A Simplified Explanation of Fibrin's Role in COVID-19
The Problem:
* COVID-19 can cause blood clots and brain issues.
* These problems can continue even after the infection is gone.
* Scientists don't fully understand how these clots form or what they do to the body.
The Discovery:
* Scientists found that a protein called fibrin plays a big role in these problems.
* Fibrin helps form blood clots.
* In COVID-19, fibrin can bind to the virus and cause more inflammation.
How Fibrin Works:
* Clot Formation: Fibrin helps create blood clots, which can be harmful if they form in the wrong places.
* Inflammation: Fibrin can also trigger inflammation, which can damage tissues.
* Brain Problems: Fibrin can lead to problems in the brain, including inflammation and damage to brain cells.
Potential Solution:
* The scientists found that a special antibody might be able to stop fibrin from causing these problems.
* This antibody could be a possible treatment for COVID-19, especially for people with severe symptoms or long-lasting effects.
In Conclusion:
This research shows that fibrin is a key player in the problems caused by COVID-19. Understanding fibrin's role could lead to new treatments for this disease.
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For ongoing long COVID patients, the top three reasons to consider a PET scan are:
1.Detecting Hidden Inflammation and Organ Damage
PET scans, especially when combined with MRI (PET/MRI), can reveal persistent inflammation in the heart, lungs, and other organs—even when standard tests appear normal. This helps identify patients at risk for future cardiopulmonary complications such as heart failure, pulmonary hypertension, or valvular disease.
Identifying Brain and Nervous System Involvement
PET scans (such as brain FDG-PET) can uncover hypometabolism or inflammation in the brain, which may explain cognitive, neurological, or autonomic symptoms in long COVID patients. This is particularly valuable for distinguishing long COVID from other neurological or psychiatric disorders.
Tracking Viral Persistence and Immune Activation
Specialized PET imaging agents can help detect viral reservoirs and ongoing immune activation in deep tissues, such as the gut or brainstem. This approach may clarify the underlying cause of persistent symptoms and guide personalized treatment strategies.
These reasons highlight how PET imaging can provide objective evidence of ongoing disease processes, support early intervention, and help tailor management for long COVID patients.
It does sound ‘over the top’ & who wants to believe we are letting our kids get repeated Cov infections potentially destroying their organs.
The tragedy of it all- we knew in 2020. Ask teachers if they see a difference in behavior, mood, memory recall, a dramatic increase in ADHD, and most importantly, look at the test scores and how they have plummeted long after a 3 month lockdown 6 yrs ago.
COVID-19 has been linked to potential dementia risk in young people through mechanisms involving direct neurological damage, vascular changes, and systemic inflammation. Below are key studies and findings that explore this connection:
1. Systemic Vascular and Neurological Pathways**
A 2021 review highlighted COVID-19’s ability to trigger systemic vascular alterations and neuroinflammation, potentially accelerating neurodegenerative processes. Cognitive decline pathways include blood-brain barrier disruption and hypoxic brain injury, which may exacerbate pre-existing dementia or initiate early-onset cases[1].
2. Long COVID and Neurological Symptoms**
A Northwestern Medicine study (2024) found that 10 months post-infection, young adults (18–44) exhibited worsened neurologic symptoms, including cognitive dysfunction, insomnia, and memory deficits. These effects occurred regardless of initial infection severity[2].
My Dear Friends and Fellow Advocates,
With a heart full of passion and gratitude, I write to you today. For five long years, we have fought tirelessly for a cause that too often felt invisible to the world. We’ve faced indifference, we’ve battled through personal struggles—4 to 5 infections, no less—and yet, we refused to succumb to the illness that sought to break us. Yes, I am tired. Yes, I have felt frustrated, defeated even. But here we are. WE MADE IT.
1🧵
Through every obstacle, every moment of doubt, we stood firm—not just for ourselves but for humanity. For our love of people. For the belief that no one should ever endure what we have endured. And let me tell you this: after this past week, I am more inspired than ever. My conviction has been reignited, my spirit rekindled. I come back to our mission with new fervor and light, and I know—deep in my soul—that together we can achieve even more. 2🧵
This is not just my success or yours; this is our collective success. Each and every one of you has played an integral role in bringing Long Covid Awareness Month to life. You gave it your all—your time, your energy, your heart—and it shows. The world is beginning to hear us because of YOU. 3 🧵
Metformin and COVID-19: A Potential link
Metformin, primarily used for treating type 2 diabetes, has shown potential benefits in managing COVID-19. Here's a breakdown of the potential mechanisms:
Potential Benefits of Metformin for COVID-19
* Reduced viral load: Studies suggest metformin can lower the amount of virus in the body, potentially reducing the severity of infection.
* Lower risk of hospitalization: Research indicates metformin might decrease the chances of needing hospitalization for COVID-19.
* Reduced risk of long COVID: Evidence suggests metformin could lower the likelihood of developing long-term symptoms after COVID-19.
* Anti-inflammatory effects: Metformin has anti-inflammatory properties, which could help combat the excessive inflammation often seen in severe COVID-19 cases.
* Improved glucose control: For patients with diabetes, maintaining good blood sugar levels is crucial in fighting infections. Metformin can help with this.
How Does It Work?
While the exact mechanisms aren't fully understood, researchers believe metformin may:
* Interfere with the virus's ability to replicate
* Modulate the immune response to prevent excessive inflammation
* Improve overall health and metabolic function, making the body better equipped to fight infection
Important Considerations
* More research is needed: While promising, current evidence is still developing.
* Not a cure: Metformin is not a replacement for vaccines or other recommended COVID-19 treatments.
* Individual variation: Response to metformin can vary among individuals.
In light of @DrEricDing s advice on the upcoming pandemic, I wanted to share a few things which everyone needs to have available in the event of an emergency- tornados, power outages, fires, hurricanes, sheltering in place, and deadly viruses ripping through the country unchecked.
AI agrees:
Here's why it's important to be prepared for H5N1:
* While H5N1 currently has low transmission among humans, it has the potential to mutate & become more transmissible.
* If it were to mutate and spread easily between people, it could cause a pandemic with serious health consequences.
* Being prepared can help mitigate the impact of an outbreak, both for individuals and for healthcare systems.
Based on prior experience, I am confident we were not prepared for catastrophic events. FEMA has provided resources for you & your family. Please print out.
FOR PARENTS:
Documents to keep in a fireproof bag. (I just had a house fire 🔥 and wish I had done more to prepare.)