Mike Hoerger, PhD MSCR MBA Profile picture
Nov 5, 2024 1 tweets 3 min read Read on X
PMC COVID-19 Forecasting Model, Nov 4, 2024

We're seeing an uptick in U.S. Covid transmission with 1 in 115 actively infectious.

The percentage of the population actively infectious has increased from 0.7% last week (based on updated data) to 0.9% this week.

The uptick is barring retroactive downward corrections.

We place the "lull point" as likely around Oct 20, but it could be +/- 2 weeks around that. Looking back at the late-summer wave, you'll see the date of the high point was quite arbitrary, and the same is true for the "lull."

There is presently considerable variation by region and even when examining the same region across different data sources. Some areas are still cooling off, while others are increasing markedly, as one would expect in the peri-lull area. There's also a lot of volatility across other data sources not included in our model (e.g., WastewaterSCAN up 43% nationally from Oct 18-25, but back down on the most recent data point on the 26th).

You'll note two updates in the current PMC forecasting model starting this week. These are described in detail in the technical appendix.

1) Biobot's sun rises again. 🌅 Our composite indicator of Covid transmission had been weighted 40% Biobot and 60% CDC. When Biobot abruptly stopped reporting for several weeks in a row during the summer wave, we were forced to downgrade them to 0% with no data coming in. After weeks of consistent reporting and a near-perfect correlation with recent CDC data (r=.95), we have re-included them in our current case-estimation model at 20% Biobot and 80% weight for CDC. Note, some of our pandemic "running total" estimates are marginally adjusted downward, as Biobot reported a slightly narrower (leptokurtic) late-summer wave. Having two high-quality data sources for estimating current transmission increases precision in real-time estimates and prepares for the eventuality that one source by experience a gap in reporting near the winter peak.

2) Best-Case and Worst-Case Scenarios. In figure 3 (upper right of dashboard), we have added 50% and 95% confidence bands. See the Technical Appendix for estimation details. Essentially, consider the 50% band (shaded area) the normal variation, and the boundaries of the 95% band (light dashed lines) the worst- and best-case scenarios, barring something nearly unforeseen (approximately 2.5% chance of a worse or better scenario). We encourage non-scientists to provide feedback on that figure, as it is challenging to present more detailed data in ways that are easily digestible. In Version 1 of the forecast (Aug 2023-Aug 2024), we reported several forecasting models and a compositive. It's unclear how helpful this was to readers, as we got surprisingly little feedback on it. With 15 months of forecasting, we now have the data to provide meaningful confidence bands. If helpful, we will keep it. If not, we will change the graphical depiction or replace them.

Info for new readers:

For those unfamiliar with the PMC model, find full weekly reports for the past 14+ months at pmc19.com/data

The models combine data from IHME, Biobot, and CDC to use wastewater to estimate case levels (r = .93 to .96) and forecast levels the next month based on typical (median) levels for that date and recent patterns of changes in transmission the past 4 weeks.

Our work has been cited in top scientific journals and media outlets, which are fully sourced in a detailed technical appendix at pmc19.com/data/PMC_COVID…

Examples include JAMA Onc, JAMA-NO, BMC Public Health, Time, People, TODAY, the Washington Post, the Institute for New Economic Thinking, Salon, Forbes, the New Republic, Fox, CBS, and NBC. See pgs 10-11 at the above link.Current Levels for Nov 4, 2024 % of the Population Infectious 0.9% (1 in 115) New Daily Infections 417,000  New Weekly Infections 2,919,000  Resulting Weekly Long COVID Cases 146,000 to 584,000  Monthly Forecast Average % of the Population Infectious 1.5% (1 in 65) Average New Daily Infections 735,033 New Infections During the Next Month 22,051,000 Resulting Monthly Long COVID Cases 1,103,000 to 4,410,000  Running Totals Infections Nationwide in 2024 227,349,000 Average Number of Infections Per Person All-Time, U.S. 3.46  How Does Risk Increase with More Social Contacts? Number of people | ...

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Mike Hoerger, PhD MSCR MBA

Mike Hoerger, PhD MSCR MBA Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @michael_hoerger

Jul 2
🌍Want to track COVID transmission accurately worldwide?

