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vittorio Profile picture
vittorio
@IterIntellectus
bio/acc –– ∞/acc — biology will rage against the dying of the light — don't take me seriously professional shitpoaster
10 subscribers
Oct 23 • 10 tweets • 3 min read
this was thought impossible just 2 years ago

now, AI built a working calcium ion channel from scratch, a synthetic molecular gate that conducts charge through living cells

this is the first building block of an artificial synapse
1/ Image for decades, we have only been able to design proteins that folded
but ion selectivity (distinguishing Ca²⁺ from Na⁺) was untouchable
it demands atomic control at ~0.2 Å precision. miss by one atom, and it doesn't work
2/
Sep 29 • 4 tweets • 1 min read
first cousin marriages double the risk of birth defects, shave ~10 iq points off the offspring, and their ban by the church was one of the biggest drivers of europe’s rise.
but sure, let’s go back to being fucking troglodytes i severely underestimated how bad things were in the UK
Sep 18 • 11 tweets • 2 min read
holy shit, it's happening

for the first time in history, AI *DESIGNED* a complete genome and it has been proven functional in the lab

1/ Image In 1977 the first bacteriophage genome (ΦX174, 5.4 kb) was sequenced, then in 2003 in was synthesized from chemicals and now Evo, a genome language model, designed new ΦX174-like genomes that actually worked in bacteria

From reading to writing to designing life
2/
Aug 21 • 10 tweets • 2 min read
72% who quit porn suffer withdrawal
it takes ~12 weeks for your brain to reset
1/ Image chronic high-stimulation triggers CREB protein. CREB then floods your system with dynorphin, your brain's internal brake pedal

dynorphin acts like an opioid that dampens dopamine. Your brain's way of saying "too much, slow down"

2/
Aug 19 • 12 tweets • 2 min read
your brain evolved to pair dopamine with oxytocin so people feel good.

porn gives dopamine without oxytocin and that's why relationships end
1/ Image your brain conditions itself to artificial superstimuli. Endless novel content over-stimulates dopamine pathways, creating unrealistic expectations for real partners.

2/
Aug 17 • 15 tweets • 3 min read
porn makes your wife invisible to your brain's reward system and it takes ~90 days to recover
1/ Image your brain remembers every porn binge for weeks through a molecular switch called δfosb

2/
Aug 15 • 10 tweets • 2 min read
watching porn literally shrinks your brain
1/ Image the numbers are brutal
correlation coefficient r≈-0.37 between porn consumption and actual brain matter
your pleasure center is literally getting smaller

2/
Aug 11 • 18 tweets • 2 min read
23% of men 18-35 now suffer from erectile dysfunction, 4× higher than 20 years ago
yes, it's porn
1/ Image internet porn acts as a "supernormal stimulus", like cocaine to a rat's brain. It floods your reward system with dopamine hits that nature never intended

2/
Aug 4 • 17 tweets • 3 min read
mild maternal iodine insufficiency steals 8-10 IQ points from your unborn child
🧵 Image this isn't random genetic lottery. This is programmed cognitive downgrade, installed before birth
conventional prenatal advice misses the core mechanism entirely

1/
Jul 25 • 14 tweets • 3 min read
every sperm you produce carries 74 days of molecular memory from your life

that beer gut isn't just yours anymore. obese fathers pass methylation changes that make their sons 47% more likely to be infertile

🧵1/13 Image you're not just passing DNA. you're passing software updates written by your diet, stress, and chemical exposure

these epigenetic instructions literally control which genes turn on in your child

2/13
Jul 22 • 6 tweets • 1 min read
nobody talks about how the internet killed regional culture.
everyone under 30 has the same personality now.

your grandparents' generation had accents, local customs, regional humor. you have tiktok trends and twitter discourse. we traded diversity for connectivity
gained the world, lost the neighborhood. everyone knows the same memes but nobody knows their neighbors.

