Lazarus Long Profile picture
Nov 5 14 tweets 6 min read Read on X
Influenza D. Ever hear of it?

You've heard of Influenza B being wiped out by masking, etc used for C0V1D protections.

You've heard of #H5N1, bird flu, which is Influenza A

Influenza D Virus ( IDV) - a thread on airborne flu. Because it is airborne. H5N1-infected cows are still being piled on the side of the road, though most producers keep their dead piles off the road and hidden from public view.   This was outside Vaca Linda dairy in Hanford, California, yesterday and I did confirm with the producer that his herd was
IVD IS NOT H5N1!

But it has lessons for us. The bodies of cattle are lining the roads in dusty California dairy communities, killed off by H5N1, and an obstinate USDA who says that it is NOT airborne.



October 3, 2024: tinalexander.github.io/notes/2024/10We know that it is not respiratory. We do know that it is associated with milk. We believe that milking equipment, and other environmental surfaces or milking practices are implicated, but it is challenging to get the definitive answer that we want, even as we continue to explore that we do know the best way to address that.  And that is to make sure that folks understand the risk to their herd, and are able to implement biosecurity, in order to mitigate the risk of the spread.
Turns out that IVD is an airborne flu, too.

The following is from this study:


IVD was discovered only in 2011 in a pig, but had been circulating since 2003. It is not known where it came from, but seems mostly to be in cows - although other species pmc.ncbi.nlm.nih.gov/articles/PMC64…Pathogenesis, Host Innate Immune Response, and Aerosol Transmission of Influenza D Virus in Cattle
can get it.

They set up a transmission experiment which the USDA has not seen fit to duplicate, @RickABright.

Control animals upwind.

They infected all 8 of the calves in the big bunch with aerosols. (A) Experiment timeline and sampling. D0 is the day of inoculation. (B) Fourteen naive calves were allocated to two separated pens, one with 5 mock-infected calves (control group) and the second with 11 calves. In the latter pen, calves were divided into two groups separated by steel panels, 3 m apart. Eight calves (direct-inoculated group) were inoculated at day 0 (D0) with 107 TCID50 of IDV 5920, while the three others (aerosol-sentinel group) were not, in order to evaluate the aerosol transmission of IDV.
(A) Experiment timeline and sampling. D0 is the day of inoculation. (B) Fourteen naive calves were allocated to two separated pens, one with 5 mock-infected calves (control group) and the second with 11 calves. In the latter pen, calves were divided into two groups separated by steel panels, 3 m apart. Eight calves (direct-inoculated group) were inoculated at day 0 (D0) with 107 TCID50 of IDV 5920, while the three others (aerosol-sentinel group) were not, in order to evaluate the aerosol transmission of IDV.
Image
Eight. EIGHT! The more bodies infected means that the more aerosols are being generated.

So, I was not surprised to read that one of the downwind, 9 feet away, cows got infected by Day 8, 9, or 10.

Then the other two downwind cows got infected between Day 16 and 20. Our study demonstrated that the efficient transmission of IDV infection via aerosol to a seronegative calf can occur under experimental conditions and that IDV is an airborne transmitted pathogen. The first aerosol-sentinel calf began to shed virus actively at D11. Considering an incubation period of 1 to 3 days (direct-inoculated group), this calf may have been infected between D8 and D10, when IDV excretion in the direct-inoculated group remained high. For the two other aerosol-sentinel calves, we can estimate the infection period between D16 and D20, at the period of highest excretion of...
Image
They ALSO sampled the air, and found it there, as well.

We have no idea of the ACH, or the speed of the wind - it's not in the study. . To investigate aerosol transmission, we performed virus detection in 24 air samples collected over the course of the experiment in the aerosol-sentinel calves’ area, the separating space, and the direct-inoculated calves’ area. The IDV genome was detected in air samples from the three locations at D3, D5, D7, D9, and D13 in a range of 5.2 to 6.1 log10 RNA copies/m3 of air (Fig. 4C), with a maximum between D5 and D7. IDV detection started at D3 in the direct-inoculated group area and D5 in the separating space and aerosol-sentinel group area. After D9, IDV was detected only in aerosols of ...
Now, let's take a look at the USDA aerosol vs. study.

