James Throt MBBS, MD, PhD, FRCPath Profile picture
Mar 1, 2025 6 tweets 3 min read Read on X
We are currently watching what I can only describe as the early stages of Frontotemporal Dementia on a mass scale playing out in real time.

The geopolitical ramifications of this are worrisome.

I am in no doubt about what I’m seeing.

The cause?

Ceaseless SARS-CoV-2 infections Image
Each new infection compounds the damage.

Damage to this area of the brain often causes ‘lack of insight’ (anosognosia ⬇️).

Self awareness is frequently impaired in FTD.

Tendency to act out of character often features.

Frontal lobe damage due to SARS-CoV-2 documented below ⬇️. Image
Image
FTD can cause increasing gullibility & worsening social cognition.

As previously stated, people with FTD usually don’t realise their symptoms/condition, i.e., blissfully unaware.

Appearing selfish or unsympathetic is common, as is loss of motivation & inappropriate behaviour. Image
Image
Am I stating that covid always causes the disease Frontotemporal Dementia? No.

But we know covid damages this specific area of the brain ⬇️, and so I would absolutely expect to see a mimicking of the signs/symptoms of FTD.

A resulting future rise in the disease itself is likely Image
Image
The frontal lobe is the largest part of the brain affected by ADHD, often maturing at a slower pace, showing disrupted activity & connectivity.

Hence I’d expect ADHD to worsen for those w/the disorder after infection/s.

I’d expect an increase in ADHD diagnoses (adult & child).
For the “covid is just a cold/nothing to worry about” lot, why do you care what I say?

What I say on X has absolutely zero bearing on how dangerous the virus is.

If what I’ve said is wrong, great! You’ll be fine won’t you. So who cares? I’m just some crazy dude online, right?

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More from @JamesThrot

Mar 8
Spreading a brain damaging virus on repeat for >6 years won’t be helping

And since nobody has an appetite for avoiding brain damage, there’s no end in sight

Pretending your 8th COVID infection is just another cold won’t protect you either

Actions & inactions have consequences
Frontal lobes refine behaviour. COVID damages them.

They regulate impulse control, empathy, moral reasoning & judgment.

Damaged lobes mean someone can remain articulate & knowledgeable while becoming reckless, cruel, suggestible & catastrophically bad at evaluating consequences
Executive function is also degraded.

Intelligence without executive function is dangerous. You can be sharp, knowledgeable, eloquent… and still impulsively destroy lives, misjudge catastrophes, or follow urges with zero moral compass.

The brain’s brakes & filters are gone.
Read 6 tweets
Mar 7
MAGA has gone full throttle at attempting to smear me and claim I am unequivocally incorrect in my suggestion Trump may have FTD

Exhibit A below ⬇️

These are not the words of a world leader with fully functioning frontal lobes

His internal filter is progressively diminishing Image
MAGA has been hanging off every word of a dementia patient. No matter how ridiculous or how unhinged it became. They followed. They regurgitated. They worshipped.

The baseline for what constitutes normal behaviour has continually shifted into increasingly preposterous territory.
Imagine having to reckon with the fact you were hoodwinked, beguiled & cajoled by a cognitively compromised senior citizen w/progressive brain atrophy. This won’t sit well.

Under normal circumstances this individual would be in a memory care facility.

But instead, they’re POTUS
Read 5 tweets
Mar 5
As a neurologist, I’ve dealt with Frontotemporal Dementia (FTD) patients for years

I often pondered how diabolical it would be if a world leader suffered the same fate

Now I’m seeing it play out in real time

Without impeachment, this will get darker than you could ever imagine
Frontotemporal dementia attacks the frontal lobes. The brain’s command center for judgment, empathy, impulse control, moral reasoning and long-term planning.

Imagine a world leader whose frontal lobes progressively fail, but no one intervenes.

Or worse, they cheer it on.
As FTD progresses, disinhibition dominates.

The leader may issue impulsive orders, make erratic public statements or flout norms & laws.

Even in those who were previously unmalicious, there would be a genuine neurological inability to foresee consequences.
Read 17 tweets
Mar 3
When you realise that frontal lobe dysfunction lowers resistance to manipulation & propaganda

And that aging leads to frontal decline, affecting how seniors vote

You’ll understand why the uncontrolled spread of a virus, well documented to damage the frontal lobes, is encouraged
Why?

Reduced prefrontal cortical function, whether from injury, aging or temp impairment, is associated with decreased critical evaluation, increased impulsivity & greater reliance on emotionally salient narratives, which can increase vulnerability to manipulation & propaganda.
A society’s resistance to propaganda depends on the cognitive health of its population.

If executive function declines at scale, you end up with worse decisions on an individual basis, and weaker collective judgment.

And SARS-CoV-2 is the virus that corrodes executive function.
Read 6 tweets
Feb 27
We are being gaslit into believing that the impulsivity, cruelty & polarisation we are seeing is purely cultural & political.

That explanation is psychologically comforting, but inaccurate.

It means we don't have to examine biology.

But we must.

COVID has entered the chat 🧵
The pretrontal cortex, particularly dorsolateral & orbitofrontal regions, is the regulatory governor of human behaviour.

It exerts top-down control over limbic threat circuitry.

It suppresses impulses before they become actions.

It filters speech before it leaves your mouth.
This is the system that allows you to

Pause.
Reconsider.
Anticipate consequences.
Inhibit bias.
Tolerate ambiguity.
De-escalate when provoked.

Remove or weaken that system and behaviour changes reliably.
Read 15 tweets
Feb 24
We need to have serious conversations about what COVID is doing to people’s brains, minds, behaviour & personalities.

But it is impossible to do so when people either refuse to acknowledge reality, or those who do acknowledge it tell us we can’t discuss it because it’s “ableist”
Throwing around accusations of ableism is a smokescreen. A way to avoid confronting how a mass-infecting, brain-damaging virus may be reshaping behaviour at scale.

Studies have found post-COVID changes in brain metabolism, grey matter, attention & emotional processing. FACT.
If a virus impairs the neural circuits responsible for empathy, inhibition & moral judgment, society as a whole becomes more susceptible to extremism, selfishness, cruelty & authoritarian propaganda.

This is scientifically & neurologically accurate.

Don’t like it? Tough shit.
Read 7 tweets

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