How did we get creativity? Neanderthals migrated North got to 51st latitude froze started wearing animal skins and used fire inside caves and their brains shrunk as a result. As they shrunk due to dehydrated melanin sheets, melanin becomes dopamine. The dopamine built up and we got art culture and DaVinci.Image
2. Note how melanin degrades on the slide on the top line. It degrades into dopamine, other amines, and L-DOPA. When you undergo a TBI, as the Neanderthals did by going too far up on the planet, it gets cold, and you need animal skins and fire to keep you warm. Why? Neanderthals did not have uncoupled haplotypes yet. That is a human innovation to high-latitude living. As a result, they flood their shrinking brain with more dopamine than they should have had. Voila = You eventually get Michealangelo, DaVinci, and Rembrandt.Image
3. Look at the picture. Image
4. Image
5. Paying attention? Image
6. The Great Oxidation Event or Oxygen Holocaust is going on in every skull on Earth now due to nnEMF and blue ubiquitous use.

If you understand what I have laid out on my blogs over 20 years, all chronic diseases are photo-bioelectrical electrocution of the inside of a cell. Why? Dehydrated melanin causes massive amplification of the DC electric current a cell makes. When you dehydrate cells of water, it also increases the amount of NaCl left behind, which increases the chance of stray electrical current spreading where it should not be.Image
7. Remember what Nick Lane told us in his book, Power, Sex, and Suicide. A healthy inner mitochondrial membrane contains 30 million volts of electric charge. This charge would typically be devastating to a cell. It raised a big question when I read this fact long ago. How does a cell dampen the electrical charge? @MitoPsychoBio

Pure water containing no ions is an excellent insulator of electric charge. This is why Nature created the DDW, which was made by mtDNA at cytochrome C oxidase. What was the stimulus for her to gain this wisdom?

It was the wound of the Great Oxidation event. The toxic wound Nature sustained from the presence of oxygen and massive electrocution drove endosymbiotic growth or the merger of the two domains of life on Earth 650 million years ago. Nature would never have innovated mitochondria without photo-bioelectrocution as the wound. It was the stimulus that created eukaryotes.Image
8. What ruins this system? Ruin the water and increase stray electrical currents, and you get cancer.

FYI, when you add SV40 and LNPs together, in our modern world, it is the perfect soup for creating a turbo cancer.

Wake the fuck people.

MAHA = HAHA. Image
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More from @DrJackKruse

Jul 18
Why do I say Reta will subtract longevity from humans and disagree with Morse?

1. The Nocturnal vs. Diurnal Disconnect

The Baseline: Rodents (nocturnal) and humans (diurnal) have completely inverted circadian clocks governing metabolism, nutrient intake, and cellular repair.Stem Cell Vulnerability: Human stem cell niches rely on strict circadian gating to time replication and DNA repair.

The Problem: If a drug blunts or alters a pathway that protects stem cells from exhaustion, humans are exposed during their active/inactive phases differently than rodents.

The Consequence: Forcing a diurnal system into a non-gated metabolic state could accelerate stem cell depletion or dysfunction significantly faster than seen in nocturnal animal models.

2. Replacing Native Pulses with Constant Signals

Natural States: Endogenous GLP-1, GIP, and glucagon are highly pulsatile. They spike rapidly in response to nutrients and drop just as quickly.

The Retatrutide Shift: Retatrutide provides 24/7, high-affinity, continuous activation of all three receptors.

Systemic Downregulation: Biology relies on pauses to reset receptor sensitivity. Constant, unyielding agonism eliminates the natural "resting" state of these pathways.

3. The Danger of "Non-Identical" Signals

Altered Biasing: Retatrutide is not a perfect replica of native hormones; it is engineered with specific structural modifications to extend half-life and alter receptor affinity balances.

Downstream Repercussions: By binding non-identically and permanently, it can trigger alternative intracellular signaling cascades (biased agonism) that bypass the body's natural negative feedback loops.

The Ultimate Risk: Without circadian gating or pulsatile resets, the system faces chronic metabolic stress, potentially leading to accelerated cellular aging, organ-specific stem cell burnout, or irreversible receptor desensitization once the drug is withdrawn.

Then there is the Blau study that showed stem cells are DESTROYED by these drugs.

My first-principles bridge is entirely consistent with the biological trajectory: human muscle stem cells face a significantly higher risk of accelerated exhaustion under these conditions than nocturnal rodent models.

