These findings are from a study in @PhysRevE which employs cavity quantum electrodynamics to explore entangled biphoton generation through cascade emission as a potential source for the synchronized activity of neurons. 2/13 journals.aps.org/pre/abstract/1…
Quantum entanglement is the phenomenon of a group of particles being generated, interacting, or sharing spatial proximity in such a way that the quantum state of each particle of the group cannot be described independently of the state of the others. 3/13
The idea that the human brain contains quantum properties was first suggested in the 90s by physicist @penrose and anesthesiologist @StuartHameroff with their “orchestrated objective reduction” model of a consciousness. 4/13
The synchronization of neurons within the cerebral cortex serves as the foundation for diverse neurobiological processes, closely linked to anomalies in brain function and brain diseases. 5/13
Recent studies have highlighted the role of the photon as a quantum object whereby ultraweak photon emission in living organisms is now implicated in neuronal function. 6/13
Photons released during tricarboxylic acid cycle in neurons resonantly couple to C-H bond vibrons in lipid molecules, altering possibly the dielectric constant of the membrane to enhance action potential conduction. 7/13
The myelin sheath, a lipid membrane encasing the outer side of a neuron's axon, provides energy to the axon, enhances action potential conduction, and acts as an insulator in the nervous system. 8/13
The myelin sheath is generally regarded only as an insulator; however, emerging evidence suggests myelin's plasticity, indicating its role beyond insulation and its potential to promote neural phase synchronization. 9/13
This study demonstrates that the vibrational spectrum of C-H bonds in lipid molecule's tails, within the myelin sheath encasement, can generate quantum entangled photon pairs through cascade radiation from the second excited state to the ground state. 10/13
This indicates that the cylindrical cavity formed by a myelin sheath can facilitate spontaneous photon emission from the vibrational modes and generate a significant number of entangled photon pairs. 11/13
The abundance of C-H bond vibration units in neurons can therefore serve as a source of quantum entanglement resources for the nervous system. 12/13
Overall, these findings may offer insight into the brain's ability to leverage these resources for quantum information transfer, thereby elucidating a potential source for the synchronized activity of neurons. 13/13
@skdh thoughts?
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The mitochondria may be central to mental disorders.
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These findings are from a review in @ELSneuroscience which summarizes the existing literature on mitochondrial dynamics perturbations in psychiatric disorders/neuropsychiatric phenotypes. 2/13 sciencedirect.com/science/articl…
Mitochondria, the double membrane organelles that produce ATP and carry their own circular double-stranded mtDNA, orchestrate cell metabolism, redox status and calcium buffering, and are emerging pathobiological hubs in neuropsychiatry. 3/13
These findings are from a study in @NatureComms which analyzed cross-sectional brain images from 4,222 individuals with schizophrenia and 7,038 healthy subjects to identify two distinct neurostructural subgroups in schizophrenia. 2/11 nature.com/articles/s4146…
Although there are approximately 26 million people with schizophrenia, the etiology is still not fully understood, and people with schizophrenia show a substantial heterogeneity in clinical symptoms, disease progression, treatment response, and other biological markers. 3/11
These findings are from a review in @npp_journal which provided an overview of a large body of evidence for the structural and metabolic brain alterations in schizophrenia. 2/10 nature.com/articles/s4138…
Schizophrenia is generally a chronic and disabling condition associated with positive (psychotic symptoms such as delusions, hallucinations), negative (such as anhedonia, asociality) and cognitive symptoms (such as impaired working memory and executive function). 3/10
This is the free-energy formulation of the human psyche.
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These findings are from a study in Physics of Life Reviews which unifies dominant schools of thought spanning neuroscience and psychology by presenting a new theory of the human brain called the hierarchically mechanistic mind (HMM). 2/11 sciencedirect.com/science/articl…
The HMM defines the embodied, situated brain as a complex adaptive system that actively minimises the entropy of human sensory and physical states by generating action-perception cycles that emerge from dynamic interactions between hierarchically organised neurocognitive mechanisms. 3/11
These findings are from a perspective in @CommsPsychol which proposes that subjective and brain-based alterations caused by psychedelics increases the quantity and subjective intensity of insights and thence beliefs, including false ones. 2/11 nature.com/articles/s4427…
When an idea or problem solution appears, it can produce a distinct and powerful phenomenology—a feeling of profound understanding and truth known as an insight moment. 3/11