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Emmanuel Profile picture
@ejustin46
Aug 19 • 5 tweets • 2 min read • Read on X
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HEALTH and ECONOMIC BURDEN of long COVID in AUSTRALIA over 2022-2024

A very interesting study of @Globalbiosec and colleagues
onlinelibrary.wiley.com/doi/10.5694/mj…
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2) The study estimates the substantial health and economic burden of long COVID in Australia over 2022-2024. Modeling projects that even a small proportion of infected people developing long COVID could have major population health and economic impacts. Image
3) The key findings include:

- An estimated 172,530-872,799 Australians (0.7-3.4%) will have long COVID symptoms by end of 2024, including 7,902-30,002 children aged 0-4.

- The labor loss attributable to long COVID in 2022 ... Image
4) ... is projected at 102.4 million hours (0.48% of total worked hours), with the greatest impact on those aged 30-49.
- The estimated mean GDP loss in 2022 is $9.6 billion (0.5% of GDP), due to reduced labor supply and use of other production factors. Image
5) The authors argue this burden is comparable to leading causes of disease in Australia, but uniquely affects working-age adults. They call for a paradigm shift from just managing acute COVID-19 to also preventing and treating long COVID.

Thanks for reading 🙏 Image

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More from @ejustin46

Emmanuel Profile picture
Aug 20
H5N1.
From ENDEMIC to PANDEMIC ?

H/t @FluAlert_
biorxiv.org/content/10.110…
Image
2) This study shows the H5N1 influenza virus is evolving to evade existing antibodies over time. Computational modeling found the virus' ability to bind to antibodies has weakened across many different animal hosts and locations. Image
3) Certain mutations make the virus less susceptible to antibody neutralization. The lack of a single virus reservoir highlights the challenge in controlling its spread. Image
Read 4 tweets
Emmanuel Profile picture
Aug 20
From human herpes virus-6 reactivation, to autoimmune reactivity against tight junctions and neuronal antigens, to inflammation, depression, and chronic fatigue syndrome due to Long COVID 😨

onlinelibrary.wiley.com/doi/10.1002/jm…
Image
2) This study found that Long COVID and its symptoms like chronic fatigue, depression, and anxiety are linked to an overactive immune system attacking the gut's tight junctions and brain proteins. Image
3) The immune reactions seem to be triggered by reactivation of the HHV-6 virus, leading to a "leaky gut" that allows bacteria to enter the bloodstream and trigger further autoimmune responses. Image
Read 4 tweets
Emmanuel Profile picture
Aug 19
WHY SARS-CoV-2 is UNIQUE ?

Immune response to SARS-CoV-2 infection, compared with other viral infections (200 studies, 35 different viruses in 18 viral families) 💯👍
academic.oup.com/pnasnexus/arti…
Image
2) This study compared the immune response to SARS-CoV-2 (the virus that causes COVID-19) with other viral infections. The results show that infections with the Coronaviridae virus family, including SARS-CoV-2, trigger a unique pattern of immune molecules ...
Image
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3) ...called cytokines and chemokines. Key differences were found in levels of IL-1RA, CXCL9, CCL4, IFN-λ1, IP-10, and IL-27, with the type III interferon IFN-λ1 being a major distinguishing factor. Image
Read 5 tweets
Emmanuel Profile picture
Aug 19
BRAIN EFFECTS of MILD COVID-19 in HEALTHY YOUNG ADULTS 😨😨😨

A pilot study
cell.com/heliyon/fullte…
Image
2) This study looked at the effects of mild COVID-19 on the brains of healthy young adults. The researchers compared brain scans and cognitive tests done before the pandemic to those done after some participants had mild COVID-19. Image
3) They found that the COVID-19 group showed decreases in measures of brain structure in certain frontal regions, suggesting possible injury or inflammation. The COVID-19 group also showed trends towards declines in processing speed, memory, and other cognitive functions ...
Read 6 tweets
Emmanuel Profile picture
Aug 19
How COVID-19 is WORSENING the NEUROIMMUNE SYSTEM in ALZHEIMER'S PATIENTS ?

jneuroinflammation.biomedcentral.com/articles/10.11…
Image
2) The study explores how COVID-19 affects the brains of Alzheimer's disease (AD) patients. Researchers analyzed brain tissue from AD patients who survived COVID-19 and compared it with AD patients who did not have the virus. Image
3) They found that those who had COVID-19 showed increased levels of amyloid-beta (Aβ) in certain brain areas, but similar tau levels. Additionally, there was a significant loss of immune cells called microglia, and reduced numbers of astrocytes in COVID-AD patients. Image
Read 4 tweets
Emmanuel Profile picture
Aug 18
Why PEOPLE ALIENATED from SOCIETY, BELIEVE in CONSPIRACY THEORIES ?

An amazing study 💯👍
cell.com/heliyon/fullte…
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2) This study found that people who feel alienated from society are more likely to believe in conspiracy theories, as these beliefs can provide a sense of meaning and belonging that they lack in their lives. When people feel discriminated against or disconnected ... Image
3) ...from mainstream institutions, conspiracy theories offer an alternative way to find purpose, coherence, and significance. However, for those who don't feel alienated, conspiracy beliefs are not linked to increased meaningfulness. Image
Read 4 tweets

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