The newly published data from the Stanford University Blau Lab demonstrates a direct, drug-specific impairment of muscle stem cells (MuSCs) caused by semaglutide. When you layer my previous point regarding circadian gating, constant signaling, and human diurnal physiology onto this new mechanism, the risk profile amplifies dramatically in humans. So Dr. Morse is wrong because he never took any of these things into account. His patients should be aware he sells half truths to them before trusting his centralized Rockefeller medicine inspired advice.Image
2. The First-Principles Compounding Effect

Applying my deductive framework to this specific 15-PGDH / PGE2 pathway reveals why human outcomes could be considerably worse: Why?

The Rodent Reality: Mice have a vastly higher baseline metabolic rate and an incredibly robust, rapid tissue-regeneration capacity compared to humans.

The Circadian Buffer: Because mice are active at night, their natural cyclical spikes in muscle repair and stem cell activation match their evolutionary clock. Even when blunted by a drug, their hyper-efficient baseline repair mechanisms shield them from total regenerative collapse under steady-state conditions.

The Human Penalty: Humans lack this rapid baseline turnover. If human MuSCs are forced into a state of continuous, non-circadian-gated suppression by a 24/7 long-acting agonist, the body cannot easily compensate. The result is a much faster slide into irreversible stem cell senescence and lose longevity.Image
3. Chronic Suppression vs. The 15-PGDH Gerozyme

The Mechanism: The data shows that semaglutide compromises MuSC function, resulting in a failed regenerative response after injury (dropping to a staggering 8% efficiency in mice).

The Aging Acceleration: In humans, the enzyme 15-PGDH (the "gerozyme") naturally rises with age, progressively degrading the PGE2 repair signal and wasting muscle.

The Compounding Crisis: If a long-acting incretin drug inherently suppresses stem cell function, it acts as a chemical accelerator of the aging process. In an adult human who already has elevated gerozyme levels, adding a drug that independently cripples stem cell mechanics creates a dual-pronged assault on muscle architecture. This is why Reta will destroy longevity in users.
Read 10 tweets
Jul 17
1. Maybe your doctors do not know because they are centralized Rockefeller trained on a biochemistry diet devoid of biophysics, Chris.

The decentralized MDs I treat know why these happen.

These five reasons integrate seamlessly into my quantum biophysical framework, exposing serum ferritin as a diagnostic facade that hides the true driver of cellular degeneration: the loss of magnetic pinning and the systemic release of unsequestered free iron.
2. Serum Ferritin as an Empty "Ghost Antenna"

The Central Dogma Blindspot: Traditional medicine measures serum ferritin under the assumption that it mirrors total tissue iron stores. Yet, ferritin experts acknowledge that serum ferritin contains almost no iron core and its origin remains unknown.

The Quantum Reality: Ferritin is only a safe shield when it exists inside the cell as a fully intact, structured nanocage enclosing a superparamagnetic ferrihydrite core.

Serum ferritin is a "Ghost Antenna", a cellular debris marker. When a cell experiences a dielectric collapse due to a failing dynamo, non-native EMF (nnEMF) or isolated blue light, its internal water table drops from K=160 down to bulk water K=78. This loss of capacitance triggers Landauer liquidations, causing the cell to dump its broken, empty protein shells into the serum as a desperate coping mechanism. Measuring this empty shell tells you nothing about the quantum state of the iron core itself.Image
3. The Statistical Smear of the Normal Range

The Central Dogma Blindspot: A "normal" ferritin reading is treated as definitive proof of healthy iron homeostasis.

The Quantum Reality: This is literal biochemical aliasing. A normal serum reading completely obscures high-frequency micro-environmental chaos. It cannot tell you if the iron inside your tissues is safely locked within a homochiral protein fold or if it is currently acting as a un-shielded, dirty antenna.

If the local magnetic pinning from the planetary geodynamo is weak, even a normal amount of iron will slip through the Intersystem Crossing (ISC) gates, converting triplet oxygen into destructive diamagnetic singlet oxygen. Rockefeller biochemists never learn about the two states of oxygen what controls their flip in mitochondria. Decentralized medicine teaches CISS and ISC operation for electron spins.Image
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Read 7 tweets
Jul 13
1. QUESTION ON MY FORUM: Hello to everybody. I am 56 and into permaculture, I learned about decentralised medicine from Dr. Jack Kruse about 1.5 years ago since than I am following him and created an account on the forum a few month back I also subscribed to the Patreon blog and I am considering myself a noob and I have sill so much to learn. I am applying the things as I am learning in my own life and among my family members as they are willing to listen and to learn. My mother had a brain tumour decades ago which led to the removal of her hypophisis and a long list of medications and side effects in all the years. We are living in Spain at the Costa del Sol / Andalucia close to Malaga. I would describe it as slow, steady transformation of our lives. I am thankful to Dr. Jack Kruse and all the people involved in the decentralised medicine movement empowering the people.

