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Jan 16 6 tweets 2 min read Read on X
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More from @drsthanus

Aug 26
A previously healthy, full-term, 2-month-old boy.

A 2-week history of these lesions.

Likely underlying cause of this baby’s findings? Image
Results of a complete blood count and comprehensive metabolic panel were normal.

Skin-biopsy sample obtained from the baby’s right forehead 👉 vacuolar interface dermatitis and perivascular and periadnexal lymphocytic infiltrates.
Anti-Ro and anti-La antibodies were positive in both the infant and the mother, the latter of whom was asymptomatic and had no history of autoimmune disease.

*Diagnosis...

Neonatal lupus erythematosus Image
Read 8 tweets
Jul 16
Young female patient with fever, cough and dyspnea.

Diagnosis? Image
Consolidation of the anterior segment of the RUL and the middle lobe of the right lung.

Moderate volume loss of the middle lobe. Image
Demonstration of Felson's silhouette sign.

On the PA view, the anterior segment consolidation is seen superior to the minor fissure of the right lung.
Read 5 tweets
Jul 11
A guide to interpreting an Electrocardiogram (ECG).

One... Image
Two... Image
Three... Image
Read 5 tweets
Jul 10
Findings?

Diagnosis? Image
Anti‐synthetase syndrome

Cutaneous features of antisynthetase syndrome

(a) demonstrates Mechanic's hands with Gottron's papules.

(b) highlights volar digit scaling or ‘Reverse Gottron's papules’.

(c, d) demonstrate ragged cuticles with Gottron's papules.
(e) highlights the lateral digit scaling seen in Mechanic's hands.

(f) Demonstrates subacute cutaneous lupus Image
Read 5 tweets
May 15
The image illustrates lymphocyte heterogeneity, focusing on T cell subsets and their roles in immunity and inflammation. Image
Key points include:

*Regulatory T cells (Tregs):

Maintain immune homeostasis and tolerance.

*CD4+ cells:

Differentiate into subtypes like Th1, Th2, Th17, Th9, and Th22, each with distinct functions.
*Innate lymphoid cells (ILCs):

Mirror T helper cell functions, contributing to immune responses.

*Memory T cells:

Provide long-term immunity and rapid response to re-infection.

*T cells in inflamed tissue:

Show heterogeneity in inflammatory bowel disease (IBD).

.
Read 5 tweets
Dec 25, 2024
Newborn...

Likely diagnosis? Image
A Rare But Pathognomonic Sign of Congenital Syphilis

Bullous palmoplantar rash.

The presence of an inflammatory bullous rash in the palms and soles, although rare, is a pathognomonic sign. Image
Ddx

Dystrophic bullous epidermolysis (EB)

Bullous impetigo

Bullous pemphigoid

Epidermolysis bullosa

●Congenital syphilis Image
Read 4 tweets

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