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Dr Clare Craig Profile picture
@ClareCraigPath
Dec 9 • 25 tweets • 8 min read • Read on X
Scrolly
Today saw the release of minutes for the working group set up to advise MHRA on the covid vaccines.

They knew the issues but ignored them...🧵
On 27th November they briefly discussed a lack of any potential benefit for the under 50s but quickly concluded that there was a favourable risk/benefit for anyone aged over 16 years!

assets.publishing.service.gov.uk/media/67503fbc…Image
They made the case that the already infected should be injected because of lack of evidence of risk!

What about the fact they didn't need it! Image
They noted issues with early batches. Image
These were process 2 batches - not the bespoke process 1 batches given in the trial.

"it is not currently feasible to compare these two batches to those given to subjects in clinical studies." Image
"it may be the case that the batches the FDA are evaluating are further along the development lifecycle than those allocated for the UK"
The meeting ended with a reminder to put profits ahead of public health.

They reconvened the next day. Image
That evening they were told that they were to assess to worse batches.

For one they noted visible particulate matter in the vials.

They noted that another had degraded mRNA.
assets.publishing.service.gov.uk/media/67503fbc…Image
The batch with floaters in it was the infamous EJ0553.

This was used in the trial resulting in a 13 fold higher incidence of lymphadenopathy compared with trial doses. Image
These were "rejected vials" and they had not done a potency test. Image
Don't worry - the particles "disappear after the product is diluted"!

Also they "were not understood to be associated with a change in concentration of RNA containing LNPs" - but no measurement to confirm this! Image
It was a problem at the "end of the filling line" - i.e. it was from the dregs of the barrel. Image
Nucleic acids clump and lipid nanoparticles float - both could result in a higher concentration of product in the last batches to be filled.
The manufacturer admitted "no IPCs [in-process controls] or visual inspection is performed during the manufacturing process until after filling" Image
There was no data on the process 2 batch performance in humans and no stability data either - both were extrapolated from process 1 in the trial. Image
Barely any testing on stability. Image
And evidence that the RNA was degraded. Image
They ended with a request for more data on the particles. Image
Three days later Lord Bethel signed off on the drug.

A week after that injections began.
dailymail.co.uk/news/article-1…
They returned on 7th December - the day before injections began.

PHE were looking at serology (antibody levels in blood) in individuals that "have been vaccinated." Who are these people injected before 8th December? Image
They had not had the answers they requested on stability.

They detail all the issues then say - let's release the batches! Image
What on earth is redacted here? Image
The rest of the minutes that day were about AZ and Moderna.

No futher comment about the Pfizer batches that were going to be injected into people from the next day.
assets.publishing.service.gov.uk/media/6750518f…
Distribution was acknowledged as being all over the body. assets.publishing.service.gov.uk/media/6750518f…Image
The RNA was worse that the CT = clinical trial batches.

The batches in use had a "higher potency".

assets.publishing.service.gov.uk/media/6750518f…Image

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More from @ClareCraigPath

Dr Clare Craig Profile picture
Dec 4
I have been working on the MHRA funding model today.

It's awful.

There was no money to keep the public safe.

🧵
86% of MHRA funding comes from fees.

bmj.com/content/377/bm…

But MHRA do not set the fees.
MHRA cannot adapt the fees to the circumstances.
The fees are set by legislation.

legislation.gov.uk/uksi/2016/190/… Image
To take an extreme case, Herceptin was approved (by EMA) based on a trial of under 500 women.

If that happened today the fee would be £102,000 for MHRA licensing.

What would that cover?

gov.uk/government/pub…
Read 11 tweets
Dr Clare Craig Profile picture
Dec 1
There is a LOT in common between the lockdown policies and the assisted dying bill.

Let's start with them both centring on the fear of death and both leveraging emotional appeals to justify extreme measures.

But there's much more...🧵
Lockdowns crossed a Rubicon in terms of civil rights - overturning the social contract.

Euthanasia crosses a Rubicon in terms of moral norms - again overturning the social contract.

Support and opposition to both policies has come from across traditional party lines.
In both cases government did not provide a risk benefit analysis.

In both cases government has not had input from ethics advisors.
Read 14 tweets
Dr Clare Craig Profile picture
Nov 26
Here's a quick thread of Bad Covid Takes by the BBC.

Some are even from BBC Verify.

Let's start with mortality risk. For a man his age the meme was right (even with all the over diagnosed death).

BBC says 1%!
🧵 Image
Then we had the fear mongering about food shopping - before they admitted they were wrong.

"Use plastic bags only once." 🙄Image
To start: millions scared of using public transport

Then: No virus found in Feb 2021 Image
Read 14 tweets
Dr Clare Craig Profile picture
Nov 22
This has really upset some people.

This is not about blaming individuals.

It is just pointing out the timing of societal changes and how that has coinicided with the boomers journey through life.

Was it the boomers or was it all something darker?
🧵
The Baby Boomers are reaching the end of their lives.

But what kind of society have they left behind?

Their influence reshaped life, truth, and beauty—often with unintended consequences.
Boomers promised freedom and compassion: the right to choose, the power to define truth, and the liberation of beauty from tradition.

But they often created new problems when trying to solve old ones. Image
Read 15 tweets
Dr Clare Craig Profile picture
Nov 20
Is the cervical cancer problem a case of HPV vaccine failing or covid vaccine adverse events?

First, let's see how successful HPV vaccine has been in reducing cervical cancer. 🧵

dailysceptic.org/2024/11/19/the…
Cervical cancer is caused by HPV virus of which there are many types. HPV16 and HPV18 caused 80% of cancers. Others caused the remainder and could often cause the nastiest ones.

The vaccine was against 16 and 18.

Australia started first vaccinating 12-13 year olds from 2007.
The prevalence of HPV has reduced over time - but it reduced in the unvaccinated as well as the vaccinated.

HPV is sexually transmitted (but almost all women end up being exposed - it is pretty much ubiquitous unless you are a virgin).

pmc.ncbi.nlm.nih.gov/articles/PMC61…Image
Read 10 tweets
Dr Clare Craig Profile picture
Oct 8
Maternal deaths really kicked in once 2021 was included in the 2019-2021 period.

Too many mums dead since then.

The ethnic discrepancy "has decreased largely due to an increase in the maternal mortality rate amongst White women."

What are the white women doing since 2021?
🧵Image
The three year rolling period is confusing. 2018-2020 jumps because of lack of antenatal care in lockdown and covid.

The 2019-2021 jump is from vaccines.

Deaths from thrombosis have doubled compared to the preceding three year period.
Here is 2017-2019:

<1 per 100,000

npeu.ox.ac.uk/assets/downloa…Image
Read 10 tweets

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