But this post is not about myself, my friends son 26-year-old was diagnosed after multiple seizures in the middle of May.

I'm looking for thoughts from anyone with experience of low-grade gliomas, particularly in the insular/temporal region.

So far:

MRI suggests an infiltrating left temporo-insular glioma.

Initially measured 45 × 55 × 40 mm ( mid May)

Latest MRI measures approximately 50 × 55 × 55 mm (about 6 weeks later)
The tumour does not enhance with contrast.
Functional MRI and tractography show it lies very close to the language network (Broca's, Wernicke's and the left arcuate fasciculus).
He has no neurological deficits apart from the seizures, which are now controlled with levetiracetam.
The neurosurgical team is considering awake surgery and has completed language mapping in both English and Spanish.
They are still waiting for surgery (scheduled for September, no exact date yet), so they do not yet have a biopsy or molecular diagnosis.
2. ANSWER: If the kid does not learn how to "magentically pin" his proteons and electrons = singlet oxygen = glioma.

CITES
youtube.com/watch?v=W7cHkG…

Low ultraviolet B and increased risk of brain cancer: an ecological study of 175 countries
pubmed.ncbi.nlm.nih.gov/20948235/
3. DISCUSSION: My work connects Otto Warburg’s vintage bioenergetic principles to modern quantum mechanics and the dark history of institutional science.
By detailing how a drop in cellular voltage opens the door to functional hypoxia, matrix deuteration, and the collapse of the mitochondrial F₀F₁-spin motor, I have laid bare the exact biophysical mechanism behind cancer and metabolic disease.

The 1910 Flexner Report was the tool used to deliberately steer Western medicine away from cellular biophysics and electrophysiology. It was a biological Landauer attack.

By standardizing medical education around a petrochemical-pharmaceutical model, it reduced the complex, spin-polarized human matrix into a simple chemistry set to be treated with synthetic, patentable pills.

Here is the strict decentralized first-principles breakdown of the structural model that Warburg started, and that modern quantum biology completes.Image
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Read 14 tweets
Jul 4
Ketogeneic diet provides more H+ and less D+. For GBM this is a benefit but DDW use works way better. Why? Because water provides the matrix more H+ to offset the UCP-2 deuterated gate.

Isotopic fractionation is only part of the story of cancers like GBM. I know I have treated hundreds of them over 40 years.

What has centralized science missed? THE KEY PART.

For the first 2 billion years of life, the Earth's magnetic dipole field was weak, fluctuating, and unorganized. Because the planetary magnetic field lacked the strength to stabilize spin states across large scales:

High Quantum Friction: Lacking a strong magnetic field to stabilize spin orientation, early anaerobic organisms could not efficiently utilize Chirality-Induced Spin Selectivity (CISS). Electrons scattered wildly, generating massive amount of thermodynamic waste heat and raw free radicals. Without a dynamo, oxygen stays in the singlet state. It never gets into the triplet state. In complex tissues like the BRAIN, this is the key to cancer in the brain.

Chemical Constraints: Without organized spin-pinning, life was forced to operate at a slow, low-energy metabolic pace. The human brain cannot tolerate this. As a result of a weak dynamo, the brain gets stuck in the "biochemical mud" of singlet state oxygen (Warburg shifted) relying on primitive fermentation, local chemical gradients, and simple, flat molecular structures. Complexity was strictly capped by the high thermodynamic cost of electron scattering due to inability to polarize electron spin to build coherence.

The Neoproterozoic "Stall": During the weak-field era prior to the Cambrian, there was no "Magnetic Pin" to distinguish between mirror-image molecules. This is why there was no complex brain evolution as yet. Electron spin was chaotic and could not be organized to the triplet state. Life stayed in a low-energy, Singlet-trapped state because it couldn't "rectify" the signal. Nick Lane, Seyfired, and you still do not realize this basic fact, but I have for 25 years. DIET CANNOT FIX A GBM.Image
2. Why are all GLIOMAS linked to low Vitamin D status. No centralized MD or PhD has a clue why this happens.

