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James Throt MBBS, MD, PhD, FRCPath Profile picture
James Throt MBBS, MD, PhD, FRCPath
@JamesThrot
Consultant Neuropathologist, UK. Always backed by science. Using an alias.
11 subscribers
Apr 2 • 8 tweets • 2 min read
After targeted harassment & defamation, I’ve realised that people want to insist that doctors take all SARS-CoV-2 sequelae seriously, except for neurological sequelae/brain damage.

I’ve been called ableist & bigoted for stating that damage can negatively affect behaviour.

🧵 Suggesting that an increase in violent behaviour, diminishing empathy, increasing apathy & emotional lability, decreasing risk aversion & more disinhibition could be a result of damage to the frontal & temporal lobes in the brain is apparently ableist & bigoted.

Yet it is fact.
Mar 31 • 9 tweets • 3 min read
Lol.

Most people keep getting sick w/a few months respite between infections (Covid, flu, norovirus, take your pick).

What in gods name do people think Long Covid is?

“Yeah I get sick all the time since I had Covid & I’ve had that several times. But I don’t have long covid” 😂 My dude, that’s Long Covid.

“Erm no it’s not. I just keep getting sick”.

And what does it mean if you keep getting sick?

“Erm that my immune system isn’t working properly… [long thoughtful pause]”

Immune system damage sounds like Long Covid to me.

“You could be right”

I am
Mar 11 • 8 tweets • 3 min read
In neurology/psychiatry, we would call this Apathy.

Brain damage to the frontal lobe (dorsal anterior cingulate cortex) causes apathy & reduces empathy.

SARS-CoV-2 damages this region of the brain. Every. Single. Time.

More infections = more damage = more apathy.

🧵 Increase in apathy is often seen in traumatic brain injury, stroke & dementia.

It manifests as a lack of motivation/enthusiasm due to disruption in the brain regions responsible for goal directed behavior & reward processing.

Resulting in a lack of drive to engage in activities
Mar 10 • 4 tweets • 1 min read
“They create the idea of a terrifying plague that will kill us all, when the truth is far less frightening”

The truth is SARS-CoV-2 likely won’t kill you today, nor tomorrow.

But it will damage the brain, internal organs, blood vessels & immune system of everyone it infects. “Well covid did me no harm”

- You can lose up to 90% kidney function before experiencing any symptoms.

- Cancers often develop silently with symptoms only appearing at a more advanced stage.

- Blood clots develop silently.

- Brain damage often goes unnoticed by the sufferer.
Mar 8 • 12 tweets • 5 min read
Does anybody else feel that blaming a few months of lockdown for ill health in 2025, both physical & mental, is not only disingenuous & delusional, but a crusade to spread disinformation?

The public lap it up so they can reassure themselves the threat has vanished into thin air. We have outrageous hyperbole, as in the quoted tweet below, and almost everyone in the comments agree.

Peter is UK based, where lockdowns for the youngest children & those in year 6 lasted just 10 weeks, returning on 01/06/2020.

All other ages returned in September 2020. Image
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Mar 5 • 4 tweets • 2 min read
You’re a bit late to the party guys.

I’ve been telling you this for years.

I’m sick of talking about the frontal lobe and the damage SARS-CoV-2 is inflicting upon it.

Personality changes, executive dysfunction, emotional lability, cognitive decline.

Welcome to the new normal. As previously stated, personality changes will come before cognitive decline (intellect, memory, problem solving etc).

You don’t have to be a neurologist to see what’s happening to almost everyone around you.

SARS-CoV-2 almost always damages the brain of everyone it infects.
Mar 3 • 7 tweets • 5 min read
Have you developed symptoms of ADHD since 2020?

Or has your ADHD deteriorated since 2020?

The frontal lobe is the largest part of the brain affected by ADHD, often maturing at a slower pace with disrupted activity & connectivity.

Covid damages the frontal & temporal lobes.

🧵 I’m seeing far more people presenting with what they believe is ADHD, but I would suggest many of these cases are being misdiagnosed.

SARS-CoV-2 has been shown to reduce grey matter within the frontal/temporal lobes in the brain, and the damage goes far beyond simply being ADHD. Image
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Mar 1 • 6 tweets • 3 min read
We are currently watching what I can only describe as the early stages of Frontotemporal Dementia on a mass scale playing out in real time.

The geopolitical ramifications of this are worrisome.

I am in no doubt about what I’m seeing.

The cause?

Ceaseless SARS-CoV-2 infections Image Each new infection compounds the damage.

Damage to this area of the brain often causes ‘lack of insight’ (anosognosia ⬇️).

Self awareness is frequently impaired in FTD.

Tendency to act out of character often features.

Frontal lobe damage due to SARS-CoV-2 documented below ⬇️. Image
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Feb 28 • 5 tweets • 2 min read
Brief contact w/unmasked individual who tested + on LFT, whilst wearing an N95 myself.

I tested on LFT 2x per day for 3 weeks, all clearly negative.

No symptoms.

Antibody blood test 6 weeks later showed v high level of ABs. AB test 2 months prior - low levels.

I had Covid. To be clear, I am NEVER unmasked around ANYONE.

It is of course possible I caught it elsewhere, it’s simply that that was the only known positive contact.

The point here is that I had a completely symptom free infection whilst testing consistently negative on LFTs.
Feb 26 • 7 tweets • 3 min read
Pilots unable to follow the most basic of ATC instructions, which was to hold short of the runway.