This PMC thread walks you through leading dashboards with information more up to date than WHO & EU directories.

🧵 1/ World map, countries with high-quality up-to-date surveillance systems shown in blue.
The Pandemic Mitigation Collaborative (PMC) Dashboard provides weekly COVID updates for the U.S., using wastewater surveillance derived case estimation models and analytic forecasting.

We have added a list of international dashboards:
🧵 2/
pmc19.com/data/index.php…Australia: NSW Health Australia Department of Health, Western Australia Austria: Federal Government of Austria City of Vienna - Regional Coron-A Consortium Austria Czech Republic: State Health Institute Czech Republic Belgium: Belgian Institute for Health Canada: Government of Canada Andrew Young's Canada Visualization C19 Resources Canada * World Health Network (WHN) Canada **
Denmark: Statens Serum Institut Denmark Europe (multi-national): EU Wastewater Observatory Finland: National Institute for Health and Welfare Finland WHN Finland ** France: French Republic Data Airborne Risk Reduction Association (ARRA) France Zan Armstrong's France Visualization COVID Weather App France (Android, IOS, or Web) Thomas Delattre's France Visualization Germany: Infection Radar Germany Bay-VOC Bavaria Region Berlin Waterworks WHN Germany **
Hong Kong: Centre for Health Protection, Hong Kong Hungary: National Center for Public Health and Pharmacy of Hungary India: Pune Knowledge Cluster of India Gujarat Biotechnology Research Centre of India Ireland: Health Protection Surveillance Centre Ireland Japan: Japan Institute for Health Security Latvia: Institute of Food Safety, Animal Health and Environment Latvia Lithuania: National Public Health Centre of Luthuania Luxembourg: Microbs Luxembourg Netherlands: National Institute for Public Health and the Environment Netherlands WHN Netherlands ** New Zealand: New Zealand Institute for...
Slovenia: National Institute of Public Health Slovenia Spain: Government of Catalonia - Regional South Africa: National Institute for Communicable Diseases of South Africa South Korea: Korea Disease Control and Prevention Agency Sweden: Pathogens Sweden Switzerland: Swiss Confederation Federal Office of Public Health ETH Zurich Switzerland WISE Dashboard U.K.: Public Health Scotland Buckinghamshire Disability Service (BuDS) U.K.  *See the numbers 1-21 along the lower left. Click on 3-6 for national and regional data. ** Click on the dropdown menu. May need to try a different web browser.
Our international directory includes official government dashboards & those developed by citizen scientists.

We exclude countries that have stopped reporting in the past 2-12 months even if on EU or WHO lists. We also exclude low-quality data from opt-in testing programs.
🧵 3/
Read 43 tweets
Jun 24
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

🔥Biggest uptick since Jan
🔥1 in 167 actively infectious
🔥>2 million weekly infections
🔥700-1,200 resulting excess deaths from weekly infections

Track transmission closer to home w/our new state & international resources 👇

🧵1/6
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

🔹With >90% probability, we have entered the 11th COVlD wave.
🔹In a room of 50 people, there is already a 1 in 4 chance of an exposure.
🔹We expect nearly 15 million infections in the next month, and rising.

🧵2/6Current Levels for Jun 23, 2025	 % of the Population Infectious	 0.6% (1 in 167)	 New Daily Infections	 287000	 New Weekly Infections	 2009000	 Resulting Weekly Long COVID Cases	 100,000 to 402,000	 Resulting Weekly Excess Deaths	 700 to 1,200	 	 Monthly Forecast	 Average % of the Population Infectious	 1.0% (1 in 97)	 Average New Daily Infections	 493300	 New Infections During the Next Month	 14799000	 Resulting Monthly Long COVID Cases	 740,000 to 2,960,000	 Resulting Monthly Excess Deaths	 5,300 to 8,800	 	 Running Totals	 Infections Nationwide in 2025	 74869000	 Average Number of Infect...
PMC COVlD Dashboard, Jun 23, 2025 (U.S.)

We continue to expect transmission to break 500,000 daily infections in the U.S. around July 9th.

