SARS-CoV-2 variants are not simply competing with each other, but are in fact WORKING TOGETHER in a COOPERATIVE MANNER !!! π€ pmc.ncbi.nlm.nih.gov/articles/PMC10β¦
2) This study looked at how different versions of the COVID-19 virus, called variants, have evolved over time. The researchers found that these variants are not just competing with each other, but are actually working together.
3) As new variants emerge, they take in and use the genetic changes (mutations) from previous variants, rather than completely replacing them. This suggests the variants are building on each other's changes, not just trying to beat each other.
4) The study also showed that the combination of mutations in each variant helps balance out the extreme effects that individual mutations can have. This indicates the variants are working together to maintain a healthy balance, not just one variant dominating.
5) Another key finding was that the variants adapt to different seasons and locations in a coordinated way. The genetic signatures (haplotypes) of the variants became disconnected across regions due to seasonal changes.
6) This implies the variants are adjusting to environmental conditions together, not competing for a single environment.
Overall, the researchers conclude the variants exhibit "cooperative evolution." The accumulation of mutations creates a complex but balanced landscape ...
7) ...suggesting the variants are evolving together as a connected population, not just outcompeting each other.
In summary, the COVID-19 virus variants are not simply competing. They are working together by building on each other's changes, balancing extreme effects, and ...
8) ... adapting to different environments in a coordinated way. This cooperative evolution allows the virus to rapidly diversify and adapt as a united population.
Thanks for reading π and happy safe year 2025 π·
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IS SARS-CoV-2 BECOMING "INVISIBLE"? The Hidden Truth Behind the Pandemic
As the world strives to move past the COVID-19 pandemic, a troubling narrative has emerged: the perception that SARS-CoV-2 is becoming "invisible."
2) Governments and communities are eager to return to normalcy, leading to a tendency to downplay the virus's severity. Reports of new infections and long COVID cases have been totally minimized, creating a false sense of security ...
3) ...that the virus is no longer a significant threat. However, this perception is not only a matter of public sentiment. The virus itself has evolved, most notably with the emergence of the Omicron variant. Recent research reveals that Omicron exhibits a remarkable ability ...
2) This research shows that SARS-CoV-2, the virus that causes COVID-19, stops infected cells from dying. Normally, when cells die, it helps stop viruses from spreading. By keeping these cells alive longer, SARS-CoV-2 allows itself to multiply and also helps other viruses ...
3) ... like influenza A, grow more easily.
When someone has both SARS-CoV-2 and influenza A, the two viruses can make a person much sicker. The immune system gets overwhelmed, leading to more inflammation and damage to the lungs.
ENTROPY UNLEASHED:
How Viral Protein Interactions Drive Coronavirus Adaptation in Bats and Humans
Entropy, in a general sense, refers to the level of disorder or randomness in a system. biorxiv.org/content/10.110β¦
2) When we talk about protein interactions and viral behavior, entropy can be viewed as a measure of how complex and varied these interactions are.
In the context of the study about coronavirus interactions in bat and human cells, here's a simplified breakdown.
3) **Complex Interactions**: The study identifies how proteins from the coronavirus interact with host cells (both bats and humans). These interactions can be highly ordered (low entropy) or more chaotic (high entropy).
Patients care most about how COVID-19 affects their health and daily life, including for those with long COVID. Scientists focus on understanding the virus to find better treatments. Both views are important for dealing with the pandemic.
2) I'm bringing up this topic because, after talking so much about the disease, its long-term effects, treatments, and vaccines, many people have forgotten that we are dealing with the most dangerous virus humanity has ever faced.
Organelles provide the possibility for the virus to organize its RNA in PROTECTED structures, concentrate REPLICATION machinery ... nature.com/articles/s4146β¦
2) ...compartmentalize the replication process, and hide from immune detection.
Figure 1g - The large perinuclear clusters of viral RNA demonstrate how the viral RNA is organized into PROTECTED structures.
2) Figure 3d- The nanoscale puncta of the viral RNA-dependent RNA polymerase (nsp12) within and around the viral RNA clusters show the concentration of REPLICATION machinery.