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Emmanuel Profile picture
@ejustin46
Sep 6 • 15 tweets • 5 min read • Read on X
TOP 9 HIGH-RISK PLACES /Settings for SARS-CoV-2 TRANSMISSION !!!

From 2 recent studies :

▶️ Workplaces, especially open-plan offices
▶️ Long-distance public transport like trains and airplanes
▶️ Certain retail settings like convenience stores and takeaway delivery Image
2) ▶️ Car-pooling with relatives
▶️ Concerts, theaters, and indoor sports facilities
▶️ Bars and nightclubs, especially for those under 40 years old

In the 2nd study :
▶️ Prisons
▶️ Childcare centers
▶️ Long-term care facilities (LTCF). Image
3) TOP FACTORS to FACILITATE RAPID SPREAD of COVID-19

1st study :
▶️ Poor air ventilation
▶️ Close contacts
▶️ Maskless behavior

2nd study:
▶️ High population density and contact rates:
▶️ Vulnerable populations (childrens, residents LTCF, prisons ...) Image
4) ▶️ Delayed implementation of public health measures and low vaccination coverage

1st study
"Risk factors associated with the intensity of COVID-19 outbreaks in Canadian community settings: a retrospective analysis of outbreak-level surveillance data"
bmcpublichealth.biomedcentral.com/articles/10.11…
Image
5) 2nd study :
"Risk of SARS-CoV-2 infection in professional settings, shops, shared transport, and leisure activities in France, 2020–2022"


Thanks for reading 🙏 bmcpublichealth.biomedcentral.com/articles/10.11…
Image
6) YOU FORGOT the SCHOOL !

Thank you to everyone, who wrote me saying that I overlooked the schools. Although one of the studies does mention childcare, my summary focuses solely on what is presented in the studies and nothing beyond that 🤗

Here are some threads about schools
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15) Thanks to my wonderful followers for theirs comments 🙏

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More from @ejustin46

Emmanuel Profile picture
Sep 8
WHAT IS a PANDEMIC?
What affects ALL the AFFLUENTS ! 🤔

If the affluents, who live in well-ventilated homes, benefit from latest treatments, are not in their life, in close contact with a large number of people infected, and are largely unaffected—the pandemic is over.
Why ? Image
2) Etymologically, the term "pandemic" comes from the Greek words "pan" (meaning all) and "demos" (meaning the people).
The original meaning of "demos" referred to a very limited segment of the population in ancient Greece, the citizens who had the right to participate ... Image
3) ...in political affairs. This exclusion meant that not all residents of Athens were considered part of the demos; women, slaves, and foreign residents (metics) were denied citizenship and, consequently, a voice in decision-making. Image
Read 5 tweets
Emmanuel Profile picture
Sep 8
WHY does SARS-COV-2 VACCINATION PROVIDE LESS PROTECTION, for CERTAIN INDIVIDUALS?

The answer may be in the GUT MICROBIOTA
…nslational-medicine.biomedcentral.com/articles/10.11…
Image
2) This study investigated how the gut microbiome affects the durability and strength of antibody responses after COVID-19 vaccination. The researchers followed 44 healthy adults who received the BNT162b2 or ChAdOx1 vaccine, followed by a BNT162b2 booster. Image
3) They found that certain gut bacteria, like Faecalibacterium prausnitzii and Prevotella species, were linked to longer-lasting antibody responses after the initial vaccine doses. In contrast, Escherichia coli was associated with extended antibody levels in the ChAdOx1 group. Image
Read 6 tweets
Emmanuel Profile picture
Sep 7
WHEN HUMANS PRACTICALLY DISAPPEARED from the EARTH

Between 930,000 and 813,000 years ago, the POPULATION was REDUCED to only about 1,280 BREEDING INDIVIDUALS, bringing them close to extinction.
science.org/doi/10.1126/sc…
Image
2) The study used a new method to analyze human genetic data and found that our ancestors went through a severe population decline between 930,000 and 813,000 years ago. Image
3) During this bottleneck, the population was reduced to only about 1,280 breeding individuals, bringing them close to extinction. This ancient event coincided with a gap in the fossil record and may have been caused by major climate changes. Image
Read 4 tweets
Emmanuel Profile picture
Sep 7
REINFECTIONS which are MORE FREQUENT and occurring over SHORTER PERIODS 😨

journals.plos.org/plosone/articl…
Image
2) This study focuses on reinfections in Wales up to February 2022. We dare not imagine the current situation. Some interesting information:
▶️ The incidence rate of Omicron reinfections was 2.17 times higher than for Delta, after accounting for other factors. Image
3) This indicates an increased risk of reinfection with Omicron versus prior variants
▶️ The median time between first and second infections was shorter for Omicron (192 days) compared to Delta (226 days) reinfections.
Read 4 tweets
Emmanuel Profile picture
Sep 7
The OVERSIMPLIFICATION between VARIANT-SPECIFIC FITNESS GROWTH parameters, REPRODUCTIVE NUMBER and EPIDEMIOLOGICAL WAVES

with a key study of Trevor Bedford @trvrb 💯👍
journals.plos.org/ploscompbiol/a…
Image
2) This study offers crucial insights into the complex drivers of COVID-19 waves, moving beyond simplistic links between viral genetic changes and epidemiological trends. With rare transparency, it examines the limitations of using variant fitness alone to forecast viral spread. Image
3) The study looks at different statistical models that try to predict how the different variants of the COVID-19 virus will change over time. The models use data on the genetic sequences of the virus collected in different countries. Image
Read 10 tweets
Emmanuel Profile picture
Sep 6
ZOONOSIS and PANDEMICS (3)

A great article :
"Humans infecting animals infecting humans − from COVID-19 to bird flu, preventing pandemics requires protecting all species"
theconversation.com/humans-infecti…
Image
2) The interconnectedness of human, animal, and environmental health is crucial in preventing pandemics. The COVID-19 outbreak highlighted how pathogens can transmit between species, as seen with instances of human-to-animal transmission. Image
3) Research indicates that spillback, where diseases jump from humans to animals, poses significant risks, particularly to wildlife. An analysis of historical spillback events has shown a bias towards studying large mammals, neglecting smaller species. 4 Image
Read 4 tweets

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