Nicholas Fabiano, MD Profile picture
May 1 8 tweets 2 min read Read on X
72 hours without your phone rewires neural pathways tied to impulse control and reward.

🧵1/8 Image
These findings are from a study in @ELSpsychology which used a functional MRI (fMRI) to investigate the effects of smartphone restriction over 72 h in 25 young adult smartphone users. 2/8 sciencedirect.com/science/articl…Image
With the increasing popularity of smartphones in the past decades, physical, social, and psychological consequences of excessive smartphone use (ESU) have been increasingly debated. 3/8
Cue-reactivity (CR) has been discussed as a core mechanism driving this behavior, and previous studies have highlighted distinct neural mechanisms underlying CR in individuals with ESU. 4/8
The CR-task used contrasts of images showing smartphones vs. neutral stimuli and active vs. inactive smartphones. 5/8 Image
CR-related brain activity changes over time were most prominent in the nucleus accumbens and anterior cingulate cortex (p < 0.001). 6/8
Such changes were significantly associated with dopamine- and serotonin-receptor probabilities, with significant associations between parietal cortex activity and craving detected. 7/8
Overall, this study provides evidence for CR-related modulation of neural activity in key regions of salience, motor-inhibition, and reward processing after 72 h smartphone restriction. 8/8

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Nicholas Fabiano, MD

Nicholas Fabiano, MD Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @NTFabiano

Apr 29
Exercise leads to the release of myokines, increasing neuron growth by 4x.

🧵1/10 Image
These findings are from a study in @WileyGlobal which examined the impact of myokines, released during exercise, on neuron growth. 2/10 advanced.onlinelibrary.wiley.com/doi/10.1002/ad…Image
Exercise can impact the morphology/function of a range of tissues including muscle, bone, fat, vasculature, immune cells, and the nervous system, but the mechanisms by which physical activity regulates inter-tissue communication are still poorly understood. 3/10
Read 10 tweets
Apr 27
Light treatment had the same effect as an antidepressant - with earlier response and less side effects.

🧵1/9 Image
These findings are from a study in @APA_Journals which compared the effectiveness of light therapy and an antidepressant for the treatment of seasonal affective disorder. 2/9 psychiatryonline.org/doi/10.1176/aj…Image
Seasonal affective disorder is the term applied to a clinical subtype of mood disorder that consists of recurrent episodes of major depression occurring with a seasonal pattern. 3/9
Read 9 tweets
Apr 26
Severe exercise reversibly reduces brain myelin content.

Myelin lipids may act as glial energy reserves in extreme metabolic conditions.

🧵1/12 Image
These findings are from a study in @NatMetabolism which used magnetic resonance imaging to study the impact of marathon running on brain structure in humans. 2/12 nature.com/articles/s4225…Image
Prolonged endurance exercise mobilizes energy stores throughout the body to meet energy demands; marathon runners primarily rely on carbohydrates as the main energy source during a race. 3/12
Read 13 tweets
Apr 25
Psilocybin led to increased brain complexity & spontaneous behaviour in a person with a post-comatose disorder of consciousness.

🧵1/10 Image
These findings are from a case report in @ClinicalNeuroph which describe the first-ever administration of psilocybin, a classic psychedelic, to a patient in a minimally conscious state. 2/10 sciencedirect.com/science/articl…Image
With very few treatments available, post-comatose disorders of consciousness (DoC) pose one of the hardest challenges in modern neurology. 3/10
Read 11 tweets
Apr 23
The amygdala is a brain region involved in stress.

Resting metabolic activity of the amygdala significantly predicts the development of cardiovascular disease.

🧵1/10 Image
These findings are from a study in @TheLancet which aimed to determine whether resting metabolic activity of the amygdala predicted risk of subsequent cardiovascular events. 2/10 thelancet.com/journals/lance…Image
Stress prompts activation of both the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis, leading to increases in circulating catecholamines, glucocorticoids, and (eventually) inflammatory cytokines. 3/10 Image
Read 10 tweets
Apr 21
Why do living organisms need sleep?

A new theory suggests that myelin acts as a proton capacitor, accumulating energy during sleep.

🧵1/12 Image
These findings are from a paper in @ElsevierConnect which discussed a novel hypothesis as to why living organisms need sleep. 2/12 sciencedirect.com/science/articl…Image
Myelin is formed by specific glial cell types (oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system) that generate a multilayer sheath around nerve cell axons. 3/12 Image
Read 12 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(