Josh Wolfe Profile picture
Nov 23 17 tweets 7 min read Read on X
1/ New Lux quarterly letter to LPs...

Our theme? Tech, venture, global markets told in...

...Four parables of Four brothers
1 Prometheus
2 Menoetius
3 Epimetheus
4 AtlasImage
2/ The The Prometheus Promise––is Extending Human Limits what we call extensionalism

technology is not just augmenting our natural senses, but fundamentally extending and transforming them inImage
Image
3/ From sight, sound, touch, hearing and now…smell.

Technology extends our senses (“extensionalism”) with many Lux family co’ leading the way from

@physical_int + CTRL-Labs + Auris Surgical Robotics (touch)
@EikonTX + @Matterport (sight)
Chromatic (hearing)
@Osmo_Labs (smell)Image
4/The lever + pulley of antiquity gave way to the steam shovel + excavator

Even the modern state's quest for legibility––what James Scott (Seeing Like a State) saw as drive to make complex systems measurable + manageable––Lux cos extend sensed in sea + space @saildrone @planetImage
@physical_int @EikonTX @Matterport @Osmo_Labs @saildrone @planet 5/ From genetically modified pigs with life-saving organs successfully transplanted into humans in dire need with no alternatives…

…to AI infrastructure with important 2nd order effects underway…. Image
@physical_int @EikonTX @Matterport @Osmo_Labs @saildrone @planet 6/
Today's largest Al clusters use around 100,000 Nvidia H100 chips and consume roughly 100 megawatts of power. Next year's clusters will scale to 300,000-500,000 chips requiring nearly a gigawatt of power — about the consumption of a small city. Image
7/ we see 2 futures emerging

1 Distributed compute can eliminate need for massive monolithic clusters––as per our investment in @togethercompute

2 As industry fixates on bigger data centers + more powerful chips––Apple quietly has showing how to run models directly on devices w/ limited memoryImage
8/ America only has a handful of locations that can provide the gigawatt-scale power these massive clusters will require.

While we're bullish on the seeming resurgence of elemental energy - our rebrand of nuclear––abundant natural gas from the Texas Permian seems a wiser bet.Image
@physical_int @EikonTX @Matterport @Osmo_Labs @saildrone @planet @togethercompute 9/ NYC's emergence as a major Al hub with 20 new unicorns in 2023 and 10 more already in 2024.

BUT…beneath the surface excitement though, we identified critical insights that are grounding our investment approach from the irrationality of the markets Image
10/ Epimetheus represents the danger of divorcing motivation from consequence. The benefits of the future start with tradeoffs of the present constrained by decisions of the past.

Higher for longer is our posture on the natural cost of capital, regardless of what the Fed does.Image
@physical_int @EikonTX @Matterport @Osmo_Labs @saildrone @planet @togethercompute 11/

We have 4 main strategies for current market:

1 Lux Labs
2 Corporate Spin-offs (globally)
3 Tactical Global Opportunities
4 “Fixware” (aka maintenance) (globally) Image
12/ While techno-optimists focus on frothy greenshoots, they're missing the industry's further desertification: over 30% of 50,000 private cos are trapped in late-stage limbo while >730 unicorns are trapped in exit-less purgatory, with nearly 50% over 10yrs old + dragging down returns like sea-sinking anchors…Image
13/ We are particularly excited about Lux Labs

14/ Lux Labs formalizes our nearly twenty-year track record of transitioning breakthrough science from the laboratory to the marketplace.

We have successfully spun out or have been first investors behind de-risked technologies and teams from big tech. Examples include Osmo and Physical Intelligence from Google, Aeva (and another not yet disclosed) from Apple, and Evolutionary Scale from Meta. These unlock value by giving breakthrough teams and technologies the funds, freedom and focused entrepreneurial attention to thrive.Image
@physical_int @EikonTX @Matterport @Osmo_Labs @saildrone @planet @togethercompute 15/
Globally we are particularly excited about Israel + Japan +UK
🇮🇱🇯🇵🇬🇧 Image
@physical_int @EikonTX @Matterport @Osmo_Labs @saildrone @planet @togethercompute 16/ Image
17/ As we look to the remainder of 2024 and beyond, several trends bear watching:

the acceleration of Al capabilities beyond language models into biology, chemistry and physical systems; the growing imperative for domestic manufacturing and supply-chain resilience; the continued convergence of commercial and defense technology; the evolution of experimental science through automation; and finally, the transformation of healthcare through sci-fi breakthroughs like xenotransplantation.

