Becky Ancira Robertson Profile picture
Aug 29, 2024 1 tweets 1 min read Read on X
In a layman’s terms:

A Simplified Explanation of Fibrin's Role in COVID-19
The Problem:
* COVID-19 can cause blood clots and brain issues.
* These problems can continue even after the infection is gone.
* Scientists don't fully understand how these clots form or what they do to the body.
The Discovery:
* Scientists found that a protein called fibrin plays a big role in these problems.
* Fibrin helps form blood clots.
* In COVID-19, fibrin can bind to the virus and cause more inflammation.
How Fibrin Works:
* Clot Formation: Fibrin helps create blood clots, which can be harmful if they form in the wrong places.
* Inflammation: Fibrin can also trigger inflammation, which can damage tissues.
* Brain Problems: Fibrin can lead to problems in the brain, including inflammation and damage to brain cells.
Potential Solution:
* The scientists found that a special antibody might be able to stop fibrin from causing these problems.
* This antibody could be a possible treatment for COVID-19, especially for people with severe symptoms or long-lasting effects.
In Conclusion:
This research shows that fibrin is a key player in the problems caused by COVID-19. Understanding fibrin's role could lead to new treatments for this disease.

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More from @AnciraBecky

May 26
Several categories of serious medical errors aka “never events” have increased since 2020, based on the most authoritative data available from The Joint Commission & other national reporting systems. The rise is not uniform across all error types, but the trend is clear: wrong‑site surgeries, retained surgical items, & other sentinel events have climbed noticeably since the pandemic era began.

1/
What the data shows (2020 → 2023)

1. Wrong‑site /wrong‑patient / wrong‑procedure surgeries:
The Joint Commission reported 112 wrong‑surgery sentinel events in 2023, & this category increased by 26% from 2022 to 2023.

These errors include operating on the wrong limb, wrong organ, wrong vertebral level, or even the wrong patient.

2/
📈 What the data shows from 2020 → 2023:
1. Wrong‑site / wrong‑patient / wrong‑procedure surgeries:
• The Joint Commission reported 112 wrong‑surgery sentinel events in 2023, & this category increased by 26% from 2022 to 2023.  
• These errors include operating on the wrong limb, wrong organ, wrong vertebral level, or even the wrong patient.

3/
Read 13 tweets
Apr 18
The recent wave of clinical findings confirm what many of us have felt in the trenches of advocacy: COVID-19 is not just a respiratory event; it is a profound neuropsychiatric and multi-systemic disruptor. Research indicates that survivors face a significantly higher risk of mental health challenges, ranging from substance use disorders to severe anxiety. While it is undeniably true that the trauma of a pandemic can exacerbate preexisting conditions, we must be vigilant against the "fine line" of psychologizing what is fundamentally a biological assault on the body.
1/7.
@winslow_la @elisaperego78 @markwarling3 @LauraMiers
The Danger of the Single Specialist
When we view the neurocognitive decline, depression, or anxiety following an infection through a purely psychological lens, we risk missing the physical engines driving those symptoms: viral persistence, chronic immune activation, & endothelial damage.

Neuropsychiatric complexity: Symptoms like "brain fog" or memory loss are often linked to measurable brain hypo-metabolism & structural changes in functional connectivity.
2/7
The "Whole-Body" Mandate: Long COVID is associated with over 200 symptoms affecting the heart, lungs, gut, & nervous system. To treat the "anxiety" without checking for autonomic dysfunction (like POTS) or microbiota dysbiosis is to treat a shadow while the fire still burns.
3/7
Read 7 tweets
Apr 8
A COVID infection can lower or dysregulate estrogen by directly stressing or damaging the ovary & uterine lining, disrupting brain–ovary signaling, & driving chronic inflammation that pushes the body toward a low‑estrogen, perimenopause‑like state.

Key mechanisms:
- Ovarian stress or injury
- Ovaries express ACE2 & other SARS‑CoV‑2 entry factors, so infection & the associated immune response can impair follicles that produce estradiol.
- Case reports describe young women developing amenorrhea & premature ovarian insufficiency after COVID, with low estrogen & high FSH, suggesting impaired ovarian reserve after infection.
1/9
@elisaperego78 @NotOstriching Def not discussed enough. My estrogen went to 0 during acute infection.
Hypothalamus–pituitary disruption:

•Estrogen production depends on brain signaling (GnRH → LH/FSH → ovary); severe infection, high fevers, and systemic inflammation can blunt this axis, temporarily reducing estrogen output & causing missed or irregular periods.
- This same axis disruption is seen in other critical illnesses, & COVID appears to follow that pattern in some people, especially with long‑lasting symptoms.
2/9
@VirusesImmunity
Inflammation & immune–hormone crosstalk:

- Estrogen normally restrains excessive inflammation & modulates Th1/Th2 cytokines; low estrogen favors more pro‑inflammatory cytokines such as IL‑6 & TNF‑α.
- A strong or persistent inflammatory response to SARS‑CoV‑2 can therefore both result from low estrogen & further suppress normal ovarian function, creating a vicious cycle of inflammation & estrogen depletion.
4/9
@DavidJoffe64
Read 8 tweets
Mar 15
💜 Just sharing a part of my heart… to clarify for my peers & those making inquiries in DMs.

