James Throt MBBS, MD, PhD, FRCPath Profile picture
Mar 11 8 tweets 3 min read Read on X
In neurology/psychiatry, we would call this Apathy.

Brain damage to the frontal lobe (dorsal anterior cingulate cortex) causes apathy & reduces empathy.

SARS-CoV-2 damages this region of the brain. Every. Single. Time.

More infections = more damage = more apathy.

🧵
Increase in apathy is often seen in traumatic brain injury, stroke & dementia.

It manifests as a lack of motivation/enthusiasm due to disruption in the brain regions responsible for goal directed behavior & reward processing.

Resulting in a lack of drive to engage in activities
Apathy means having a lack of interest in activities once enjoyed.

Difficulty in initiating tasks.

Reduced motivation to engage in social interactions.

Feeling indifferent & unbothered.

Everything the OP & others are experiencing, with many assuming they just have ‘burnout’.
Be in no doubt, SARS-CoV-2 brain damage is very real.

Just because your initial illness was mild, or even asymptomatic, the virus is still in your brain, damaging it from within.

The thread below details what covid induced brain damage looks like & what we are already seeing. Image
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The most concerning thing from that QT is the sheer number of people believing feeling this way is perfectly normal. It isn’t.

Many people won’t realise they’re more apathetic than ever before. They’ll think they’ve always been like this, because brain damage causes anosognosia. Image
Am I suggesting ALL apathy is as a result of Covid infections? Absoutely not.

Am I suggesting Covid infections ALWAYS cause apathy? Absolutely not.

Do I think it relevant to mention, in an ongoing SARS-CoV-2 pandemic, that Covid induced brain damage causes apathy? Absolutely.
The attention that tweet gained seemed significant to me. It resonated w/huge numbers of people.

As a neurologist, I am all too aware that damage to this specific region of the brain OFTEN causes apathy.

Of course, covid might not be the cause here. But it sure as hell could be
Regardless of the cause, feeling that apathetic is certainly not normal & I stand by this.

If apathy is your ONLY issue right now, I’d wager it’s likely not covid.

If “brain fog”, or memory issues, or ⬆️ sickness, or new health issues are also present, it’s probably Covid.

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More from @JamesThrot

Mar 10
“They create the idea of a terrifying plague that will kill us all, when the truth is far less frightening”

The truth is SARS-CoV-2 likely won’t kill you today, nor tomorrow.

But it will damage the brain, internal organs, blood vessels & immune system of everyone it infects.
“Well covid did me no harm”

- You can lose up to 90% kidney function before experiencing any symptoms.

- Cancers often develop silently with symptoms only appearing at a more advanced stage.

- Blood clots develop silently.

- Brain damage often goes unnoticed by the sufferer.
An example regarding immune damage;

- Once infected with HIV, the time taken to develop AIDS is usually 10-15yrs.

- If people caught HIV in 2020, most would still be extremely fit & healthy with zero symptoms.

- HIV+ folk wouldn’t be sick every couple of months this early on.
Read 4 tweets
Mar 8
Does anybody else feel that blaming a few months of lockdown for ill health in 2025, both physical & mental, is not only disingenuous & delusional, but a crusade to spread disinformation?

The public lap it up so they can reassure themselves the threat has vanished into thin air.
We have outrageous hyperbole, as in the quoted tweet below, and almost everyone in the comments agree.

Peter is UK based, where lockdowns for the youngest children & those in year 6 lasted just 10 weeks, returning on 01/06/2020.

All other ages returned in September 2020. Image
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As previously stated, all other ages returned in September 2020, after the 6 week summer holiday period.

Lockdown started 23rd March 2020.

If we take away the time they’d have had off school for Easter and half-term, then all other ages missed a total of 14 weeks in school. Image
Read 12 tweets
Mar 5
You’re a bit late to the party guys.

I’ve been telling you this for years.

I’m sick of talking about the frontal lobe and the damage SARS-CoV-2 is inflicting upon it.

Personality changes, executive dysfunction, emotional lability, cognitive decline.

Welcome to the new normal.
As previously stated, personality changes will come before cognitive decline (intellect, memory, problem solving etc).

You don’t have to be a neurologist to see what’s happening to almost everyone around you.

SARS-CoV-2 almost always damages the brain of everyone it infects.
Always good to give this thread a read, discussing in more detail what you might start seeing in those around you, or even yourself.

Regardless of the severity or mildness of your covid infection/s, it’s getting into your brain.

It gets everywhere.

Respiratory virus? You wish.
Read 4 tweets
Mar 3
Have you developed symptoms of ADHD since 2020?

Or has your ADHD deteriorated since 2020?

The frontal lobe is the largest part of the brain affected by ADHD, often maturing at a slower pace with disrupted activity & connectivity.

Covid damages the frontal & temporal lobes.

🧵
I’m seeing far more people presenting with what they believe is ADHD, but I would suggest many of these cases are being misdiagnosed.

SARS-CoV-2 has been shown to reduce grey matter within the frontal/temporal lobes in the brain, and the damage goes far beyond simply being ADHD. Image
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ADHD is not degenerative, nor progressive, and symptoms should not worsen with age.

We haven’t yet ascertained whether Covid induced brain damage is progressive. But even if the damage was static, each new infection would cause new/worsening damage.

ADHD symptoms below ⬇️ Image
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Read 7 tweets
Mar 1
We are currently watching what I can only describe as the early stages of Frontotemporal Dementia on a mass scale playing out in real time.

The geopolitical ramifications of this are worrisome.

I am in no doubt about what I’m seeing.

The cause?

Ceaseless SARS-CoV-2 infections Image
Each new infection compounds the damage.

Damage to this area of the brain often causes ‘lack of insight’ (anosognosia ⬇️).

Self awareness is frequently impaired in FTD.

Tendency to act out of character often features.

Frontal lobe damage due to SARS-CoV-2 documented below ⬇️. Image
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FTD can cause increasing gullibility & worsening social cognition.

As previously stated, people with FTD usually don’t realise their symptoms/condition, i.e., blissfully unaware.

Appearing selfish or unsympathetic is common, as is loss of motivation & inappropriate behaviour. Image
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Read 6 tweets
Feb 28
Brief contact w/unmasked individual who tested + on LFT, whilst wearing an N95 myself.

I tested on LFT 2x per day for 3 weeks, all clearly negative.

No symptoms.

Antibody blood test 6 weeks later showed v high level of ABs. AB test 2 months prior - low levels.

I had Covid.
To be clear, I am NEVER unmasked around ANYONE.

It is of course possible I caught it elsewhere, it’s simply that that was the only known positive contact.

The point here is that I had a completely symptom free infection whilst testing consistently negative on LFTs.
So when you hear anyone say “it wasn’t covid”, even when they did LFTs religiously, you can’t be guaranteed that this is the case. It’s a sneaky virus.

Using LFTs, I thoroughly swab inside of cheeks, back of throat, and nostrils.

Nostrils alone is never enough.
Read 5 tweets

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