Crémieux Profile picture
Sep 16, 2024 14 tweets 4 min read Read on X
I have a pretty major update for one of my articles.

It has to do with Justice Jackson's comment that when Black newborns are delivered by Black doctors, they're much more likely to survive, justifying racially discriminatory admissions.

We now know she was wrong🧵 Image
So if you don't recall, here's how Justice Jackson described the original study's findings.

She was wrong to describe it this way, because she mixed up percentage points with percentages, and she's referring to the uncontrolled rather than the fully-controlled effect. Image
After I saw her mention this, I looked into the study and found that its results all seemed to have p-values between 0.10 and 0.01.

Or in other words, the study was p-hacked. Image
If you look across all of the paper's models, you see that all the results are borderline significant at best, and usually just-nonsignificant, which is a sign of methodological tomfoolery and results that are likely fragile.

With all that said, I recommended ignoring the paper. Image
Today, a reanalysis has come out, and it doesn't tell us why the coefficients are all at best marginally significant, but instead, why they're all in the same direction.

The reason has to do with baby birthweights.
So, first thing:

(A) At very low birthweights, babies have higher mortality rates, and they're similar across baby races;

(B) At very low birthweights, babies have higher mortality rates, and they're similar across physician races. Image
Second thing: Black infants tend to have lower birthweights.

MIxed infants tend to birthweights in-between Blacks and Whites, and there's a mother effect, such that Black mothers have smaller mixed babies than White mothers (selection is still possible)

Third thing:

(A) Black babies with high birthweights disproportionately go to Black doctors;

(B) The Black babies sent to White doctors disproportionately have very low birthweights. Image
If you control for birthweight when running the original authors' models, two things happen.

For one, they fit a lot better.

For two, the apparently beneficial effect of patient-doctor racial concordance for Black babies disappears:Image
At this point, we have to ask ourselves why the original study didn't control for birthweight. One sentence in the original paper suggests the authors knew it was a potential issue, but they still failed to control for it.Image
PNAS also played an important role in keeping the public misinformed because they didn't mandate that the paper include its specification, so no one could see if birthweight was controlled. If we had known the full model details, surely someone would have called this out earlier.
Ultimately, we have ourselves yet another case of PNAS publishing highly popular rubbish and it taking far too long to get it corrected.

Let me preregister something else:

The original paper will continue to be cited more than the correction with the birthweight control.
The public will continue to be misled by the original, bad result. PNAS should probably retract it for the good of the public, but if I had to bet, they won't.

So people like Justice Jackson will continue to cite it to support their case for racial discrimination.
They'll continue doing that even though they're wrong.

To learn more and to find the article linked, check out my post on this: cremieux.xyz/p/missing-fixe…

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Crémieux

Crémieux Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @cremieuxrecueil

Jun 9
Because America has made the wise decision to compensate blood donors, it has ended up supplying some 70% of the world's blood plasma.

This is one of America's top exports, and each year, America saves hundreds of thousands of lives because it does this. Image
Some people argue against plasma donation on the basis of it being disproportionately used by poorer people

They say it's exploitative: they feel that selling something your body makes is wrong if disparate in ways they care about

But it's a lifesaver!

There's also research indicating that plasma donation can be healthy!

(And there's more indicating that, with compensation, it might reduce crime in the local area.)

Read 4 tweets
Jun 7
It's Pride Month, so let's talk about why San Francisco is so incredibly gay.

Military policy.

🧵 Image
In 1982, Randy Shilts published his biography of Harvey Milk, entitled "The Mayor of Castro Street".

For those who don't know, Harvey Milk was the first open homosexual to be voted into public office in the state of California.

He was on the San Francisco Board of Supervisors. Image
The biography contains a fair bit of background, not just about Harvey Milk, but about San Francisco's gay community more generally.

In its early years, San Francisco attracted large waves of mainly male migrants motivated by the promise of gold in California. Image
Read 18 tweets
Jun 1
My Uber driver says

- His license is suspended
- He was once a soldier for a Mafia family
- He's telling me about his time in Rikers
- He's showing me YouTube videos
- He's telling me his theories about Jews
He's telling me about gang wars he was in ad a kid.

He's wondering why all the Chinese girls are lined up - for an audition?

He says to go to Mother's Ruin for latin prostitutes.

All of this entirely unprompted.
"Yeah, these African guys, yeesh"

"I couldn't fuck that whore because I got the erectile dysfunction."

He just keeps going.
Read 6 tweets
May 29
This is just not true and it's sad that people believe it.

It's also indicting, when it's so obviously false if you just look out into the world. What you see should match what the statistics clearly show:

Estimated marriage effects for men and women are almost always similar🧵 Image
In that chart, I used the GSS and found something many people replicate:

1. Cross-sectionally, there's a relationship between being married and life satisfaction. It's similar for men and women.

2. Within persons—causally!—marriage boosts life satisfaction, but more for women.
Leveraging the same within-person design, we can use the Add Health dataset to look at stress and depression.

For both sexes, the effects are indistinguishable.

But they're also mostly not real: it's just that people who get married tend to be less stressed and depressed! Image
Read 10 tweets
May 26
As a recap on my appearance, Eli Lilly is pursuing:

- A one-dose drug for preventing most heart disease
- A vaccine for chlamydia
- A vaccine for gonorrhea
- A vaccine for Epstein-Barr
- A drug that lets you stay awake longer and feel more rested

It's a golden age of pharma! Image
And remember, Eli Lilly's big break historically was the University of Toronto licensing them to produce insulin.

They started off by giving it out for free, saving the world's diabetics at a time when there was no treatment available.

They've always been a force for good. Image
I think

- The heart disease drug will succeed
-- Will it commercialize? It can, easily. But I'm 50/50 due to the competition
- Chlamydia and gonorrhea vax will succeed, but I don't see much commercial potential with Lilly
- EBV vaccine will fail with Lilly, succeed eventually
Read 5 tweets
May 25
Eli Lilly has done it.

They've gone and made what seems to be a powerful, permanent gene therapy for LDL cholesterol.

That means they'll be able to effectively prevent most heart disease with a single infusion! Image
Almost all of the side effects were just things you see with any infusion. Some people react poorly to needles and having to sit for a while🤷‍♀️

And that's what we expect, because the people with good PCSK9 genes naturally are totally fine. This therapy catches the rest of us up!
This is amazing stuff, beating drug administration because it's permanent, and it only gets better from here.

We are going to get so healthy, so fast. Our grandkids are going to hear about heart attacks and have never actually seen one.

Source: nejm.org/doi/full/10.10…
Read 5 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(