π₯1 in 180 actively infectious
π₯1.9 million weekly infections
π₯>93,000 new #LongCOVID cases from the week's infections
π₯1,100 excess deaths from the week's infections
This is a "lull."
2) PMC Dashboard, May 26, 2025 (U.S.)
The forecast calls for a near-doubling in transmission the next month to 450k daily infections.
The 95% confidence interval includes flat transmission (percolating), or escalating to 650k (if NB.1.8.1 takes off).
3) PMC Dashboard, May 26, 2025 (U.S.)
Looking at year-over-year transmission, 2025 (red) is closely tracking the median (gray).
It transmission accelerates, it could look more like last year (orange). If it slows, more like two years ago (yellow).
4) PMC Dashboard, May 26, 2025 (U.S.)
Note that we are exiting the relative "lull" following the 10th wave in the U.S.
Let it sink in that this week's lull infections will likely result in about 1,100 deaths. Then, consider the 11th wave on the way.
5) PMC Dashboard, May 26, 2025 (U.S.)
The CDC defines the vast majority of the U.S. in "low" or "very low" transmission.
This may be true in relative comparisons, but the excess deaths remain high in an absolute sense.
Monthly Covid excess deaths surpass 9/11.
6) PMC Dashboard, May 26, 2025 (U.S.)
Regional data show the lull likely ending with the West already in an apparent uptick.
SARS-CoV-2 transmission has fallen.
πΉ1 in 191 (0.5%) actively infectious
πΉ"Lull" levels at 20% of the summer peak
πΉ255,000 new daily infections (still concerning)
Many will knock out higher-risk activities the next 2-4 weeks.
π§΅1/11
PMC COVlD Update, Oct 20, 2025 (U.S.)
"Lull" transmission remains dangerous:
πΉ1.8 million estimated new weekly infections
πΉ>90,000 estimated new #LongCOVID conditions from this week's infections
πΉ>500 excess deaths to result from this week's infections
π§΅2/11
PMC COVlD Update, Oct 20, 2025 (U.S.)
Exposure risk during "lull" transmission remains high when engaging in many social interactions.
Interacting with 25 people yields a 12% chance of exposure. 100 people? 41% chance of exposure, assuming no testing/isolation.
PMC COVlD Wave Update (Europe)
11 October 2025 π§΅
The PMC website includes an international directory of websites with COVlD wastewater monitoring. It is more up to date than the directories of the EU and WHO.
Let's review what's happening in Europe...
1/
Data in #Austria show a rising COVlD wave. The x axis (bottom) has infrequent labels, but the data shown go through October 8th.
PMC COVlD Update, Week of Oct 6, 2025 (U.S.)
π§΅1/9
An estimated 1 in 81 people are actively infectious during the ongoing 11th wave.
The "shutdown" has created a blackout at the state level.
Transmission is half that of the peak one month ago, and we anticipate a relative national "lull" in early-to-mid November, albeit still at dangerous levels.
Our model uses a combination of CDC and Biobot data, so we are able to estimate national statistics despite the CDC data going offline. On the map, note that Puerto Rico continues to update; they use a CDC-style system but were dropped by the CDC long ago. For full methodology, review the technical appendix on the website.
PMC COVlD Update, Week of Oct 6, 2025 (U.S.)
π§΅2/9
#DuringCOVID is today. We estimate >600,000 new daily infections. This is about half the peak on September 6.
Notice current levels are similar to the estimated peaks of the first 3 waves.
PMC COVlD Update, Week of Oct 6, 2025 (U.S.)
π§΅3/9
Weekly estimates:
πΉ4.5 million infections
πΉ>200,000 resulting long-term health conditions
πΉ>1,300 resulting excess deaths
Key points in my letter to the pharmacy boards. π§΅1/7
Georgia law indicates that the pharmacy board is to follow ACIP. They do not dictate further nuance. Georgia continues to require prescriptions, going against the spirit of the law, ACIP, and 47 other states.
π§΅2/7
Louisiana law tells the pharmacy board to follow ACIP. ACIP says do not require a prescription, and 47 other states agree.
The Louisiana pharmacy board continues to require a prescription.
On the back end of this unprecedented 11th wave, "times they are a-changin." In particular, COVlD levels are shifting north and east.
Notice that few states are in the highest and lowest categories. Much of the south and west have considerable transmission post-peak. Many places in the north and east are seeing steady or increasing transmission after relatively lower levels.
Overall, levels are lower than the past few weeks, but transmission remains considerable. Those relying on anecdata (friends, coworkers, and family infected) may increasingly realize we are in a wave.
We estimate nearly 750,000 new daily infections nationwide, meaning approximately 1 in 66 people or 1.5% are actively infectious.
These estimates are derived by linking wastewater levels to IHME true case estimates using methodology commonly employed worldwide, detailed on the website, noted in a pre-print. Many publications in leading medical journals link wastewater data to key metrics that matter, noted in the online technical appendix.
In this week's report, we note adding North Dakota and Puerto Rico to the heat map in support of health equity. We have been imputing ND levels since the launch of PMC 3.0 using data from neighboring states. PR continues to report qualitative levels using the CDC format but is not longer included on the CDC website.
1/8 π§΅
PMC COVlD Update, Sep 29, 2025 (U.S.)
State-level prevalence estimates, AL to MS. The levels use CDC labels, which tend to have an optimistic portrayal of risk. For example, CO is listed at "low" (by our estimate 1.5% infectious).
#MaskUp at 1.5% if having lapsed.
2/8 π§΅
PMC COVlD Update, Sep 29, 2025 (U.S.)
State-level prevalence estimates, Missouri to Wyoming.
New York had *huge* retroactive upward corrections, and is now "High," as many residents hypothesized.
Note, Puerto Rico only provides CDC qualitative levels, so no data.