previous generations moved cities to become different people. now you can't escape yourself. your digital footprint follows everywhere.
Jul 10 • 18 tweets • 3 min read
a hot room is probably the reason why your sleep sucks

1/ Image your thermostat is hijacking your circadian biology. not metaphorically. your SCN literally can't trigger proper sleep hormones when ambient temp stays constant

2/
Jul 8 • 19 tweets • 4 min read
15 minutes of sauna activates the exact same cellular repair pathways as 48 hours of fasting

1/ Image most people use saunas for relaxation or to detox through sweating which completely misses the real mechanism happening inside your cells where 15 minutes of heat stress triggers the same longevity pathway as 48 hours of fasting

2/
Jul 7 • 19 tweets • 3 min read
air conditioning is great, but it's also making you weaker
constant 70°F systematically deactivates two critical circuits hardwired into your DNA

1/ Image the real vulnerability isn’t the heatwave itself, but the lifetime of climate-controlled comfort that has silenced your body’s thermal adaptation circuits.

2/
Jul 1 • 19 tweets • 3 min read
drinking pure water makes you dehydrated because it gets rid of the minerals you need to get water in your cells
1/ Image you're drinking gallons of purified water and still dehydrated at the cellular level because modern hydration advice ignores the actual mechanism of how water enters cells through specialized protein channels called aquaporins

2/
Jul 1 • 32 tweets • 5 min read
today i turn 30, and as it goes, it' time for reflection

so here are 30 lessons i’ve learned so far
1/ 1-
 most of your life is decided 9 months before you were born, but what you do with it is on you

your genetics, family, and your environment are set before you’re born, not much you can do about it
but once you’re old enough to understand that, it’s all in your hands and you can do the most with it.
blaming others won’t save you. you have the responsability to do the best you can with what you have
Jun 30 • 19 tweets • 3 min read
losing just 2% of your body mass in water reduces your cognitive performance by 28% and your brain starts shrinking

1/ Image that 3pm brain fog that feels exactly like a hangover even when you've been good? it's not fatigue or low blood sugar

it's your brain cells physically shrinking because you're walking around in a state of chronic cellular dehydration and nobody talks about the mechanism

2/
Jun 25 • 16 tweets • 4 min read
holy shit, it’s here!

deepmind just released AlphaGenome.
an AI model that reads 1 million bases of DNA and predicts how any mutation changes molecular function

not just in single genes but across the entire regulatory genome.

DNA is code, and you are software
1/ Image oh yeah, and it's an API
github.com/google-deepmin…
Jun 24 • 18 tweets • 3 min read
scientists analyzed dust from 2,000 u.s. homes. 45 toxic chemicals in nearly every single one. 10 of these were in over 90% of samples. right now, you're breathing flame retardants from your couch. your body is absorbing them through your lungs and skin.

1/ Image these chemicals are endocrine disruptors leaching from your furniture, electronics, and flooring. every time you sit down, walk across carpet, or disturb dust, you're creating an aerosol of hormone-disrupting chemicals.

2/
Jun 21 • 21 tweets • 4 min read
women who had c-section have a 3mm thick web connecting the scar to their shoulder.
surgeons at mount sinai tracked 247 women post-surgery. 73% developed shoulder pain 2-7 years later. same side as the incision.
no injury. just physics.
1/ Image they used 3D ultrasound to watch what happens.
scar tissue forms a fascial dam - tissue 40% denser than surrounding areas. this creates a pull of 2.3 pounds of constant tension traveling up through your deep abdominal fascia.
2/
Jun 20 • 21 tweets • 3 min read
every time you do a bicep curl 30% of your strength is leaking sideways and ends up in your leg.
biomechanics researchers finally measured it only a couple of years back

your muscles don't behave like you think.
1/ Image university of queensland. 2021. 47 sensors on one lifter.
bicep curl. simple movement.
force appeared in the opposite calf.
2/