They put the aerosol nose halters on, and all 4 were infected via aerosols. That's it.

No mini-herd. No sentinel animals.

Just an aerosol shaker, and OMG! Look how viral the milk is over there

biorxiv.org/content/10.110…
where we jammed a catheter up the cows' teat to infect them in a completely natural way.

Obviously, I am being sarcastic.

But in a write-up by the USDA on this study, we find the USDA citing it as proof that it is not airborne.

They also cited
ars.usda.gov/news-events/ne…
unpublished data.

@Alexander_Tin @amymaxmen @susrust - there might be a story there.

This was shared on July 29, 2024, when there were 14 human cases, 172 farms, 12 states.

We are now at 44 human cases, 442 farms, 15 states

What unpublished data does the USDA have? Image
Image
There is context here. In the beginning of the ongoing C0V1D pandemic, Dr. John Conly of the WHO said that it was not airborne thanks to unpublished data he had, in an online debate with @DFisman and @prather_kim.

It turned out to be bad data. An email chain.

But, at the
time, it was taken seriously. Conly went on to cite it in a couple of studies.

We have examples of how to properly do an airborne transmission study in cows, let me spell it out for the USDA.

Why not duplicate the eight cows with 3 sentinel cows? But have all of the cows be
lactating.

If the 3 sentinel lactating cows get infected and their mammary glands light up with virus? There we go.

Like measles where we inhale it, but exhibit it on our skin, we would know that it is inhaled - and then viremia (temporary blood infection) leads to mammary
gland infection.

And air sample like crazy.

How is it the USDA hasn't studied milk aerosols?

Where is their sense of urgency?
One more thing....They could have one more group. Separated by two grills allowing air through, but not cow tongues - testing near field aerosols. Very close together.

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Lazarus Long

Lazarus Long Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @LazarusLong13

Nov 6
America just voted for a whole bunch of non-empathic choices.

Voted for TFG.

Why?

COVID could be part of the answer.

You see, the anterior insular cortex contains our empathy.

. mountsinai.org/about/newsroom…Image
"The insula and anterior cingulate cortex are often coactive during functional neuroimaging tasks of emotion and empathy."
And both are damaged by Covid.

pmc.ncbi.nlm.nih.gov/articles/PMC92…In agreement with the frequent impairment of smell and taste in COVID-19, they found greater atrophy and indicators of increased tissue damage in the anterior cingulate cortex, orbitofrontal cortex and insula, as well as in the ventral striatum, amygdala, hippocampus and para-hippocampal gyrus, which are connected to the primary olfactory cortex
Read 6 tweets
Nov 2
Chicken Soup for C0vid? Think it's ridiculous?

🧵. Chicken soup for Covid.  Not for the soul because the CDC is sucking the essence of that with their FUCKING policies
It's from this October 29, 2025 story on Fox News, about the alarm that the CDC and parents are expressing over the rise of respiratory diseases in preschool age children.

PRESCHOOL AGE CHILDREN.

foxrgv.tv/unprecedented-…Unprecedented Rise in Respiratory Illnesses among Children: The CDC Raises Alarm
On October 18, 2024, the CDC published an alert that Mycoplasma pneumoniae, walking pneumonia, has been high since late spring.

The wee tykes are too young to have been affected by the horrors of immune system deprivation caused by masking.

cdc.gov/ncird/whats-ne…https://www.cdc.gov/ncird/whats-new/mycoplasma-pneumoniae-infections-have-been-increasing.html
Read 11 tweets
Oct 31
An interesting way to get stunning dry rub on (off) transfer of any design onto your boring white N95.

As always fit test after.

Need a laser jet printer.
These types of label sheets.

a.co/d/8kDUKMJ

How-to:
youtu.be/TWmUo5fkSt4?si…
This would be excellent on an N95.

Do you think Bonnie Henry would like this, @amandalhu ? Wash hand logo.
@amandalhu Fun for this time of year. I voted sticker.
Read 5 tweets
Oct 29
#EBVis airborne update.

