Mike Hoerger, PhD MSCR MBA Profile picture
Sep 23, 2024 8 tweets 5 min read Read on X
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 1/8

The U.S. continues to see an estimated 1.1 million daily COVID infections with 2.2% of the population actively infectious as we descend from the peak of a 9th Covid wave.

Transmission will remain very high the rest of 2024.Main PMC figure showing Covid transmission over time. It shows 9 waves. The current wave peaked in August, and we're still seeing >1 million infections/day in the U.S.
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 2/8

Looking at the year-over-year graph, note that we're in uncharted territory for this point in the fall. Expect a very high "lull" in early November before the winter surge sets in.

As we have noted previously, our current estimates are likely slight underestimates given elevated school-based transmission and the CDC data standardization process.

Kids: They are smaller, and make smaller "contributions" to wastewater. Basically, it takes more sick kids to produce the average amount of wastewater virus to equate to an average infection (mostly in adults). This issue evens out over time, but it means the model may underestimate during back-to-school periods.

CDC: They describe the details of their process for standardizing data over time. It's very strong, much better than what most localized wastewater orgs or WWS do. It's a bit Dunning-Kruger to question basic wastewater scientists in doing the most fundamental components of their jobs, and the data continue to correlate >.90 with other metrics like Biobot. In comparing with other data, I take their estimates as spot on, but could also see arguments that they may underestimate transmission by 0-5%. It's something we always keep an eye on. Trust, but verify.

Transmission is magnitudes higher than much of the public realizes, so we focus on the big-picture view rather than quibbling over such issues that tend to balance out over time.

I hear @jlerollblues is considering weighting a model based on estimates of the proportion of infections in children. That's actually tougher to estimate than it sounds at first glance. You should key an eye on his models too and the work he and others are doing with the WHN.Estimating a "lull" the 1st week of November, but at an alarming 850k daily infections in the U.S.
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 3/8

Zooming in from the big picture, here's the past year of the pandemic.

🔹1.1 million daily infections
🔹Bimodal peak (Aug 10 & 24) of 1.3 million daily infections
🔹50-60% of transmission happens on the back end of waves

Continue to educate family, friends, and co-workers. Look at how the wave descends much more gradually than is arose. Many infections to come, and to try to prevent! Also, most people are not monitoring wastewater. They keep track of the cumulative "anecdata" of people they know sick or diagnosed with Covid recently. In their mind, the peak will feel like late October, when the cumulative count has really built up. You may find people more open to listening during the next month.Annual graph. Shows transmission much higher than a year ago at 1.1 million daily infections today, but nowhere near the 1.9 million daily infections of last winter's peak.   The wave is descending slower than it rose, which is a reminder than much transmission happens on the back end of waves.
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 4/8

These statistics document the ongoing toll of the pandemic.

🔥Expect about 29 million infections in the U.S. over the next month if the model holds.

🔥In a classroom of 30-35 people, there's about a 50% chance at least one person is infectious if weak/no isolation policies.

🔥Transmission is higher than during 80% of the pandemic.Current Levels for Sep 23, 2024 % of the Population Infectious 2.2% (1 in 45) New Daily Infections 1,059,000  New Weekly Infections 7,413,000  Resulting Weekly Long COVID Cases 371,000 to 1,483,000  Monthly Forecast Average % of the Population Infectious 2.0% (1 in 49) Average New Daily Infections 969,467 New Infections During the Next Month 29,084,000 Resulting Monthly Long COVID Cases 1,454,000 to 5,817,000  Running Totals Infections Nationwide in 2024 214,525,000 Average Number of Infections Per Person All-Time, U.S. 3.42  How Does Risk Increase with More Social Contacts? Number of peopl...
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 5/8

Three states stand out.

Estimated percentage of populations actively infectious:

Oklahoma: 8.9%
Oregon: 5.3%
New Hampshire: 5.3%

Note, estimates get less precise when focusing on smaller geographic units, and sometimes high estimates are revised in hindsight.

Also, while these figures may seem high, keep in mind that as one focuses on narrower units, the peak is more targeted, so local peaks see higher percentages than state peaks, which are higher than regional peaks, which are higher than national peaks. Smaller units have more leptokurtic transmission.CDC heat map. Very high transmission across most of the U.S.
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 6/8

These are the present regional estimates in the U.S.

The West is coming down from a second peak this wave but still with approximately 2.8% of the region actively infectious.

The Northeast region saw atypically low transmission this wave, relative to other regions. That area may see a different pattern of transmission than the rest of the U.S. the next several months. For example, within the northeast region, the winter peak could be larger than other areas. However, expect to also see more localized units where instead of 2 big waves (late summer and winter), there is 1 big wave in late Nov / early December, or a bumpy wave in the months ahead, like the west just saw. Last winter, we often posted examples of the "weird" transmission patterns in some areas.