I teach decentralized Medicine to these people PRECISELY why it happens. Image
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3. WHY IS LOW VITAMIN D ALWAYS ASSOCIATED WITH GBM? Without the sun you have no melanin in which to drive CISS quantum biology to feed H+ and triplet state oxygen into your brain's mito matrix. This leads to the cancer.

What don't functional allopathic clinicians see that decentralized ones do? They do not understand the spin state of the photon and how chirality fits in this story. Why taking Vitamin D supplementation does not equal skin in the game. You didn’t just pop a vitamin D pill. You tried to hijack a cosmic symphony, a blazing, stellar-forged photonic command chain that ignites when UVB photons, spun with the raw angular momentum of a whirling star, slam into your skin’s crystalline water grid.

This isn’t a nutrient; it’s a celestial spark, a quantum handshake between a star and your cells, locked in perfect frequency, angle, and orbital rhythm. These photons don’t deliver a substance; they unleash energy and code. They surge through your dermal layers, flipping magnetic fields, ripping open voltage pathways, and rewiring redox gradients. Your mitochondria?

They’re not just powerhouses; they’re torsion-driven quantum processors that order the spin of electrons from food before they enter the ECT.

Electrons have to be humming with the PROPER SPIN to the beat of Faraday’s Law:∮ E·dl = −dΦᵦ/dt. This is a law no one in centralized biology ever learns.

A shifting magnetic flux drives electric currents through a closed loop, and your body is that loop: BRAIN, skin, water, charge, geometry. When the photon hits, cholesterol twists, membranes polarize, electron clouds morph into structured torrents. Enzymes like CYP2R1 and CYP27B1 don’t sense molecules; they feel tension.

The VDR doesn’t care about presence; it craves resonance and that resonance require electron spin to be parallel.

Only when your nuclear matrix syncs with the incoming solar wavefront does the genome throw open its gates, transcribing over 900 genes in lockstep with this stellar pulse carrying spin data.

But that capsule you swallowed? It’s a hollow echo, a molecule stripped of its cosmic fire and the spins are chaotic. No flux, no curvature, no induction, just a shadow without a sun. Your chemistry churns, but the quantum corridor stays dark. The waveform never crashes.

The chromatin twists, but it’s out of tune, like a satellite drifting without its planet, not broken but grieving. The star’s signal burns on, but your receptors are out of phase. Their circadian phase is not locked, and your genome and immune system become unprotected. The contract was electromagnetic, and coherence doesn’t negotiate. Break the symmetry, as Noether warned, and something, some spark of cosmic alignment, is lost forever. Step into the light, or stay in the shadow. The universe doesn’t wait for anyone to get things right. The lesson is all in the slide. No functional, allopathic, or centralzied MD knows this and this is why they keep ordering labs on you, telling you a ketogenic diet is a panacea when it is not in GBM.Image
Read 5 tweets
Jul 1
Overcoming the Environment: Sun, Blue Light, and "Grounding" Your lifestyle profile tells the story. You avoiding the sun, being very pale, living in a city environment dominated by artificial blue light, and lacking contact with the earth, adds major environmental friction to an already compromised immune system.

The Sunlight & Acid Connection: Avoiding the sun causes deep Vitamin D receptor starvation. Vitamin D is a primary epigenetic regulator of T-regulatory (Treg) cells, the "brakes" of the immune system. When Vitamin D is chronically low, Treg cells fail, allowing the auto-reactive CD4+ T-cells to aggressively attack your stomach lining unchecked. Furthermore, sunlight exposure triggers local proopiomelanocortin (POMC) cleavage, which aids in autonomic nervous system balance, is essential for the vagus nerve to stimulate stomach acid production.

The Blue Light & Circadian Inversion: Living in an artificial blue-light environment under the constant glare of screens destroys your evening melatonin production. Melatonin is a potent mitochondrial antioxidant. The stomach lining has a incredibly high density of melatonin receptors because it relies on overnight sleep cycles to repair the mucosal lining from daytime acid exposure. High blue light at night prevents this repair cycle, leaving an already inflamed stomach vulnerable to faster atrophy.

The "Grounding" and Tech Physics: From a biophysical perspective, constant exposure to electromagnetic frequencies (EMFs) from city technology without physical contact with the earth alters cellular voltage-gated calcium channels (VGCCs). When VGCCs are chronically excited by ambient fields, it drives intracellular oxidative stress, fueling the fires of systemic inflammation.

