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Dr Clare Craig Profile picture
@ClareCraigPath
Dec 9, 2024 • 25 tweets • 8 min read • Read on X
Scrolly
Today saw the release of minutes for the working group set up to advise MHRA on the covid vaccines.

They knew the issues but ignored them...🧵
On 27th November they briefly discussed a lack of any potential benefit for the under 50s but quickly concluded that there was a favourable risk/benefit for anyone aged over 16 years!

assets.publishing.service.gov.uk/media/67503fbc…Image
They made the case that the already infected should be injected because of lack of evidence of risk!

What about the fact they didn't need it! Image
They noted issues with early batches. Image
These were process 2 batches - not the bespoke process 1 batches given in the trial.

"it is not currently feasible to compare these two batches to those given to subjects in clinical studies." Image
"it may be the case that the batches the FDA are evaluating are further along the development lifecycle than those allocated for the UK"
The meeting ended with a reminder to put profits ahead of public health.

They reconvened the next day. Image
That evening they were told that they were to assess to worse batches.

For one they noted visible particulate matter in the vials.

They noted that another had degraded mRNA.
assets.publishing.service.gov.uk/media/67503fbc…Image
The batch with floaters in it was the infamous EJ0553.

This was used in the trial resulting in a 13 fold higher incidence of lymphadenopathy compared with trial doses. Image
These were "rejected vials" and they had not done a potency test. Image
Don't worry - the particles "disappear after the product is diluted"!

Also they "were not understood to be associated with a change in concentration of RNA containing LNPs" - but no measurement to confirm this! Image
It was a problem at the "end of the filling line" - i.e. it was from the dregs of the barrel. Image
Nucleic acids clump and lipid nanoparticles float - both could result in a higher concentration of product in the last batches to be filled.
The manufacturer admitted "no IPCs [in-process controls] or visual inspection is performed during the manufacturing process until after filling" Image
There was no data on the process 2 batch performance in humans and no stability data either - both were extrapolated from process 1 in the trial. Image
Barely any testing on stability. Image
And evidence that the RNA was degraded. Image
They ended with a request for more data on the particles. Image
Three days later Lord Bethel signed off on the drug.

A week after that injections began.
dailymail.co.uk/news/article-1…
They returned on 7th December - the day before injections began.

PHE were looking at serology (antibody levels in blood) in individuals that "have been vaccinated." Who are these people injected before 8th December? Image
They had not had the answers they requested on stability.

They detail all the issues then say - let's release the batches! Image
What on earth is redacted here? Image
The rest of the minutes that day were about AZ and Moderna.

No futher comment about the Pfizer batches that were going to be injected into people from the next day.
assets.publishing.service.gov.uk/media/6750518f…
Distribution was acknowledged as being all over the body. assets.publishing.service.gov.uk/media/6750518f…Image
The RNA was worse that the CT = clinical trial batches.

The batches in use had a "higher potency".

assets.publishing.service.gov.uk/media/6750518f…Image

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More from @ClareCraigPath

Dr Clare Craig Profile picture
Aug 27
🚨USA - your babies are dying.

This is a professional deep dive into the official data.

It explains the alarming numbers of deaths of under 1 year olds.

It’s time the authorities took notice and they won’t unless you make them.

These babies did NOT need to die 🚨
The green dots show the annual mortality rate for babies under 1 year old in USA each year.

These are too high in the last three years ('21-'23).

People draw different baselines to claim these deaths can be ignored but I will show you why they cannot be. Image
Data from '24 and '25 are incomplete but we can take a closer look at when the deaths increased.

Here are deaths in US baby girls.

Nothing happens from March '20 to March '21. From April '21 the babies start dying.

There is a winter reprieve in '21-'22 then it returns. Image
Read 14 tweets
Dr Clare Craig Profile picture
Aug 26
USA - your babies are dying.

I have taken a deep dive to understand exactly what's happening with deaths of under 1 year olds.

Who wants to look at baby deaths?
I get it.
But DO NOT LOOK AWAY.
It is....
First of all I did this because of frustration with people arguing over what "expected" deaths should look like.

You can make up reasons for picking particular years and come up with a totally different story.

'99-'19 excess deaths from '21
'11-'16 deficit in deaths from '21 Image
What can we do to see if the rise is meaningful?

First we can look monthly ('24 and '25 data is incomplete)

Here are the monthly deaths for females which rises from March 2021 (having been below expected before) and stays high except for deficit in winter 2021-2022. Image
Read 13 tweets
Dr Clare Craig Profile picture
Jun 6
The overall excess mortality has reduced to almost zero but this hides too many deaths in the young.

Thread of excess mortality in England based on gov estimates of population and death rate trends from 2014-2019.

0-24 year olds. Image
25-49 year olds Image
Read 8 tweets
Dr Clare Craig Profile picture
Mar 20
One of the most important stories of lockdown has rarely been shared.

It is the story of Seattle.

They broke ranks and started an important experiment. 🧵
One research laboratory decided to break the rules for the sake of public health.

Rather than wait for a CDC approved covid test, they adapted an existing influenza test and started testing.

yahoo.com/news/seattle-l…
The regulator was not impressed.

This was a research laboratory doing clinical diagnostic testing and that was not allowed.

The lab was shut down on 9th March 2020.

nytimes.com/2020/03/10/us/…
Read 9 tweets
Dr Clare Craig Profile picture
Feb 9
Remember the Beta variant in South Africa?

Remember how AstraZeneca said their vaccine was only 10% effective against it?

They blamed the variant but it has nothing to do with that...🧵

bbc.co.uk/news/world-afr…
All the vaccines ever did was make people immune suppressed for two weeks.

The consequence was that those who were susceptible to a particular variant had their infections earlier than they would have.

You can measure after that point and get an illusion of benefit.
This trick only works if you vaccinate during a wave.

For the UK - we were fast getting to those most susceptible to dying. Our death wave looks like a witch's hat on top of Europe's because of the earlier infections.

N.B. the impact was felt by the unvaccinated too. Image
Read 6 tweets
Dr Clare Craig Profile picture
Jan 17
How do we how well the covid vaccines performed?

We can look at this question from multiple angles and see. 🧵
First, there was the "secondary attack rate".

When someone tested positive this measure could be taken of the percentage of household contacts that later tested positive.

If vaccines reduced risk of infection this should have fallen.

It did not. Image
Another measure is how many people developed antibodies before and after vaccine. Image
Read 15 tweets

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