This virus is associated with food addiction via indirect modulation of serotonin and dopamine.
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These findings are from a study in @NatMetabolism which investigated food addiction traits across multiple human cohorts and their relationship with the gut microbiome using shotgun metagenomics. 2/10 nature.com/articles/s4225…
Feb 27 • 11 tweets • 3 min read
Five days of ultra-processed foods changed the insulin and reward functions of the brain.
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These findings are from a study in @NatMetabolism which investigated the short-term effects of an ultra-processed, high-caloric diet on brain insulin action before significant weight gain. 2/10 nature.com/articles/s4225…
Feb 26 • 9 tweets • 2 min read
People with ADHD have delayed cortical maturation.
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These findings are from a study in @PNASNews which estimated cortical thickness at >40,000 cerebral points from 824 magnetic resonance scans acquired prospectively on 223 children with ADHD and 223 typically developing controls. 2/9 pnas.org/doi/10.1073/pn…
Feb 25 • 9 tweets • 2 min read
In our new study, we found that meeting more 24h movement guidelines was associated with less depressive symptoms.
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These findings are from our study in @SpringerNature which aimed to examine the association between meeting the 24-h movement guidelines and depressive symptoms among U.S. adolescents. 2/9 link.springer.com/article/10.100…
Feb 24 • 11 tweets • 3 min read
Exercise is medicine for your mitochondria.
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These findings are from a review in @AnnualReviews which builds on a biological framework that distinguishes between domains of mitochondrial biology to evaluate how different exercise prescriptions influence mitochondrial adaptations to training. 2/11 annualreviews.org/content/journa…
Feb 23 • 10 tweets • 2 min read
7 hours of sleep is associated with the lowest phenotypic age.
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These findings are from a study in @SciReports which aimed to (i) identify the sleep duration trend in US adults; (ii) investigate the relationship between sleep duration and phenotypic age; and (iii) explore the role of exercise in this relationship. 2/9 nature.com/articles/s4159…
Feb 22 • 9 tweets • 3 min read
Low creatine in the prefrontal cortex is associated with depression.
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These findings are from a study in @SageJournals which used 1H-Magnetic Resonance Spectroscopy and magnetic resonance imaging (MRI) to understand the neural mechanisms of depressive symptoms. 2/9 journals.sagepub.com/doi/10.1177/02…
Feb 21 • 10 tweets • 3 min read
In this study, suppression of unwanted thoughts improved mental health - this goes against the century-old wisdom, “don’t bottle up your emotions”.
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These findings are from a study in @ScienceAdvances which had 120 adults from 16 countries undergo 3 days of online training to suppress either fearful or neutral thoughts. 2/9 science.org/doi/10.1126/sc…
Feb 20 • 8 tweets • 2 min read
A single walk could add over 6 hours of life expectancy.
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These findings are from a study in @BJSM_BMJ which estimated how much low physical activity (PA) reduces life expectancy, and how much life expectancy could be improved by increasing PA levels for both populations and individuals. 2/8 bjsm.bmj.com/content/early/…
Feb 19 • 9 tweets • 3 min read
COVID-19 can cause brain cells to fuse.
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These findings are from a study in @ScienceAdvances which explored how viruses alter the function of the nervous system. 2/9 science.org/doi/10.1126/sc…
Feb 18 • 10 tweets • 3 min read
The metabolic overdrive hypothesis proposes that bipolar mania represents a condition of heightened cerebral energy metabolism facilitated by hyperglycolysis and glutaminolysis.
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These findings are from a paper in @molpsychiatry which describes the experience of mania from a metabolic perspective. 2/9 nature.com/articles/s4138…
Feb 17 • 12 tweets • 3 min read
Schizophrenia can be conceptualized as a disorder of broken brain bioenergetics.
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These findings are from a review in @molpsychiatry which discusses the relationship between dysfunction of various metabolic pathways across different brain regions in relation to schizophrenia. 2/11 nature.com/articles/s4138…
Feb 16 • 14 tweets • 3 min read
There is potential for creatine supplementation as a treatment for Alzheimer's dementia.
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These findings are from a review in @jnutritionorg which discusses the link between creatine (Cr) and Alzheimer's disease (AD) and the potential for Cr supplementation as a treatment for AD. 2/12 cdn.nutrition.org/article/S2475-…
Feb 16 • 10 tweets • 2 min read
After just one night of sleep deprivation, the brain begins to accumulate β-amyloid - a key protein in Alzhiemer’s dementia.
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These findings are from a study in @PNASNews which used PET and 18F-florbetaben to measure brain Aβ burden (ABB) in 20 healthy controls tested after a night of rested sleep (baseline) and after a night of sleep deprivation. 2/10 pnas.org/doi/10.1073/pn…
Feb 15 • 11 tweets • 3 min read
The energy landscape of neurophysiological activity.
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These findings are from a study in @SciReports which used a maximum entropy model of brain dynamics informed by white matter tractography to determine how anatomical structure impacts the complex functional dynamics of the brain. 2/11 nature.com/articles/s4159…
Feb 14 • 9 tweets • 2 min read
Being addicted to your phone is associated with reduced brain gray matter volume.
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These findings are from a study in @FrontPsychol which aimed to explore the microstructural variations associated with Mobile phone dependence (MPD) as measured with functional Magnetic Resonance Imaging (fMRI). 2/8 frontiersin.org/journals/psych…
Feb 13 • 9 tweets • 2 min read
The gut-brain axis has therapeutic implications for neurodegenerative disorders.
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These findings are from a paper in @Nutrients_MDPI which provided an overview of the major components of the gut–brain axis (GBA), as well as therapeutic approaches targeting the GBA to ameliorate neurodegenerative disorders (NDDs). 2/9 mdpi.com/2072-6643/15/2…
Feb 12 • 10 tweets • 3 min read
A single dose of psilocybin was efficacious in severe treatment-resistant depression.
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These findings are from a study in @APAPubJournals which documented the safety and efficacy of psilocybin in patients with severe treatment-resistant depression (TRD). 2/10 psychiatryonline.org/doi/10.1176/ap…
Feb 11 • 10 tweets • 2 min read
Dog ownership is associated with a reduced odds of dementia - cat ownership has no effect.
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These findings are from a study in @ElsevierConnect which examined associations of the interaction between dog/cat ownership, exercise habits and social isolation with dementia. 2/9 sciencedirect.com/science/articl…
Feb 10 • 9 tweets • 3 min read
A high single dose of creatine can partially reverse metabolic alterations and cognitive deterioration associated with sleep deprivation.
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These findings are from a study in @SciReports which orally administered subjects a high single dose of creatine monohydrate (0.35 g/kg) while performing cognitive tests during sleep deprivation. 2/9 nature.com/articles/s4159…
Feb 9 • 9 tweets • 2 min read
Exercise increases the size of the hippocampus and improves memory.
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These findings are from a study in @PNASNews which randomly assigned older adults to receive either moderate-intensity aerobic exercise 3 d/wk or stretching and toning exercises that served as a control. 2/9 pnas.org/doi/10.1073/pn…