They gave animals on a "high PUFA diet" coenzyme q10 at 0.7 mg / kg bodyweight.
This dose is puny (7-8 mg human equivalent), and the "high PUFA diet" was under 5% PUFA, still way less than what the average person gets nowadays due to seed oils being in everything.
They showed that this tiny amount of CoQ10 could reduce DNA strand breaks.
This process increases with age - DNA damage is a known driver of cancer and a sign of overall oxidative stress.
This was an animal study done in a classic model of heart disease, the high cholesterol diet in rabbits.
This diet causes them to rapidly develop atherosclerosis since they naturally consume none of it.
They also compared light therapy to statin.
They used a polarized light with wavelengths in the 400-760 nm range, which is mostly red and near infrared light.
Polarization ensures all of the wavelengths are aligned properly, thought to have a more powerful biological effect.
Animals were given either 5 or 20 min per day of light therapy "on their outside surface of ear with 10 cm distance from lens every day
(10:00-12:00) for 8 weeks"
This system is in place to protect us against things like parasites and foreign toxins. It helps us eliminate them effectively before they cause even more damage.
The question is, what causes the increased production of these chemicals from these cells unnecessarily?
Why do some people’s immune cells release more of these mediators in response to things that are harmless like pollen?
#1 Gut health
Roughly 80% of your immune cells reside in the gut, and they are major players in your susceptibility to allergies.
Poor gut health can wreck your immune system's ability to properly deal with allergens in a few ways:
◈ Bad bacteria shift the balance of T cells away from an anti-inflammatory (regulatory) state to a pro-inflammatory one (Th2/Th17)
◈ Intestinal permeability exposes the immune system to more allergens by allowing "leakage"
◈ Inflammation / bacteria can stimulate innate lymphoid cells (ILC2 via IL-25, IL-33, TSLP), which activates eosinophils, mast cells and B cells to produce IgE
◈ The gut is the biggest source of histamine + serotonin in the entire body by far.
In fact, an animal study showed that you can literally give them allergies simply by giving them the gut bacteria of another animal who has allergies.
The animals with allergies mainly had higher endotoxin containing bacteria, which drive all sorts of inflammation in the gut and beyond.