We've headed from a false summit toward a larger peak in back-to-school transmission. Next week we'll know whether this is the largest or 2nd largest summer wave all-time. Expect 1.4-1.5 million daily infections at the peak.
This secondary peak is larger than anticipated previously, even when accounting for patterns of back-to-school transmission in prior years.
One, the West and South were peaking earlier, and the Northeast and Midwest have transmission picking up much faster than its falling off elsewhere. These are atypical regional differences.
Two, the 1-day isolation policy and general decline in school-based mitigation have unleashed transmission at higher levels than would be anticipated in prior years, even when accounting for the already-high levels of transmission as children went back to school.
Three, our model uses a combination of CDC and Biobot (former CDC contractor) data, using a 60% versus 40% mix for current case estimation. Biobot has not updated their data the prior two weeks without explanation. They were running much cooler than the CDC data, whether reflective of reality, or merely reporting delays. We have downgraded them to 20% in the model, and they will be downgraded further to 0% if they do not update their data this week.
You can take points 1 and 2 to account for the secondary and higher peak (shape of transmission), when models accounting for prior years would have suggested transmission slowing already, and point 3 accounting for a shift toward a slightly higher overall estimate of transmission.
PMC COVID-19 Forecasting Model, Sept 2, 2024
🧵2/8
This graph shows year-over-year transmission. It clarifies the unusual shape of the transmission distribution. A "peak" or false summit, followed by a very slight decline in transmission (negligible), then a 2nd (true) peak.
PMC COVID-19 Forecasting Model, Sept 2, 2024
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Presently, we estimate a peak at 1.4 million daily infections. Next week, we will have a much better sense. It could be in the 1.3-1.5 million range. There's about a 50% chance it will be the largest summer wave.
PMC COVID-19 Forecasting Model, Sept 2, 2024
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Happy Labor Day!
We're seeing higher transmission than during 91.6% of the pandemic, so COVID is very much not "over." In a gathering of 10 people of average risk, there would be a 1 in 4 chance someone has COVID if no special rules (testing, isolating, etc.).
Some schools still have not started yet and will begin tomorrow. Classrooms should presume someone has COVID. Mask, test, isolate until repeatedly negative.
PMC COVID-19 Forecasting Model, Sept 2, 2024
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Here's the heat map of transmission. You'll see a lack of a clear pattern because the South/West are slowing and the Midwest/Northeast are picking up.
Nationally, we see 1 in 35 people are actively infectious. The South is the highest with about 1 in 30 actively infectious.
PMC COVID-19 Forecasting Model, Sept 2, 2024
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Michigan (yellow line) has atypically low transmission. Happy to hear theories on this.
They have typically had unusual patterns of transmission. Perhaps the extended precautions during the 1st two years of the pandemic play some ongoing role.
About 0.9% are actively infectious in MI, about 1/3 the national average.
PMC COVID-19 Forecasting Model, Sept 2, 2024
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In the latest CDC data, 15 states have moderate to very high transmission.
🔹1 in 63 estimated actively infectious nationally, rising fastest in the Midwest & Northeast
🔹Very High: Indiana
🔹High: Nebraska, Vermont, Connecticut
🧵1/9
PMC estimates 1 in 26 people in Indiana are infectious and 1 in 39 in Connecticut.
MI, MS, and AR may have higher levels than shown due to poor reporting.
States AL to MS shown.
🧵2/9
PMC estimates 1 in 39 are infectious in both Nebraska and Vermont (coincidence, not typo).
Very few NY sites are reporting to the CDC, so use the NYS website there instead.
PMC COVlD Update, Week of Nov 24, 2025 (U.S.)
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With CDC data operational again, the transmission map is back. The data are always a week old, so transmission is likely worse than depicted.
We estimate 1 in 116 people actively infectious and 422,000 new daily infections.
PMC COVlD Update, Week of Nov 24, 2025 (U.S.)
🧵2/10
State level estimates are back. Note, the CDC changed their data processing approach in August, which tends to downplay transmission.
Does 1 in 45 in Indiana seem "moderate"?
Levels in MI may be mod/high (poor reporting).
PMC COVlD Update, Week of Nov 24, 2025 (U.S.)
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State-level estimates (continued).
Current levels may be much higher than noted here. Note that CDC data are always at least a week old. The 2nd half of November is a time period historically of accelerating transmission.
PMC COVID Update, Week of Nov 10, 2025 (U.S.)
1/6🧵
🔹301,000 new daily infections based on wastewater-derived models
🔹1 in 162 people (0.6%) actively infectious
🔹Levels the past 2 months corrected upward by Biobot
🔹"Lull point" estimated between Nov 5-21. Rising soon.
PMC COVID Update, Week of Nov 10, 2025 (U.S.)
2/6🧵
The central estimate of the forecast suggests we will surpass 500,000 new daily infections on Nov 22.
There's a 25% chance of a prolonged lull like last year. More likely, we are in wave territory by the end of the month.
PMC COVID Update, Week of Nov 10, 2025 (U.S.)
3/6🧵
We are presently in a lull between the 11th and 12th wave. Now is the time to get boosted and stock up on N95 masks, tests, and air purifier filters.
The relative "lull" in SARS-CoV-2 transmission is unlikely to go much lower.
✨1 in 209 people are estimated actively infectious, likely the lowest levels of 2025 nationwide.
Get boosted. Stock up on masks, tests, & filters.
PMC COVlD Update, Nov 3, 2025 (U.S.)
2 of 9 🧵
No data presently suggest the rise of a winter wave any earlier than "usual."
If following historical trends, transmission will pick up Nov 15-29. Last year's rise was atypically late.
PMC COVlD Update, Nov 3, 2025 (U.S.)
3 of 9 🧵
Expect rising misinformation/disinformation as transmission heats up:
🔹Abuse of community notes, particularly surrounding wastewater methodology
🔹Paid bot army attacks, especially about boosters & masks
Transmission typically accelerates in mid-November.
We are currently in a relative 'lull.' We estimate about a quarter-million new daily infections with 1 in 185 people actively infectious. Still bad, likely to get worse.
1/9 🧵
PMC COVlD Update, Oct 27, 2025 (US)
Our forecast through November 8 calls for flat transmission.
Nothing yet indicates the onset of a winter wave, but it would also be atypical for the lull to last much longer than another 2-3 weeks.
2/9 🧵
PMC COVlD Update, Oct 27, 2025 (US)
We estimate 264,000 new daily infections during this 'lull' period.
Biobot data have returned. Our substitute data from WWS last week correlated r=.97 (near perfect) with that, but Biobot did retroactively increase recent estimates.