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James Throt MBBS, MD, PhD, FRCPath Profile picture
James Throt MBBS, MD, PhD, FRCPath
@JamesThrot
Consultant Neuropathologist, UK. I dissect brains for a living. Always backed by science. Using an alias.
Mar 18 • 11 tweets • 2 min read
Because COVID has caused so many health problems for so many people, they’re inundated with patients demanding help for their new ailments.

And because nobody, including doctors, wants to acknowledge COVID, it’s more convenient to label the myriad of health problems as “anxiety” “My new issue that just so happened to appear post-2020 is nothing to do with COVID”

Maybe not.

But repeated infections w/a virus that is vasculotropic, neurotropic, cardiotropic, thromboembolic, oncogenic & damages the immune system certainly won’t be beneficial to your health
Mar 15 • 7 tweets • 2 min read
Two students at the University of Kent in the UK have died following an outbreak of "invasive" meningitis.

A further 11 students are currently in hospital and reported to be seriously ill.

All normal on plague island during a never-ending SARS-CoV-2 pandemic. Image
Image It’s worth knowing that COVID has been associated with T-cell exhaustion, lymphopenia, impaired interferon responses & persistent immune dysregulation.

When host immune regulation is altered, susceptibility/vulnerability to other infections, like meningitis, can increase.
Mar 8 • 6 tweets • 2 min read
Spreading a brain damaging virus on repeat for >6 years won’t be helping

And since nobody has an appetite for avoiding brain damage, there’s no end in sight

Pretending your 8th COVID infection is just another cold won’t protect you either

Actions & inactions have consequences Frontal lobes refine behaviour. COVID damages them.

They regulate impulse control, empathy, moral reasoning & judgment.

Damaged lobes mean someone can remain articulate & knowledgeable while becoming reckless, cruel, suggestible & catastrophically bad at evaluating consequences
Mar 7 • 5 tweets • 2 min read
MAGA has gone full throttle at attempting to smear me and claim I am unequivocally incorrect in my suggestion Trump may have FTD

Exhibit A below ⬇️

These are not the words of a world leader with fully functioning frontal lobes

His internal filter is progressively diminishing Image MAGA has been hanging off every word of a dementia patient. No matter how ridiculous or how unhinged it became. They followed. They regurgitated. They worshipped.

The baseline for what constitutes normal behaviour has continually shifted into increasingly preposterous territory.
Mar 5 • 17 tweets • 3 min read
As a neurologist, I’ve dealt with Frontotemporal Dementia (FTD) patients for years

I often pondered how diabolical it would be if a world leader suffered the same fate

Now I’m seeing it play out in real time

Without impeachment, this will get darker than you could ever imagine Frontotemporal dementia attacks the frontal lobes. The brain’s command center for judgment, empathy, impulse control, moral reasoning and long-term planning.

Imagine a world leader whose frontal lobes progressively fail, but no one intervenes.

Or worse, they cheer it on.
Mar 3 • 6 tweets • 2 min read
When you realise that frontal lobe dysfunction lowers resistance to manipulation & propaganda

And that aging leads to frontal decline, affecting how seniors vote

You’ll understand why the uncontrolled spread of a virus, well documented to damage the frontal lobes, is encouraged Why?

Reduced prefrontal cortical function, whether from injury, aging or temp impairment, is associated with decreased critical evaluation, increased impulsivity & greater reliance on emotionally salient narratives, which can increase vulnerability to manipulation & propaganda.
Feb 27 • 15 tweets • 3 min read
We are being gaslit into believing that the impulsivity, cruelty & polarisation we are seeing is purely cultural & political.

That explanation is psychologically comforting, but inaccurate.

It means we don't have to examine biology.

But we must.

COVID has entered the chat 🧵 The pretrontal cortex, particularly dorsolateral & orbitofrontal regions, is the regulatory governor of human behaviour.

It exerts top-down control over limbic threat circuitry.

It suppresses impulses before they become actions.

It filters speech before it leaves your mouth.
Feb 24 • 7 tweets • 2 min read
We need to have serious conversations about what COVID is doing to people’s brains, minds, behaviour & personalities.

But it is impossible to do so when people either refuse to acknowledge reality, or those who do acknowledge it tell us we can’t discuss it because it’s “ableist” Throwing around accusations of ableism is a smokescreen. A way to avoid confronting how a mass-infecting, brain-damaging virus may be reshaping behaviour at scale.

Studies have found post-COVID changes in brain metabolism, grey matter, attention & emotional processing. FACT.
Feb 22 • 4 tweets • 1 min read
People don’t “pretend” everything is fine.

They adapt to dysfunction. This becomes the new “normal”.

The human mind will tolerate astonishing levels of decline if it happens slowly & collectively.

There is not going to be a “reckoning”. Just a slow, gradual, painful collapse. The most effective way to normalise decline is to make sure everyone declines together.

Collective deterioration is socially self-sealing. If everyone’s diminished, no one feels uniquely diminished.

You’d only notice if observing from outside.

i.e. the ones avoiding infection.
Feb 16 • 9 tweets • 2 min read
If you found out a music concert was going to secretly release a noxious gas to subtly harm the attendees, would you just don a gas mask & attend anyway? You’d be safe. They wouldn’t.

Would this impact your enjoyment? Or would you feel uneasy being surrounded by potential harm? Attending a crowded indoor event masked is like joining an event secretly exposing everyone else to a mild toxin.

You may be safe, but you’re legitimising harm.

These events spike community infections, making hospitals, children, and vulnerable people more at risk.
Jan 8 • 17 tweets • 3 min read
Has police & military behaviour become harsher, more rigid & more escalation-prone since 2020?

