTOKINE STORM is a hallmark of severe COVID-19 cases, characterized by excessive production of inflammatory mediators like IL-6, IFN, and HMGB1. Alveolar macrophages play a central role, shifting towards a pro-inflammatory M1 phenotype that exacerbates lung damage. Image
3) ADAPTIVE IMMUNITY. SARS-CoV-2-specific T cells (both CD4+ and CD8+) as well as antibody-producing B cells are critical for controlling the infection, CD4+ T cells facilitate B cell responses and activate cytotoxic CD8+ T cells. Image
Read 4 tweets
Emmanuel Profile picture
Aug 17
BEWARE of SARS-COV-2 ANTI-IDIOTYPE ANTIBODIES 🤔

frontiersin.org/journals/immun…
Image
2) Anti-idiotype antibodies are a type of antibody that binds to the variable region (the "idiotype") of another antibody, rather than to the original antigen. This can trigger autoimmune reactions, potentially contributing to neurological issues. Image
3) This review describes patients who developed similar neurological problems after either COVID-19 infection or vaccination. The key finding is that these patients all had antibodies against the ACE2 protein, which the virus uses to infect cells. Image
Read 5 tweets

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