This is the same prediction as last week, as the forecast was dead on. Yet, there is considerably uncertainty around this timing.

🧵3/6Longitudinal transmission, past 12 months and 1-month forecast
Read 6 tweets
Jun 17
1) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Current transmission (red line) closely tracks that of summer 2023 (yellow line).

We expect to break 500k daily infections between July 9 and the end of July. Our current forecast...Year over year graph of tranmission
2) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Our current forecast is a bit more aggressive, predicting breaking 500k daily infections by July 9. The 2023 trend suggests end of July.

The 95% confidence interval shows large variation. Note that...Past 12 months of transmission (U.S.) and forecast
3) PMC COVlD Dashboard, June 16, 2025 (U.S.)

Note that CDC and Biobot both had retroactive corrections to last week's data, meaning the relative "lull" will last a little longer than the uncorrected data suggested. No big news on NB.1.8.1.

All good news, but...10 pandemic waves. Soon 11
Read 7 tweets
Jun 16
1) Here's a quick example of how the federal government is censoring the best scientific research. It's not just cuts to ongoing research.

It's new grant submissions too... "No forbidden words found"
2) In January, I re-submitted a promising Covid/cancer grant to a non-federal funder. Hundreds of pages. Hundreds of hours of work. The best proposal I've submitted as a scientist.

Out of curiosity, I used Sean Mullen's Scan Assist tool to see how many banned words it had...
3) The proposal had 1,750 banned words. No big deal -- they're non-federal.

BUT I had planned to submit a smaller version to NIH this month as a "back up." Impossible!

It's not a matter of using a thesaurus or the find/replace command. The grant is on *Covid*... 1,750 banned words found
Read 13 tweets
Jun 9
1) PMC COVlD Dashboard, June 9, 2025

CDC wastewater surveillance data show transmission rising. This is our forecast if transmission growth follows typical patterns.

The high & low estimates could be thought of as optimistic & pessimistic scenarios for NB.1.8.1.Forecast graph: Rising transmission the next month
2) PMC COVlD Dashboard, June 9, 2025

Notice that current transmission (red line, lower left) tracks closely with two years ago (yellow), slightly below the median (gray), and not far below last year (orange).

Consider each of these trajectories realistic scenarios.Image
3) PMC COVlD Dashboard, June 9, 2025

All indications are that we are headed into the start of an 11th national wave in the U.S.

We could percolate near the lull point another couple weeks (fingers crossed), but that scenario is becoming less likely.Graph of 10 C19 waves
Read 7 tweets
Jun 3
1/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

National COVlD transmission recently fell to its lowest levels since the pre-Delta era.

It's go-time for many who have delayed medical appointments. The situation will likely get much worse in Jul/Aug.
2/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

An estimated 1 in 211 are actively infectious. Most states are "low" or "very low" per CDC.

The situation remains serious even in a relative "lull." >1.5 million weekly estimated infections to result in 600-900 excess deaths.C19 heat map
year over year graph, tracking closely with the median and past 2 years
Current Levels for Jun 2, 2025	 % of the Population Infectious	 0.5% (1 in 211)	 New Daily Infections	 227000	 New Weekly Infections	 1589000	 Resulting Weekly Long COVID Cases	 79,000 to 318,000	 Resulting Weekly Excess Deaths	 600 to 900	 	 Monthly Forecast	 Average % of the Population Infectious	 0.7% (1 in 139)	 Average New Daily Infections	 344566.6667	 New Infections During the Next Month	 10337000	 Resulting Monthly Long COVID Cases	 517,000 to 2,067,000	 Resulting Monthly Excess Deaths	 3,700 to 6,200	 	 Running Totals	 Infections Nationwide in 2025	 70132000	 Average Number of Infe...
Graph of the whole pandemic, 11th wave forthcoming
3/ PMC COVlD Dashboard, June 2, 2025 (U.S.)

By the end of the month, we forecast an increase to 450k daily infections. If NB.1.8.1 takes off, closer to 600k. If overhyped, percolating only slightly higher.Past 12 months and forecast
Read 5 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(