In the end, we return to where we started: compassionately competitive, motivated and mission-driven, helping to write the future, one breakthrough at a time.

We're betting on the impatient optimists who refuse to wait for permission to build the future.Image

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More from @wolfejosh

Nov 18
1/ 🏦 America needs an experienced wise and smarter than other global finance heads so he can outsmart them––a Treasury Secretary who puts 🇺🇸 first.

A leader who gets tariffs, trade, & turning the tide back in our favor.

SCOTT BESSENT is definitely THAT guy.

Here’s why: 🧵
2/ Scott understands tariffs aren’t just a policy—they’re a POWER MOVE.

While others talk, Scott will make sure unfair trade practices PAY UP.

He’s about winning for American workers and businesses.
3/ His America First agenda isn’t just talk

Scott’s built relationships across the globe, not to placate but to DOMINATE

He knows our adversaries + allies––they respect him.

He knows how to leverage deals to bring foreign $$ into the U.S. & keep it flowing into OUR economy💪
Read 9 tweets
Nov 17
1/ 🛡️ The FUTURE of WARFARE isn’t a “revolution” but an evolution—a mix of drones, AI, and smart strategy. What’s the playbook for Taiwan, Ukraine, and beyond?

A quick high-level dive📡Image
2/ 🛰️ The Gulf War heralded stealth, precision, & GPS.

Today, uncrewed systems (drones) + AI define the battlefield. But there are limits. Attrition wars teach hard lessons. Image
3/ 🔥 UKRAINE's lessons for TAIWAN:

Drones disrupt but aren’t invincible.

Customized kamikaze drones carry ~5kg payloads, fly ~19km + force adversaries to spend $$$ on defense.

Cheap beats fancy (sometimes). Image
Read 12 tweets
Jun 25
Some (first in history) news tomorrow…
2/ More than 3.5 billion years ago, life on Earth emerged from chemical reactions.

Nature invented RNA, proteins, and DNA, the core molecules of life, and created the ribosome, a molecular factory that builds proteins from instructions in the genome.
3/ Proteins are wondrous dynamic molecules with incredible FUNCTIONS

-molecular engines powering motion
-photosynthetic machines capturing and converting to energy
-scaffolding building skeletons of cells
-complex sensors interacting with environment
-information processing systems running the programming operating system of life
Read 22 tweets
May 21
1/ Quick thread 🧵important new paper 📜from @sfiscience on the THERMODYNAMICS of COMPUTATION...

Ever wondered why your gadgets get warm after using them for a while? As with cells🧫, brains🧠 and laptops💻––it's all about energy use and heat🔥.... Image
2/ The key is "stopping times". In biology a cell might stop making a protein once it triggers a reaction from another cell. In simulations like a coin-flipping it may be once it reaches a set number of flips...Image
3/ Estimates are that computers use 5-9% of global energy (AI will only increase this📈). Biological systems on the other hand are 100,000x more energy-efficient...
Read 6 tweets
May 19
1/ NEW–– just released.

Lux Q1 2024 Letter to LPs… Image
2/ Themes:

1. Riskgaming
2. Possible adjacencies + the ADJACENT POSSIBLE
3. Build your cash position for tuck-in M&A
4. Prepare for rising cost of capital (and a lot less of it)…
5. Moravec Paradox––what’s easy is hard and what’s hard is easy Image
3/ Lux family companies including @anduriltech , @SakanaAILabs, @togethercompute, @VardaSpace, @AppliedInt have raised war chest balance sheets…

watch for rising cost of capital, more powerful labor unions… Image
Read 8 tweets
Mar 27
1/ We lost a brilliant, accomplished, self-effacing, humble, kind, compassionate, truth-seeking HUMAN certain only of uncertainty, child like wonder cataloging our fallabilities

I last had dinner with Danny some weeks back (we talked about...
washingtonpost.com/obituaries/202…
2/ We ate🍽 at brilliant friend+ 🎬artist (Moneyball, Capote, Foxcatcher) Bennett Miller's apt + talked ketamine & psychedelics (Danny had done), the pain of conflict in the mideast**, how both free will + consciousness were in Danny's POV total illusions even if useful ones Image
3/ At dinner a friend asked Danny (Israeli) how he was + he answered

The friend thought he said "I'm partly I'll at ease"
And asked "why partly?"
Danny said "huh?"
Friend repeated: "you said you were partly ill at ease"
Danny smiled: "No. I said part of me is in the Middle East"
Read 11 tweets

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