I'd keep a closer eye on local data if in the Northeast region.Regional graph of transmission from the CDC.  Table from PMC  Estimated Percentage Actively Infectious National	2.2% (1 in 45) Northeast	1.2% (1 in 85) Midwest	2.4% (1 in 42) South	2.2% (1 in 45) West	2.8% (1 in 36)
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 7/8

Come join our team! I am accepting applicants for the Health Psychology PhD program at Tulane! 🎉

I'd love to work with someone passionate about research, cancer, & Covid safety. Should have a psych/similar background. 😷🧠Tulane University - Health Psychology PhD  Seeking applicants to our PhD program who Understand and are cautious about COVID, Have a background in psychology or a closely-related undergraduate or Master’s degree program, Plan to pursue a research-intensive career spanning multiple scientific disciplines, and Have a desire to help people with serious health conditions like cancer. Learn more: HealthPsychPhD.com or mhoerger@tulane.edu  Small images of a Tulane logo, a cancer ribbon, and a VFlex N95 mask
PMC COVID-19 Forecasting Model, Sep 23, 2024
🧵 8/8

Current state of the COVID-19 pandemic in the U.S.

🔹1.1 million daily COVID infections
🔹1 in 45 actively infectious
🔹High "lull" coming early November
🔹Winter surge to follow

Full dashboard: pmc19.com/dataDashboard has 6 sections, summarized in Tweets 1-6

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More from @michael_hoerger

Jul 2
🌍Want to track COVID transmission accurately worldwide?

This PMC thread walks you through leading dashboards with information more up to date than WHO & EU directories.

🧵 1/ World map, countries with high-quality up-to-date surveillance systems shown in blue.
The Pandemic Mitigation Collaborative (PMC) Dashboard provides weekly COVID updates for the U.S., using wastewater surveillance derived case estimation models and analytic forecasting.

We have added a list of international dashboards:
🧵 2/
pmc19.com/data/index.php…Australia: NSW Health Australia Department of Health, Western Australia Austria: Federal Government of Austria City of Vienna - Regional Coron-A Consortium Austria Czech Republic: State Health Institute Czech Republic Belgium: Belgian Institute for Health Canada: Government of Canada Andrew Young's Canada Visualization C19 Resources Canada * World Health Network (WHN) Canada **
Denmark: Statens Serum Institut Denmark Europe (multi-national): EU Wastewater Observatory Finland: National Institute for Health and Welfare Finland WHN Finland ** France: French Republic Data Airborne Risk Reduction Association (ARRA) France Zan Armstrong's France Visualization COVID Weather App France (Android, IOS, or Web) Thomas Delattre's France Visualization Germany: Infection Radar Germany Bay-VOC Bavaria Region Berlin Waterworks WHN Germany **
Hong Kong: Centre for Health Protection, Hong Kong Hungary: National Center for Public Health and Pharmacy of Hungary India: Pune Knowledge Cluster of India Gujarat Biotechnology Research Centre of India Ireland: Health Protection Surveillance Centre Ireland Japan: Japan Institute for Health Security Latvia: Institute of Food Safety, Animal Health and Environment Latvia Lithuania: National Public Health Centre of Luthuania Luxembourg: Microbs Luxembourg Netherlands: National Institute for Public Health and the Environment Netherlands WHN Netherlands ** New Zealand: New Zealand Institute for...
Slovenia: National Institute of Public Health Slovenia Spain: Government of Catalonia - Regional South Africa: National Institute for Communicable Diseases of South Africa South Korea: Korea Disease Control and Prevention Agency Sweden: Pathogens Sweden Switzerland: Swiss Confederation Federal Office of Public Health ETH Zurich Switzerland WISE Dashboard U.K.: Public Health Scotland Buckinghamshire Disability Service (BuDS) U.K.  *See the numbers 1-21 along the lower left. Click on 3-6 for national and regional data. ** Click on the dropdown menu. May need to try a different web browser.
Our international directory includes official government dashboards & those developed by citizen scientists.

We exclude countries that have stopped reporting in the past 2-12 months even if on EU or WHO lists. We also exclude low-quality data from opt-in testing programs.
🧵 3/
Read 43 tweets
Jun 24
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

🔥Biggest uptick since Jan
🔥1 in 167 actively infectious
🔥>2 million weekly infections
🔥700-1,200 resulting excess deaths from weekly infections

Track transmission closer to home w/our new state & international resources 👇

🧵1/6
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

🔹With >90% probability, we have entered the 11th COVlD wave.
🔹In a room of 50 people, there is already a 1 in 4 chance of an exposure.
🔹We expect nearly 15 million infections in the next month, and rising.