I hope your audience learns a lesson. Do not listen to your advice. You're diagnosis puts you closer to death than longevity and it is entirely tied to your choices and beliefs.Image
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2. How would the MITF-AMPAR pathway feed into this situatioon since you've slef blocked the sun to get this autoimmune condistion?

If we theoretically block the sun (removing ultraviolet radiation/UVR), the impact on the MITF-AMPAR pathway interacts with the risks of autoimmune gastritis (AAG) through two primary mechanisms: systemic autoimmune cross-reactivity and altered oncogenic potential.

In the context of cellular signaling, AMPAR (ionotropic AMPA glutamate receptors) and MITF (microphthalmia-associated transcription factor) form a crucial regulatory loop. Normally, keratinocytes release glutamate, activating AMPAR on neural-crest-derived cells. This activation upregulates MITF to manage cellular survival, differentiation, and structural integrity.Simulating a scenario without sunlight alters this biological feedback loop and influences the risk profile of gastritis in several distinct ways:

1. Accelerated Melanocyte Detachment and Vitiligo Co-occurrence
The Pathway Breakdown: Sunlight (UVR) typically triggers the systemic production of alpha-MSH, stimulating MITF expression. Concurrently, glutamate signaling via AMPAR sustains MITF to preserve the physical structure and adherence of melanocytes. Blocking the sun downregulates this pathway, leading to a loss of cellular actin microfilaments and causing cells to "round up" and detach.

The Gastritis Connection: Landmark comparative pathologies published on Authorea show that Vitiligo (melanocyte destruction) and Autoimmune Gastritis (parietal cell destruction) share an identical initiating mechanism: cellular detachment driven by adhesion loss.

In a sunless environment, a collapsed MITF-AMPAR loop triggers widespread melanocyte instability. This cellular debris presents highly concentrated target antigens to CD4+ and CD8+ T-cells, priming systemic auto-reactivity. This heightened immune state can cross-activate T-cells against the gastric mucosa, driving or worsening AAG.
3. Phenotype Switching and Aggressive Gastric Cancer Progression

The Pathway Breakdown: MITF functions as a cellular "rheostat". High MITF expression promotes normal differentiation and localized proliferation. Low MITF expression drives a "phenotype switch," shifting cells into a highly invasive, migratory, and stem-like state.

The Gastritis Connection: As detailed in the earlier discussion on AAG risks, chronic gastritis frequently progresses down the Correa cascade into Gastric Cancer (GC). If the sun is blocked, the withdrawal of UV-induced signaling combined with an inactivated AMPAR loop sharply downregulates MITF. In patients where gastritis has already triggered early-stage neoplastic cells, this low-MITF state acts as a genetic green light for metastasis. It accelerates the transition from standard metaplasia to aggressive, invasive gastric adenocarcinoma.
Read 5 tweets
Jun 23
I told @mattkratter that I thought BIP-110 did not go far enough. I think the real sin by Core was Segwit. But the Fabian plan is always to use small changes so no sees the real attack. It's activation was highly sketchy and smells of Fabiansm thought at MIT where the math & physics guys thought of this in Thiel's secret meetings with Epstein. If we added an inversion to Segwit discount, meaning make it cheaper to put non monetary gains data in Op Returns it would make the attacker have to bear a steep opportunity cost to pollute the UTXO set. I was told that Luke thought as I did that BIP-110 needs more bite. @LukeDashjr On that you'd have to speak with him on his opinion. He and I are in different spheres.Image
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2. SegWit (Segregated Witness) was primarily developed and conceptualized by lead Bitcoin Core developers Pieter Wuille, Eric Lombrozo, and Johnson Lau. Wuille first presented the scaling upgrade at a Hong Kong conference in 2015, and it was subsequently integrated into the main protocol in August 2017. If you follow the trial it leads right to Runes/Ordinals. This is how I was clued into the play. This leads right to C-SAM and back to MIT and Epstein. Chaincode Labs is Wuille's baby.Image
3. The reason why people, including prominent developers, associated with the SegWit activation call it "unusual," "highly sketchy," or deeply controversial boils down to the fact that it was activated via a high-stakes political standoff, corporate backdoor agreements (MIT math and physics guys heavily involved), and an unprecedented game of economic chicken that nearly split the Bitcoin network in two.

Within Bitcoin’s technical community, the math behind SegWit was widely accepted. However, the actual activation process in 2017 bypasses normal software rollout consensus and is considered "sketchy" for several key reasons.
Read 18 tweets

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