Crémieux Profile picture
Apr 3 13 tweets 10 min read Read on X
Timeline's feeling down. Thread of good news.

At every age, the incidence of dementia is down. As a society, people are no longer suffering dementia nearly as often! Image
The world over, child mortality is way down. It's unusual for parents to experience the death of a child these days, where even a century ago, it was the global norm. Image
Each year, novel gene therapies are approved.

The number of gene therapies in the pipeline is also rapidly increasing. There is tons of progress to be made here, and the main issue is regulatory.

We have lots of low-hanging fruit in curing disease! Image
Global tree cover has increased in recent years with the greening and reforestation of the globe.

This trend holds on almost every continent! Image
Globally, fewer and fewer people are dying from natural disasters.

The rates of natural disaster death nowadays are a small fraction of what they used to be. Image
Moore's Law has accurately described the evolution of the number of transistors per microprocessor, and even after this animation ends, it seems to have continued holding.
Though America's homicide recently skyrocketed in the days after George Floyd's death, the rate has since returned to normal and is back on track to keep falling. Image
Mandatory enrichment of cereal grain products with folic acid led to a decline in the number of babies born with neural tube defects in the U.S. Image
America's cancer death rates are up if you fail to acknowledge that the country has gotten older.

Once you acknowledge that people have gotten older, it becomes apparent that America's cancer death rates have substantially declined! Image
When countries run campaigns to teach parents how to position their babies when they sleep, the result is typically a considerable reduction in SIDS death rates in just a few years. Image
It's true that people are getting fatter and fatter, but our medical system has kept up.

Despite rising obesity, cardiovascular disease is claiming fewer and fewer lives at each age. Image
There's more good news out there.

Every day, diseases are cured and prevented, people are losing weight, babies are born healthier than they've ever been, people get richer and their lives become more manageable, and more.

Day-to-day, things may seem hard, but progress is real!
Sources below.

Dementia:

Source: alzforum.org/news/research-… (Possible non-exciting explanation: More people are surviving to old age now, so maybe people who wouldn't have survived previously are disposed to lower dementia rates.)

Archive: archive.md/9RW41

Replication in Sweden: academic.oup.com/biomedgerontol…

Replication in England: sciencedirect.com/science/articl…

Related, supporting multi-country work: x.com/cremieuxrecuei…

Supportive German evidence: journals.sagepub.com/doi/full/10.11…

Evidence against this being due to education: journals.sagepub.com/doi/full/10.11…, psycnet.apa.org/doiLanding?doi…

Data showing that, despite falling age-specific incidence, prevalence is still up because the population is getting older: bmj.com/content/358/bm…, sciencedirect.com/science/articl…

Child mortality:

Source: ourworldindata.org/grapher/child-…

Gene therapy:

Source: healthadvances.com/insights/blog/…

Archive: archive.md/WDuVB

Tree cover:

Source: humanprogress.org/trends/more-la…

Archive: archive.md/gyMtj

Natural disaster deaths:

Source: humanprogress.org/trends/a-safer…

Archive: archive.md/XjTVK

Moore's Law:

Source: reddit.com/r/dataisbeauti…

Archive: archive.md/TIWyA

More: ourworldindata.org/data-insights/…

Homicide: See CDC WONDER and my previous posts on the Floyd Effect.

Neural tube defects:

Source: pmc.ncbi.nlm.nih.gov/articles/PMC45…

Age-standardized cancer death rates:

Source: ourworldindata.org/grapher/cancer…

More: blogs.cdc.gov/nchs/2021/09/1…

SIDS:

Source: direct.mit.edu/rest/article-a…

Cardiovascular disease:

Source: ourworldindata.org/data-insights/…

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More from @cremieuxrecueil

Apr 16
Compared to twenty years ago, kids are eating some types of ultraprocessed foods more and some types less🧵

For example, one thing there's proportionally less of is sugar-sweetened beverage consumption. Meanwhile, there's relatively greater sweet snack consumption. Image
Overall, the ultraprocessed food (UPF) consumption share is up across young ages to similar degrees.

The increase is definitely there, but it isn't dramatic. For example, going from 61% to 67.5% is an 11% increase in twenty years. Image
The increase in consumption is not differentiated by the sex of children.

In other words, boys and girls are both eating a bit more ultraprocessed food. Image
Read 14 tweets
Apr 16
Today the President has provided an outline for the direction of medication pricing over the next four years.

This is related to broader deregulatory efforts that are likely going to end up making Americans a lot better off🧵 Image
The executive order starts off by noting the administration's efforts to reduce drug prices the first time around.

These efforts were centered around deregulation and promoting transparency in the concentrated, often-cartelized and captured healthcare marketplace. Image
A few days ago, an opinion piece by @ezraklein went out in the @nytimes.

It described how people in the Biden administration wished that they'd just gone a little faster.

It's good they believe this, because it's true: they went very slowly.Image
Read 19 tweets
Apr 14
The Flynn Effect🧵

People tend to understand it as an indication that earlier generations were a lot less intelligent than we moderns.

Or if they're read up on the literature, they now think things are reversing.

Both are wrong! Take a look at this chart of Norwegian data: Image
If you don't understand what those tests are like, here are some example questions: Image
What we see over time with the Flynn Effect (the increase in IQ scores) and the Reverse Flynn Effect (the more recent decrease in IQ scores) is that both are due to something really boring: people interpreting tests differently than they used to.
Read 8 tweets
Apr 13
A new UBI experiment has come out.

This time... it seems like it worked🧵 Image
The study took place in Germany and was centered on the experiences of 107 people aged 21-40 who lived alone and had earnings between €1,100 and €2,600 per month.

The experiment provided them with €1,200 per month for three full years. Image
Controls (N = 1,580) earned €10 for sticking with the program and another €30 if they made it the whole way.

There was no attrition in the treatment group, but 29% of the control group dropped out by the end of the study.

Attrition seemed unselective. So onto results!
Read 23 tweets
Apr 11
Many women have found that they get pregnant more easily after getting on GLP-1 drugs.

But women aren't the only ones noticing improved fertility:

There's now clinical trial evidence that GLP-1s improve sperm parameters. Image
The largest clinical trial published so far on this subject came out in 2023. It involved 110 men aged 18-35 with metabolic hypogonadism being sorted into one of three conditions:

A: The group seeking fatherhood.
B: The group not seeking fatherhood.
C: The group of already-dads.
The men in Group A were explicitly given the fertility drugs urofollitropin three times a week and human chorionic gonadotropin twice a week.

Group B received the GLP-1 drug liraglutide.

Group C received daily transdermal testosterone.

This goes on for four months. Image
Read 21 tweets
Apr 9
A brilliant new paper found that brain drain can literally kill🧵

The paper is all about what happened when Sweden's doctors decided to pack up their stethoscopes and scalpels and go to work in another country. Image
The story begins with the curious economic divergence of Norway and Sweden.

Over time, Norway has become vastly richer than Sweden primarily because it's become Europe's premiere petrostate.

With surging oil prices, their GDP leaped ahead at a staggering pace: Image
With rising wages due to the oil sector, wages elsewhere in the economy have to rise, even in sectors that didn't get more productive

If those wages didn't rise, no one would want to do those jobs: Butlers in different countries equally butle, but are paid very different amounts Image
Read 16 tweets

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