So instead, they cross the active runway, where a 737 is landing.

The pilot also failed to check for incoming traffic on runway.

This is what covid brain damage might look like. I expand on this in the thread quoted below.

Note that the last line about having “no evidence” is quite clearly sarcasm.
Feb 19 • 9 tweets • 3 min read
Anecdotally, I’m seeing significant numbers complaining about health issues after SARS-CoV-2 infections, w/the majority NOT presenting with what people believe are traditional LC symptoms (fatigue, breathlessness, joint pain etc).

What % of LC cases are actually “traditional”?🧵 The majority assume LC only comes in the form of fatigue etc, which is demonstrably untrue. This is just one way in which the disease can present itself.

This causes many to believe the number of LC cases to be far lower than reality & even believe they don’t have it themselves.
Feb 18 • 6 tweets • 5 min read
Since Covid arrived:

“Why are so many children having developmental problems?

Why are there more car accidents & plane crashes?

Why are people more aggressive & less empathetic?

Why is everyone sick all the time?

Why is there more violence in schools?”

Gee, I dunno… Image
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Image “There isn’t more violence in schools and kids are fine”

Oh, ok 👍🏻. Image
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Feb 13 • 7 tweets • 3 min read
MUST WATCH:

This is what healthcare professionals really think about those of you suffering w/new health issues since SARS-CoV-2 arrived. It’s truly shocking.

I’m ashamed of my own profession.

This is intolerable.

Today, an NHS doctor on Sky News ⬇️

Guys, it’s just anxiety🧵 It gets worse.

This emergency consultant has the audacity to cite young people’s anxiety causing them to think that any form of chest pain/breathing problem is them having a heart attack.

Let’s not forget the fact that covid has been found to increase the risk of cardiac events
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Feb 7 • 14 tweets • 3 min read
Neurologist here.

Brain damage/injury can, and does, cause problems w/emotional regulation & lability.

It can diminish empathy, remove inhibitions, and cause significant alterations in personality.

It can make people say/do inappropriate things they otherwise wouldn’t have. This is nothing new, and it certainly isn’t ableist to discuss certain consequences of damage to the brain.

I’ve seen patients become drastically different people due to brain trauma/damage. Some can become aggressive, with some even committing crimes as a result.
Dec 31, 2024 • 5 tweets • 3 min read
No further comments necessary… Nothing to see here…
Nov 16, 2024 • 5 tweets • 2 min read
If you’re not noticing the (obvious) cognitive impairment in practically everyone around you, it may be due to your own cognitive decline.

Or denial is rearing its ugly head once again.

Perhaps it’s easier for me considering my background, but honestly, it’s so bloody palpable. How SARS-CoV-2 brain damage may present itself amongst your peers (& yourself)… ⬇️
Nov 7, 2024 • 12 tweets • 4 min read
I’m afraid this isn’t cut and dry at all 🧵.

First of all, damage/trauma to the brain can actually cause people to be more prone to sociopathic behaviour & even criminality.

The frontal lobe (FL) is responsible for the execution of empathy, hence diminishing empathy if damaged. Image
Image The FL is responsible for emotional regulation, incl anxiety/fear & hostility.

The ventromedial prefrontal cortex (vmPFC) is involved in decision making, moral competency/behaviour & evaluating risk.

Damage affects such functions & can make people more vulnerable to gullibility
Nov 2, 2024 • 5 tweets • 1 min read
Covid damages the frontal lobe of the brain.

Many areas of the frontal lobe are essential to the execution of empathy.

Most people are on their 3rd/4th+ infection/s already.

But it’s “empathy burnout”.

At least they’re recognising the loss of function I suppose. Many can’t. It’s also quite terrifying the masses of people attempting to justify the lack of empathy and actually double down on this.

People are convincing themselves that not only is this normal, but that they should be increasingly selfish & think less of the needs of those around them.
Oct 23, 2024 • 4 tweets • 1 min read
Can I reassert that with SARS-CoV-2 induced brain damage, it won’t be a lessening of intellect that you’ll be seeing first, but behavioural changes such as disinhibition, emotional lability, risk taking & impulsivity.

Frontal lobe damage impairs behavioural regulation. Whilst I’ve got your attention…

This thread goes into more detail regarding the damage inflicted upon the brain by SARS-CoV-2 (Covid), along with its most likely manifestations.
Jul 19, 2024 • 8 tweets • 2 min read
Studies re Long Covid insist on stating the % of people who succumb to this sequelae. I’ve seen incident rates from 3.5% up to 38% (after 3rd infection).

But what every single one of these studies fail to mention is that the reduction in grey matter occurs in 100% of individuals Would you not class brain damage (which looks permanent on the face of it) as Long Covid?

Permanent damage to any organ is LONG term. Hence ‘Long’ Covid.

So why is this always omitted from such reports into this condition?

What does the 3.5% etc include?
Jul 14, 2024 • 9 tweets • 3 min read
Why are so many w/Long Covid unaware?

Covid damages the frontal/temporal lobes within the cerebral cortex of the brain.

Damage to fronto-temporal parietal area causes Anosognosia.

Anosognosia means you simply cannot recognise your own health conditions & disease.

Facts ⬇️✅

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Image Oh, did I not mention that every single covid infection causes damage to this area of the brain, regardless of severity of symptoms (including asymptomatic)?

Those of you on multiple infections? Perhaps try to keep that number as low as possible.

More infections = more damage.