The heart and brain are interconnected.

🧵1/11 These findings are from a study in @ScienceMagazine which used multiorgan MRI and genetic data from >40,000 subjects to quantify interorgan connections between the heart and brain. 2/11 science.org/doi/10.1126/sc…

Life satisfaction is highly consistent with your personality.

🧵1/10 These findings are from a study in @APA_Journals which used data from three samples in different languages to examine the extent to which life satisfaction reflects personality traits. 2/10 psycnet.apa.org/record/2024-93…

This is your brain on psilocybin.

🧵1/10 These findings are from a study in @medrxivpreprint which tracked brain changes in healthy adults before, during, and for up to 3 weeks after oral psilocybin and methylphenidate and again 6+ months later. 2/10 medrxiv.org/content/10.110…

Coffee changes connectivity in the brain.

🧵1/11 These findings are from a study in @FrontiersIn which used functional connectivity approaches to study resting-state fMRI data in a group of habitual coffee drinkers. 2/11 frontiersin.org/articles/10.33…

Pharmacogenomic-guided treatment for depression may save the health care system $956 million.

🧵1/9 These findings are from a study in @CMAJ which developed a microsimulation model of care pathways for depression to evaluate the effectiveness and cost-effectiveness of pharmacogenomic testing from the public payer’s perspective over 20 years. 2/9 cmaj.ca/content/195/44…

There are six biotypes of depression.

🧵1/10 These findings are from a study in @NatureMedicine which derived personalized and interpretable scores of brain circuit dysfunction grounded in a theoretical taxonomy to subdivide participants into distinct biotypes. 2/10 nature.com/articles/s4159…

Greater stomach-brain coupling is associated with worse mental health.

🧵1/10 These findings are from a study in @biorxivpreprint which investigated the relationship between the stomach-brain axis and mental health symptoms in 243 participants using a machine learning approach. 2/10 biorxiv.org/content/10.110…

Immune dysregulation is central to depression and bipolar disorder.

🧵1/11 These findings are from a study in @transl_psych which reviewed the current literature on dysregulation of the immune response system in depression and bipolar disorder. 2/11 nature.com/articles/s4139…

There is a U-shaped association between BMI and mental health.

🧵1/10 These findings are from a study of 1,036,869 adolescents in @JAMAPsych which aimed to determine how the association between body mass index (BMI) and mental health change over time among adolescents. 2/10 jamanetwork.com/journals/jamap…

The neuroplasticity framework of depression has the potential to replace the serotonin deficit hypothesis.

🧵1/17 The serotonin deficit hypothesis explanation for depression has persisted among clinicians and the general public alike despite insufficient supporting evidence. 2/17 nature.com/articles/s4138…

Poor body health is a more pronounced manifestation of mental illness than poor brain health.

🧵1/12 These findings are from a study including 85,748 adults with neuropsychiatric disorders and 87,420 healthy control individuals in @JAMAPsych which aimed to evaluate the health status of the brain and 7 body systems across neuropsychiatric disorders. 2/12 jamanetwork.com/journals/jamap…

Instagram photos reveal predictive markers of depression.

🧵1/12 These findings are from a study in @epj_ds which aimed to successfully identify and predict markers of depression in Instagram users’ posted photographs. 2/12 epjdatascience.springeropen.com/articles/10.11…

This is the temporo-spatial theory of consciousness.

🧵1/13 This theory is from a study in Neuroscience & Biobehavioral Reviews which posits that four neuronal mechanisms account for different dimensions of consciousness. 2/13 sciencedirect.com/science/articl…

Depression may be contagious through a dysfunctional mirror neuron system.

🧵1/11 This discussion is from a review article in Neuroscience & Biobehavioral Reviews which describes the theory of ‘contagious depression’, whereby depression can be induced or triggered by our social environment. 2/11 sciencedirect.com/science/articl…

This is a map of happiness within a social network.

🧵1/9 These findings are from a study of 4739 people in @bmj_latest which aimed to evaluate whether happiness can spread from person to person and whether niches of happiness form within social networks. 2/9 bmj.com/content/337/bm…

Mental disorders might be transmitted within adolescent peer networks.

🧵1/11 These findings are from a study of 713,809 adolescents in @JAMAPsych which aimed to examine whether having classmates with a mental disorder diagnosis in the ninth grade is associated with later risk of being diagnosed with a mental disorder. 2/11 jamanetwork.com/journals/jamap…

Most published research findings are false.

🧵1/13 This view is from an essay in @plosmedicine which discusses the increasing concern of the reliability of research findings. 2/13 journals.plos.org/plosmedicine/a…

This is a map of the duration of untreated psychosis worldwide.

🧵1/8 These findings are from a large-scale meta-analysis of 369 studies in Psychological Medicine which aimed to estimate the average duration of untreated psychosis around the world. 2/8 cambridge.org/core/journals/…

Over 2h of daily sunlight exposure was associated with reduced total brain volumes.

🧵1/8 These findings are from a study of 27,474 people in @SciReports which aimed to determine whether there are associations between sunlight exposure and brain structural markers. 2/8 nature.com/articles/s4159…

Gut microbiota act as the ‘metabolic machinery’ of mental disorders.

🧵1/10 These findings are from a systematic review in @molpsychiatry which aimed to understand the emerging role of gut microbiota in the field of psychiatry. 2/10 nature.com/articles/s4138…

Skipping breakfast is associated with an increased odds of depression.

🧵1/8 These findings are from a meta-analysis of 14 studies (399,550 individuals) in Nutritional Neuroscience which aimed to summarize the evidence on the association between skipping breakfast and mental health. 2/8 tandfonline.com/doi/abs/10.108…