This isn’t just about politics or “bad apples”.

There’s a deeper, biological factor being ignored…

SARS-CoV-2

I’m a neurologist, and I’ll explain what’s going on here 🧵. It’s common knowledge that both policing and the military already over select for people with certain traits:

- high threat sensitivity
- comfort with hierarchy
- rule based cognition
- obedience over ambiguity
- identity anchored in authority

This was true long before COVID.
Dec 9, 2025 • 6 tweets • 2 min read
You don’t have to be a neurologist to see patterns.

Everyone I know who avoids mitigation looks noticeably different from their pre-covid selves. In temperament, in consistency, in emotional regulation, in decision making.

The changes are everywhere. People just normalised them A key problem we have is that neurological changes often impair the very systems needed to notice those changes.

It’s an anosognosia-like loop.

The more dysregulated someone becomes, the more convinced they are that nothing is wrong.
Dec 6, 2025 • 7 tweets • 2 min read
And COVID is making an ever increasing proportion of people fall into that weak/vulnerable category that capitalism is happy to throw to the wolves.

Eventually, EVERYONE who is doing nothing to prevent repeat SARS-CoV-2 infections will be weak/vulnerable. This is what COVID does People think vulnerability is a fixed trait. It isn’t.

With SARS-CoV-2, it’s a moving target.

And repeat infections keep moving it toward them.

Cumulative damage always catches up.

Keep letting a brain-damaging virus rip and the ‘vulnerable’ category expands year after year.
Nov 26, 2025 • 17 tweets • 3 min read
If you still believe COVID left the population “unchanged”, open a dating app. It sounds absurd, but stay with me here.

The cognitive bluntness is so widespread that the dating platforms themselves have had to acknowledge behavioural deterioration since 2020.

It’s not subtle🧵 Since 2020, apps report the same pattern: shorter messages, less reciprocity, fewer follow-ups, lower meet-up rates & a collapse in sustained conversational ability.

This isn’t just “people being tired”. It’s a measurable degradation of attention, initiative & social cognition.
Nov 24, 2025 • 6 tweets • 2 min read
Oh they know.

The reason any utter of the word “COVID” is met with awkward silence, abrupt subject changes, or mockery is no coincidence.

That’s what denial looks like when the stakes are too high for people to admit what they already sense.

You’re letting them off too easily. Universal internet access & AI at everyone’s fingertips in year 6/7 of COVID. Yet we’re still pretending the public is merely “uninformed”?

This isn’t a knowledge gap, it’s deliberate avoidance, a psychological defence to shield people from the consequences of their own choices.
Nov 16, 2025 • 6 tweets • 1 min read
There’s a pervasive misunderstanding in conversations about COVID’s neurological impact.

Many people assume that saying “frontal lobe damage reduces empathy” means everyone who’s had COVID instantly becomes amoral & unethical.

That’s reductionism at its finest. 🧵 Frontal lobe impairment is not an on/off switch.

Someone with naturally high empathy can still appear extremely empathetic, even if their capacity has measurably declined.

It’s a shift, not a reset.
Nov 15, 2025 • 12 tweets • 2 min read
Let’s talk about one of the most dangerous and under-discussed consequences of SARS-CoV-2: neurological damage. More specifically, frontal lobe dysfunction.

This is being deliberately downplayed, in part due to a misguided weaponisation of “ableism” discourse. That’s a problem🧵 Here’s the truth.

SARS-CoV-2 is a neurotropic virus. It can invade the central nervous system, either directly or through inflammatory damage.

It’s been detected in brain tissue, and it can cause lasting neurological impairment.

This is not speculative.
Nov 11, 2025 • 14 tweets • 3 min read
Calling it “ableist” to discuss SARS-CoV-2 related frontal lobe dysfunction misunderstands both neurology & ethics

Frontal lobe injury can cause apathy/disinhibition/moral blindness & aggression since these are the functions the region governs

This is neurobiology, not stigma🧵 Autism/ADHD/PTSD etc are forms of innate neurodiversity. Stable, lifelong neurotypes

Frontal lobe injury from COVID is acquired neurodegeneration. A progressive erosion of neural circuits governing empathy, foresight, inhibition & moral reasoning

Conflating the two erases both.
Nov 10, 2025 • 9 tweets • 2 min read
Cognitive decline from repeated SARS-CoV-2 infections & the rise of AI tools like ChatGPT = a perfect storm.

Here’s why this could reshape society in ways most people aren’t ready for 🧵 Repeat infection = cumulative damage to the brain. Particularly the frontal lobe, which governs empathy, foresight, impulse control & reality testing.

That’s the part of the brain that lets you question, reflect & doubt. Without it, a person becomes gullible, rigid & manipulable
Nov 7, 2025 • 7 tweets • 2 min read
We have not yet seen the worst of the neurological effects of Covid.

End. What’s coming:

- Frontal lobe degeneration
- Personality & empathy decline
- Early-onset dementia
- Parkinson’s
- Alzheimer’s
- Motor neurone disease
- Chronic fatigue & dysautonomia

All accelerated by reinfection.

Reinfections that are happening 1-2x annually.
Oct 28, 2025 • 17 tweets • 4 min read
Why are Religion & Fascism rising? Two faces of the same psychological/neural process.

They’re far more intertwined, and dangerous, than you might have ever believed.

SARS-CoV-2-induced frontal lobe (brain) damage makes both more likely.

A neurologist’s explanation 🧵

1/17 Image
Image Religion and authoritarianism share the same psychological architecture: submission to authority, suppression of doubt, and moral outsourcing.

Both dissolve individual responsibility and reward conformity over critical thought.

And both are on the rise, simultaneously.

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