The U.S. continues to see an estimated 1.1 million daily COVID infections with 2.2% of the population actively infectious as we descend from the peak of a 9th Covid wave.
Transmission will remain very high the rest of 2024.
Looking at the year-over-year graph, note that we're in uncharted territory for this point in the fall. Expect a very high "lull" in early November before the winter surge sets in.
As we have noted previously, our current estimates are likely slight underestimates given elevated school-based transmission and the CDC data standardization process.
Kids: They are smaller, and make smaller "contributions" to wastewater. Basically, it takes more sick kids to produce the average amount of wastewater virus to equate to an average infection (mostly in adults). This issue evens out over time, but it means the model may underestimate during back-to-school periods.
CDC: They describe the details of their process for standardizing data over time. It's very strong, much better than what most localized wastewater orgs or WWS do. It's a bit Dunning-Kruger to question basic wastewater scientists in doing the most fundamental components of their jobs, and the data continue to correlate >.90 with other metrics like Biobot. In comparing with other data, I take their estimates as spot on, but could also see arguments that they may underestimate transmission by 0-5%. It's something we always keep an eye on. Trust, but verify.
Transmission is magnitudes higher than much of the public realizes, so we focus on the big-picture view rather than quibbling over such issues that tend to balance out over time.
I hear @jlerollblues is considering weighting a model based on estimates of the proportion of infections in children. That's actually tougher to estimate than it sounds at first glance. You should key an eye on his models too and the work he and others are doing with the WHN.
Zooming in from the big picture, here's the past year of the pandemic.
🔹1.1 million daily infections
🔹Bimodal peak (Aug 10 & 24) of 1.3 million daily infections
🔹50-60% of transmission happens on the back end of waves
Continue to educate family, friends, and co-workers. Look at how the wave descends much more gradually than is arose. Many infections to come, and to try to prevent! Also, most people are not monitoring wastewater. They keep track of the cumulative "anecdata" of people they know sick or diagnosed with Covid recently. In their mind, the peak will feel like late October, when the cumulative count has really built up. You may find people more open to listening during the next month.
Estimated percentage of populations actively infectious:
Oklahoma: 8.9%
Oregon: 5.3%
New Hampshire: 5.3%
Note, estimates get less precise when focusing on smaller geographic units, and sometimes high estimates are revised in hindsight.
Also, while these figures may seem high, keep in mind that as one focuses on narrower units, the peak is more targeted, so local peaks see higher percentages than state peaks, which are higher than regional peaks, which are higher than national peaks. Smaller units have more leptokurtic transmission.
These are the present regional estimates in the U.S.
The West is coming down from a second peak this wave but still with approximately 2.8% of the region actively infectious.
The Northeast region saw atypically low transmission this wave, relative to other regions. That area may see a different pattern of transmission than the rest of the U.S. the next several months. For example, within the northeast region, the winter peak could be larger than other areas. However, expect to also see more localized units where instead of 2 big waves (late summer and winter), there is 1 big wave in late Nov / early December, or a bumpy wave in the months ahead, like the west just saw. Last winter, we often posted examples of the "weird" transmission patterns in some areas.
I'd keep a closer eye on local data if in the Northeast region.
🌍Want to track COVID transmission accurately worldwide?
This PMC thread walks you through leading dashboards with information more up to date than WHO & EU directories.
🧵 1/
The Pandemic Mitigation Collaborative (PMC) Dashboard provides weekly COVID updates for the U.S., using wastewater surveillance derived case estimation models and analytic forecasting.
Our international directory includes official government dashboards & those developed by citizen scientists.
We exclude countries that have stopped reporting in the past 2-12 months even if on EU or WHO lists. We also exclude low-quality data from opt-in testing programs.
🧵 3/
🔥Biggest uptick since Jan
🔥1 in 167 actively infectious
🔥>2 million weekly infections
🔥700-1,200 resulting excess deaths from weekly infections
Track transmission closer to home w/our new state & international resources 👇
🧵1/6
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)
🔹With >90% probability, we have entered the 11th COVlD wave.
🔹In a room of 50 people, there is already a 1 in 4 chance of an exposure.
🔹We expect nearly 15 million infections in the next month, and rising.
🧵2/6
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)
We continue to expect transmission to break 500,000 daily infections in the U.S. around July 9th.
This is the same prediction as last week, as the forecast was dead on. Yet, there is considerably uncertainty around this timing.
Current transmission (red line) closely tracks that of summer 2023 (yellow line).
We expect to break 500k daily infections between July 9 and the end of July. Our current forecast...
2) PMC COVlD Dashboard, June 16, 2025 (U.S.)
Our current forecast is a bit more aggressive, predicting breaking 500k daily infections by July 9. The 2023 trend suggests end of July.
The 95% confidence interval shows large variation. Note that...
3) PMC COVlD Dashboard, June 16, 2025 (U.S.)
Note that CDC and Biobot both had retroactive corrections to last week's data, meaning the relative "lull" will last a little longer than the uncorrected data suggested. No big news on NB.1.8.1.
1) Here's a quick example of how the federal government is censoring the best scientific research. It's not just cuts to ongoing research.
It's new grant submissions too...
2) In January, I re-submitted a promising Covid/cancer grant to a non-federal funder. Hundreds of pages. Hundreds of hours of work. The best proposal I've submitted as a scientist.
Out of curiosity, I used Sean Mullen's Scan Assist tool to see how many banned words it had...
3) The proposal had 1,750 banned words. No big deal -- they're non-federal.
BUT I had planned to submit a smaller version to NIH this month as a "back up." Impossible!
It's not a matter of using a thesaurus or the find/replace command. The grant is on *Covid*...
CDC wastewater surveillance data show transmission rising. This is our forecast if transmission growth follows typical patterns.
The high & low estimates could be thought of as optimistic & pessimistic scenarios for NB.1.8.1.
2) PMC COVlD Dashboard, June 9, 2025
Notice that current transmission (red line, lower left) tracks closely with two years ago (yellow), slightly below the median (gray), and not far below last year (orange).
Consider each of these trajectories realistic scenarios.
3) PMC COVlD Dashboard, June 9, 2025
All indications are that we are headed into the start of an 11th national wave in the U.S.
We could percolate near the lull point another couple weeks (fingers crossed), but that scenario is becoming less likely.
National COVlD transmission recently fell to its lowest levels since the pre-Delta era.
It's go-time for many who have delayed medical appointments. The situation will likely get much worse in Jul/Aug.
2/ PMC COVlD Dashboard, June 2, 2025 (U.S.)
An estimated 1 in 211 are actively infectious. Most states are "low" or "very low" per CDC.
The situation remains serious even in a relative "lull." >1.5 million weekly estimated infections to result in 600-900 excess deaths.
3/ PMC COVlD Dashboard, June 2, 2025 (U.S.)
By the end of the month, we forecast an increase to 450k daily infections. If NB.1.8.1 takes off, closer to 600k. If overhyped, percolating only slightly higher.