1/
Let me be clear: Advocacy has become the spine of my life, not a side project, & it honestly hurts that people I love are reading my choices as betrayal when every single decision I make is about protecting & honoring our community, my family in this.

#LongCovidAwareness
2/
This event today on March 15th is not about the rest of the world, & it is not about going viral. It’s for people with Long Covid. I asked my groups, my Facebook communities, & my 42‑person therapy group what they actually wanted, & not one person said, “I want to hear a tiny corner of MedTwitter talk about their own experiences for 24 hours.” Maybe it would be different if I didn’t host Spaces 4 days a week where we are all too familiar with each other’s experiences. What they did want was to hear from people on the front lines—what they’re seeing, what’s worked & failed, how they’ve found inner strength, & whether we are being seen & remembered. They wanted tools, validation, & maybe a sprinkle of hope, something they could bring to their doctor or therapist or family to say, “Look, this is real.” That is what I built this around.

#LongCovidAwarenessDay
3/
I have been very deliberate about centering patients, even if it doesn’t look like the usual “tell your story into the void” format. Many people with Long Covid want anonymity. Many are too sick to be public, or simply cannot afford to relive their trauma onstage. And I respect that. More than half of the people speaking have Long Covid themselves and are advocating on behalf of all of us in whatever capacity they’re able. I’ve known many of them for 5–6 years, back when we all still seemed to be on the same side, & I know I can rely on them. They aren’t props; they are my peers.  

#LongCovidAwarenessDay
Read 12 tweets
Mar 7
On this International Long Covid Awareness Day, 2026, we are doing something rare, something radical, & something deeply needed: we are bringing the people who know the most, & the people who are struggling the most, into the same room for 24 hours straight of truth, science, advocacy, & solidarity.
1/

@morgfair @19joho @TheReSisters2 @EmJayNabuurs @MattMcGorry @Alyssa_Milano @selma_hayek @LolaGerms @CarnivoraCC @HolleyM20 @VirusesImmunity @dryostradamus
x.com/i/spaces/1jgxg…
For one full day, this Space becomes a living bridge between cutting‑edge research and the daily reality of Long Covid. Some of the most respected doctors and scientists in the world are joining us to share the latest innovations, discoveries, and emerging treatments shaping the future of Long Covid care. They are the ones pushing the science forward when the world would rather look away—standing with us, not above us. 2/

@yaneerbaryam @MsJulieSLam @elisaperego78 @michael_hoerger @AndrewEwing11 @DavidJoffe64 @DrMarjorieRobe1 @DaniBeckman @Eerrnn @winslow_la @longcovidriseup @hoolie_r @HollyMars2 @D_Bone @drseanmullen @SalamonSMDImage
Alongside them, you’ll hear from patients whose lives have been forever altered by this virus—parents, workers, caregivers, disabled & chronically ill people who never chose this path, but walk it every day with courage, grief, humor, & fight. Their stories are the heartbeat of this marathon. Tonight, evidence & experience sit side by side, & neither has to apologize for taking up space.
3/
@LongCFoundation @LongCLand @ModelAyshaMirza @DebHolloway @debbieACSW @keetmuise @broadwaybabyto @DailyJLee @LauraMiers @MeetJess @HarrySpoelstra @scott_squiresImage
Read 7 tweets
Mar 4
“She’s still in there.” Please don’t give up on her- a mother’s plea. 🙏

First, I want to acknowledge how confusing and painful it can be to see someone you love change after COVID and brain injury. These changes are not her fault, and they are not a choice; they are the result of real physical damage to the parts of her brain that used to make certain things feel easy or automatic, like empathy, memory, and emotional balance.

What COVID did to her brain:
COVID is not just a “lung virus.” It can inflame and injure the brain, including the frontal lobes—the areas behind the forehead that help with personality, empathy, decision‑making, impulse control, planning, and flexible thinking. 1/11
When those areas are damaged or have very low electrical activity, people can develop:
• Blunted or unpredictable emotions (quick temper, big mood swings, “all‑or‑nothing” reactions).
• Trouble with empathy and reading other people’s feelings, even if they want to care.
• Serious memory loss, especially for personal events, photos, and shared moments.
• Difficulty with attention and impulse control, which can worsen underlying ADHD.
2/11
These are known consequences of long COVID and frontal‑lobe injury, not personality flaws. In other words: the “filter” and “control center” in her brain are damaged, so her inner intentions and her outward behavior no longer match the way they used to.
3/11
Read 11 tweets

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