EBV found in air sampling directly from the lungs.

webthesis.biblio.polito.it/17636/46.8% observed using nasal swabs; Carpagnano et al. [37], on the contrary, we were able to detect Epstein-Barr virus (EBV) and Citomegalovirus (CMV) DNA in the EBC with real-time PCR assay, two viruses which are indicative of lung cancer, if are present in the respiratory tract; the results obtained with EBC analysis have comparable sensitivity and specificity of the results obtained with the bronchial brushing fluid samples analysed with the same essay; with the EBC analysis, it was also possible to evaluate the presence of HPV DNA in the respiratory tract and the results were perfectly ov...
Found in air sampling from airplanes - despite the HEPAs.

Huge study from THE Jet Propulsion Laboratory.

With a total of 4 downloads.

You are now an elite member of a very, very exclusive Air orne Knowledge Club.

dataverse.jpl.nasa.gov/dataset.xhtml?…As shown in Figure 4.1-1, samples collected aboard Flight 2N yielded no detectable viruses above the lower threshold (375 virion copies).  However, samples from flight 2-R-N demonstrated low and persistent, but barely detectable levels of VZV and EBV (Figure 4.1-2).  Coronavirus was also detected, but the levels were below the reliable range of detection. For flights 3-L and 3R-L, there were scarce levels of VZV, most of which was below the reliable limit.  Sample 3R-L-9 was the only sample from these two flights having a detectable level of EBV (Figure 4.1-4).  Coronavirus was not found in...
Jet Propulsion Lab page..
Inevitably, some silly IPC person will discover this thread, @BarryHunt008, and whine about RNA, visible virus being cultured.

Which is interesting.

PCR is good enough for swabbing.

But not for air?

Despite aerosol expert after aerosol expert telling In clinical diagnostics, the use of PCR for  diagnosing the presence of a causative agent has been well established and is in routine use in clinical diagnostics for various diseases, e.g. encephalitis (such as herpes simplex, varicella zoster, enterovirus, human herpesvirus 6, West Nile virus and JC virus, to name but a few) and blood-borne virus infections (such as with hepatitis B, hepatitis C, cytomegalovirus and Epstein-Barr virus, dengue virus and HIV), without the requirement to demonstrate independent viral viability in each case before a diagnosis is made and any necessary treatmen...
Read 4 tweets
Oct 28
Getting closer to 1918, folks.

Scientists isolated #H5N1 from the eyes of a dairy worker, and it efficiently infected alveolar epithelial cells.

Those alveoli cells are deep in your lungs, and are the primary
location where the smallest aerosols end up being inhaled to.

It infected LESS EFFICIENTLY in corneal epithelial cells. The eyeballs.

A/Texas/37/2024 (huTX37-H5N1) is the technical name.

Did you know ferrets are a great respiratory model for us humans?
So, seeing it kill 5 of 6 ferrets?

Not good. Despite causing mild disease in the infected worker, huTX37-H5N1 was lethal in mice and ferrets and spread systemically with high titres in respiratory and non-respiratory organs. Importantly, in four independent experiments in ferrets, huTX37-H5N1 transmitted via respiratory droplets in 17%–33% of transmission pairs and five of six exposed ferrets that became infected died.
Read 6 tweets
Oct 28
Rest for 6-8 weeks after getting C0VID to help yourself avoid LongCovid.

I wanted better resources on this, so went digging.
This is not a new idea.

Mono comes from Ebstein Barr Virus (and other).

There is a long history of doctors recommending rest for 6-8 weeks to avoid relapse.

C0vid infects even more of the body than EBV. ✅

uclahealth.org/news/article/i…

mayoclinic.org/diseases-condi… Refrain from vigorous activities: Because mono can affect the entire lymph system, including the spleen (located under your left lower rib cage), avoid vigorous activities such as football, soccer or running. Do not play contact sports until at least 6-8 weeks after diagnosis or onset of symptoms. You can do mild exercises such as walking or swimming, as long as the activity doesn't increase fatigue.
Wait to return to sports and some other activities Most signs and symptoms of mononucleosis ease within a few weeks, but it may be two to three months before you feel completely normal. The more rest you get, the sooner you should recover. Returning to your usual schedule too soon can increase the risk of a relapse.
EBV is a trigger for Chronic Fatigue Syndrome (ME/CFS)

sciencedirect.com/science/articl…

Associated with ME/CFS
nature.com/articles/s4159…
Read 9 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(