the temperature at which brains develop affects brain connectivity and behavior
lower temperatures lead to brains with over twice the connectivity and synaptic complexity
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lower temperatures lead to brains with over twice the connectivity and synaptic complexity
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new research from Johannes Gutenberg University, published in Science Advances, shows cooler developmental temperatures lead to significantly more complex neural wiring.
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temperatures dramatically influence the speed of development. previous studies suggested cooler conditions increased neural connectivity, but mechanisms and functional impacts were still unknown .
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the team studied Drosophila's olfactory system, using tools like trans-Tango labeling and optogenetics to map neural circuits across varied developmental temperatures.
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a novel metabolic model proposes neural growth and overall organism growth are governed by different metabolic rates, causing better neural connectivity at lower temperatures.
basically
hot T -> body grows faster, brain is smaller
low T -> body grows slower, brain is bigger
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basically
hot T -> body grows faster, brain is smaller
low T -> body grows slower, brain is bigger
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their data confirms that cooler temperatures enhance synapse number, size, and complexity by a lot, neurons developed at 18°C formed over double the connections seen at 25°C.
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what this means practically: lower temperature doesn’t just increase connectivity, it fundamentally changes neuronal communication, particularly improving neural pathways that regulate innate behaviors.
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more connections translate to improved overall function. odor encoding is stronger because increased synapses, downstream processing and signal interpretation are also significantly improved.
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developmental temperature doesn't simply alter the speed of growth, it generally reshapes the brain architecture and behavior, offering evolutionary advantages.
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the next research steps include expanding this analysis to additional brain regions and species, to verify if this metabolic-driven wiring principle is general, and understand the underlying metabolic constraints.
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these insights could change our understanding of developmental plasticity, informing new strategies for address neurodevelopmental disorders linked to early developmental environments.
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for those saying "peaters in shambles", this isn't anti-peat. cold boosts synapses because neural growth outpaces body growth specifically during development
once mature, peat's warmer metabolism still wins for health and performance
once mature, peat's warmer metabolism still wins for health and performance
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