🧵2/6Current Levels for Jun 23, 2025	 % of the Population Infectious	 0.6% (1 in 167)	 New Daily Infections	 287000	 New Weekly Infections	 2009000	 Resulting Weekly Long COVID Cases	 100,000 to 402,000	 Resulting Weekly Excess Deaths	 700 to 1,200	 	 Monthly Forecast	 Average % of the Population Infectious	 1.0% (1 in 97)	 Average New Daily Infections	 493300	 New Infections During the Next Month	 14799000	 Resulting Monthly Long COVID Cases	 740,000 to 2,960,000	 Resulting Monthly Excess Deaths	 5,300 to 8,800	 	 Running Totals	 Infections Nationwide in 2025	 74869000	 Average Number of Infect...
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

We continue to expect transmission to break 500,000 daily infections in the U.S. around July 9th.

This is the same prediction as last week, as the forecast was dead on. Yet, there is considerably uncertainty around this timing.

🧵3/6Longitudinal transmission, past 12 months and 1-month forecast
Read 6 tweets
Jun 17
1) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Current transmission (red line) closely tracks that of summer 2023 (yellow line).

We expect to break 500k daily infections between July 9 and the end of July. Our current forecast...Year over year graph of tranmission
2) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Our current forecast is a bit more aggressive, predicting breaking 500k daily infections by July 9. The 2023 trend suggests end of July.

The 95% confidence interval shows large variation. Note that...Past 12 months of transmission (U.S.) and forecast
3) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Note that CDC and Biobot both had retroactive corrections to last week's data, meaning the relative "lull" will last a little longer than the uncorrected data suggested. No big news on NB.1.8.1.

All good news, but...10 pandemic waves. Soon 11
Read 7 tweets
Jun 16
1) Here's a quick example of how the federal government is censoring the best scientific research. It's not just cuts to ongoing research.

It's new grant submissions too... "No forbidden words found"
2) In January, I re-submitted a promising Covid/cancer grant to a non-federal funder. Hundreds of pages. Hundreds of hours of work. The best proposal I've submitted as a scientist.

Out of curiosity, I used Sean Mullen's Scan Assist tool to see how many banned words it had...
3) The proposal had 1,750 banned words. No big deal -- they're non-federal.

BUT I had planned to submit a smaller version to NIH this month as a "back up." Impossible!

It's not a matter of using a thesaurus or the find/replace command. The grant is on *Covid*... 1,750 banned words found
Read 13 tweets
Jun 9
1) PMC COVlD Dashboard, June 9, 2025

CDC wastewater surveillance data show transmission rising. This is our forecast if transmission growth follows typical patterns.

The high & low estimates could be thought of as optimistic & pessimistic scenarios for NB.1.8.1.Forecast graph: Rising transmission the next month
2) PMC COVlD Dashboard, June 9, 2025

Notice that current transmission (red line, lower left) tracks closely with two years ago (yellow), slightly below the median (gray), and not far below last year (orange).

Consider each of these trajectories realistic scenarios.Image
3) PMC COVlD Dashboard, June 9, 2025

All indications are that we are headed into the start of an 11th national wave in the U.S.

We could percolate near the lull point another couple weeks (fingers crossed), but that scenario is becoming less likely.Graph of 10 C19 waves
Read 7 tweets
Jun 3
1/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

National COVlD transmission recently fell to its lowest levels since the pre-Delta era.

It's go-time for many who have delayed medical appointments. The situation will likely get much worse in Jul/Aug.
2/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

An estimated 1 in 211 are actively infectious. Most states are "low" or "very low" per CDC.

The situation remains serious even in a relative "lull." >1.5 million weekly estimated infections to result in 600-900 excess deaths.C19 heat map
year over year graph, tracking closely with the median and past 2 years
Current Levels for Jun 2, 2025	 % of the Population Infectious	 0.5% (1 in 211)	 New Daily Infections	 227000	 New Weekly Infections	 1589000	 Resulting Weekly Long COVID Cases	 79,000 to 318,000	 Resulting Weekly Excess Deaths	 600 to 900	 	 Monthly Forecast	 Average % of the Population Infectious	 0.7% (1 in 139)	 Average New Daily Infections	 344566.6667	 New Infections During the Next Month	 10337000	 Resulting Monthly Long COVID Cases	 517,000 to 2,067,000	 Resulting Monthly Excess Deaths	 3,700 to 6,200	 	 Running Totals	 Infections Nationwide in 2025	 70132000	 Average Number of Infe...
Graph of the whole pandemic, 11th wave forthcoming
3/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

By the end of the month, we forecast an increase to 450k daily infections. If NB.1.8.1 takes off, closer to 600k. If overhyped, percolating only slightly higher.Past 12 months and forecast
Read 5 tweets

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