The U.S. continues to see an estimated 1.1 million daily COVID infections with 2.2% of the population actively infectious as we descend from the peak of a 9th Covid wave.
Transmission will remain very high the rest of 2024.
Looking at the year-over-year graph, note that we're in uncharted territory for this point in the fall. Expect a very high "lull" in early November before the winter surge sets in.
As we have noted previously, our current estimates are likely slight underestimates given elevated school-based transmission and the CDC data standardization process.
Kids: They are smaller, and make smaller "contributions" to wastewater. Basically, it takes more sick kids to produce the average amount of wastewater virus to equate to an average infection (mostly in adults). This issue evens out over time, but it means the model may underestimate during back-to-school periods.
CDC: They describe the details of their process for standardizing data over time. It's very strong, much better than what most localized wastewater orgs or WWS do. It's a bit Dunning-Kruger to question basic wastewater scientists in doing the most fundamental components of their jobs, and the data continue to correlate >.90 with other metrics like Biobot. In comparing with other data, I take their estimates as spot on, but could also see arguments that they may underestimate transmission by 0-5%. It's something we always keep an eye on. Trust, but verify.
Transmission is magnitudes higher than much of the public realizes, so we focus on the big-picture view rather than quibbling over such issues that tend to balance out over time.
I hear @jlerollblues is considering weighting a model based on estimates of the proportion of infections in children. That's actually tougher to estimate than it sounds at first glance. You should key an eye on his models too and the work he and others are doing with the WHN.
Zooming in from the big picture, here's the past year of the pandemic.
🔹1.1 million daily infections
🔹Bimodal peak (Aug 10 & 24) of 1.3 million daily infections
🔹50-60% of transmission happens on the back end of waves
Continue to educate family, friends, and co-workers. Look at how the wave descends much more gradually than is arose. Many infections to come, and to try to prevent! Also, most people are not monitoring wastewater. They keep track of the cumulative "anecdata" of people they know sick or diagnosed with Covid recently. In their mind, the peak will feel like late October, when the cumulative count has really built up. You may find people more open to listening during the next month.
Estimated percentage of populations actively infectious:
Oklahoma: 8.9%
Oregon: 5.3%
New Hampshire: 5.3%
Note, estimates get less precise when focusing on smaller geographic units, and sometimes high estimates are revised in hindsight.
Also, while these figures may seem high, keep in mind that as one focuses on narrower units, the peak is more targeted, so local peaks see higher percentages than state peaks, which are higher than regional peaks, which are higher than national peaks. Smaller units have more leptokurtic transmission.
These are the present regional estimates in the U.S.
The West is coming down from a second peak this wave but still with approximately 2.8% of the region actively infectious.
The Northeast region saw atypically low transmission this wave, relative to other regions. That area may see a different pattern of transmission than the rest of the U.S. the next several months. For example, within the northeast region, the winter peak could be larger than other areas. However, expect to also see more localized units where instead of 2 big waves (late summer and winter), there is 1 big wave in late Nov / early December, or a bumpy wave in the months ahead, like the west just saw. Last winter, we often posted examples of the "weird" transmission patterns in some areas.
I'd keep a closer eye on local data if in the Northeast region.
🔹1 in 120 actively infectious
🔹1 in 3 chance of exposure in a room of 50
🔹2.8 million weekly infections
🔹>140,000 resulting LC cases from the week's infections
🔹>1,000 deaths resulting from the week's infections
2) Watch this video to understand how we use excess death data from one of the world's largest reinsurers to estimate how this week's infections will result in >1,000 deaths.
🔹800-1,400 deaths expected to result from this week's infections (new stat, see video next Tweet)
🔹100,000+ Long Covid conditions to result from this week's infections
🔹1 in 142 actively infectious today
🧵2 of 5
PMC Dashboard, March 31, 2025 (U.S.)
This video explains U.S. COVID excess death statistics, which we have incorporated into the dashboard.
🔥109,000-175,000 people in the U.S. are expected to die as a result of COVID in 2025, based on estimates derived from Swiss Re
🔥COVID deaths expected to be on par with lung cancer in the U.S. in 2025
🔥Death data added to the dashboard
2) Full video links to learn more about COVID #ExcessDeaths in the U.S.
🔹3 million new weekly infections in a persistent "lull" of substantial transmission
🔹1 in 107 (0.9%) of the population actively infectious
🔹1 in 3 regions in high/very high transmission (16 states and DC)
PMC Dashboard, Mar 24, 2025 (U.S.)
🧵2/5
We have had a steady state of about a half million infections the past several weeks. That's over 50 million estimated infections so far in 2025.
In a room of 40-50 people, there's a 1-in-3 chance of exposure if no testing/isolation.
PMC Dashboard, Mar 24, 2025 (U.S.)
🧵3/5
There's a good chance of steady transmission the next month. Often, we'd head into a low lull about now. BUT there are no universal precautions, immunity is waning from the fall & winter 2023-24, & viral evolution looks less 'lucky.'
It was before the pandemic declaration, before the federal government recommended masking.
COVlD spread quickly through New Orleans, leading to one of the highest mortality rates per capita in the U.S....
2) New Orleans service workers were disproportionately hit by the early pandemic. Many died. Many developed #LongCOVID at the time or have now through repeat infections. Many have switched to other sectors....
3) The sad fact is that many service workers are continuing to get #LongCOVID through repeat infections today because the pandemic is ongoing and many restaurants have high occupant density and horrendous air quality....