Vipin M. Vashishtha Profile picture
Sep 26 8 tweets 3 min read Read on X
A NEW nasal spray that trap & neutralize not only SARS-CoV-2, Influenza, RSV, Adeno & many other viruses & bacteria that are inhaled into the nose, immobilizing them until they die. The substance is >99.9% effective & contains no drugs 1/ Image
The FDA approved substance in the spray is known as the Pathogen Capture and Neutralizing Spray (PCANS), & contains no drugs of any kind.
Instead, the spray forms a gel that lines the inside of the nose. 2/ Image
While this gel doesn't affect the user's breathing, it does trap any viruses or bacteria that are subsequently inhaled into the nose, immobilizing them until they die. 3/ Image
In lab tests, the spray protected mice from a mouse-adapted form of the H1N1 influenza virus, even when that virus was administered at 25 times the lethal dose. 4/ Image
What's more, virus levels in the animals' lungs were reduced by over 99.99% as compared to an untreated control group of mice. The spray was retained in the rodents' noses for up to eight hours, and was effective at blocking infection for at least four hours. 5/
Although PCANS has yet to be tested on humans, it has been used in a 3D-printed model of a human nose, where it captured twice as many microbe-containing droplets as mucus alone. 6/ Image
It blocked and neutralized almost 100% of all viruses and bacteria we tested, including influenza, SARS-CoV-2, RSV, adenovirus, K Pneumonia and more. 7/
And if you suffer from allergies, take note – the researchers believe the spray could one day also be used on a daily basis to trap and neutralize allergens. 8/8

onlinelibrary.wiley.com/doi/10.1002/ad…

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More from @vipintukur

Nov 1
A NEW study, involving more than 200,000 adults, found that the COVID-19 pandemic caused a 29% increase in risk for developing dyslipidemia, a condition involving abnormal lipid (fat) levels in the blood 1/ Image
Seniors and people with type 2 diabetes were even more strongly affected, experiencing an approximately two-fold increased risk for developing dyslipidemia, which is a major risk factor for cardiovascular diseases such as heart attack and stroke. 2/
Given the extent of the pandemic, this increase in dyslipidemia risk is a cause for concern around the world. Researchers advise people to have their lipid levels monitored regularly and to consult with their HCP about ways to treat dyslipidemia, if detected 3/
Read 8 tweets
Nov 1
The human brain develops slowly compared to other animals. It takes almost 30 years, roughly half our average lifespan, to mature and refine its connections. A mouse brain, however, fully develops in just 5% of its lifespan. 1/
Researchers can now snoop on what happens inside millions of brain cells by cataloguing the genes, RNA and proteins they produce. And by studying brain tissue, scientists are learning key lessons about how the organ develops and functions. 2/
If there is one thing that stands out about the human brain compared with those of other primates — and even those of some extinct human relatives — it is its size. 3/ Image
Read 20 tweets
Oct 31
Researchers found that oral vitamin K2 supplementations reduces the frequency, intensity, & duration of nocturnal leg cramps (NLCs) in older individuals. 1/ Image
Approximately 50% to 60% of adults experience NLCs (Charley horse) in their lifetime, w/ ~20% encountering significant distress and insomnia that lead them to seek medical intervention.
There are no medical treatments without a substantial list of unpleasant side effects. 2/ Image
Patients orally took capsules containing either vitamin K2 (menaquinone 7), 180 μg, or a similar-looking placebo every day for 8 weeks. 3/
Read 6 tweets
Oct 30
Researchers reveal a powerful link between olfactory loss & inflammation in a staggering 139 medical conditions. This research emphasizes a little-known but potentially life-altering connection: the role our sense of smell plays in maintaining our physical and mental health 1/ Image
Olfactory dysfunction, often dismissed as a minor inconvenience, may actually be an early sign of various neurological and bodily diseases, as indicated by this research. 2/ Image
The data are particularly interesting because the researchers had previously found that olfactory enrichment can improve the memory of older adults by 226%. 3/ Image
Read 10 tweets
Oct 30
Why Covid19 vaccines failed to generate durable immunity?

We know Long lasting plasma cells (LLPC) in the bone marrow which derived from the memory B cells, are the key immune cell that provide longevity to vaccine induced protection. 1/ Image
While most vaccines generate memory B-cells, not all of them turn into LLPC. Special signals from B-cell receptors required for this to happen. Cross-linking between these receptors (BCR cross-linking) & the antigen present in the vaccine triggers the T-cells help 2/ Image
This BCR-cross linking and T cells help depends on the type of antigen in the vaccine, which is capable of triggering cross-linking & also dictates the creation of LLPCs. Live viral vaccines like MMR do this efficiently 3/ Image
Image
Read 12 tweets
Oct 27
Doctors in India are grappling to diagnose and treat unexplained and persistent symptoms of #LongCovid patients due to limited guidelines, whereas researchers have flagged inadequate studies on the condition. 1/ Image
While studies have suggested that about a third of those moderately or severely infected are likely to suffer from long Covid, region-wise though, incidence could vary. 2/ Image
A study estimated that 31% of the once-infected people in North America, 44% in Europe, and 51% in Asia, have #longCovid, which is challenging the healthcare system, but there are limited guidelines for its treatment 3/
Read 17 tweets

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