2/ This paper shows autonomous driving follows the same scaling laws as the rest of ML - performance improves predictably on a log linear basis with data and compute
This is no surprise to anybody working on LLMs, but it’s VERY different from consensus at Waymo a few years ago
3/ Waymo built its tech stack during the pre-scaling paradigm. They train a tiny model on a tiny amount of simulated and real world driving data and then finetune it to handle as many bespoke edge cases as possible
This is basically where LLMs back in 2019
4/ The bitter lesson in LLMs post 2019 was that finetuning tiny models on bespoke edge cases was a waste of time. GPT-3 proved if you just to train a 100x bigger model on 100x more data with 10,000x more compute, all the problems would more or less solve themselves!
5/ If the same thing is true in AV, this basically obviates the lead that Waymo has been building in the industry since the 2010s. All a competitor needs to do is buy 10x more GPUs and collect 10x more data, and you can leapfrog a decade of accumulated manual engineering effort
6/ In contrast to Waymo, it’s clear Tesla has now internalized the bitter lesson
They threw out their legacy AV software stack a few years ago, built a 10x larger training GPU cluster than Waymo, and have 1000x more cars on the road collecting training data today
7/ I’ve never been that impressed by Tesla FSD compared to Waymo. But if Waymo’s own paper is right, then we could be on the cusp of a “GPT-3 moment” in AV where the tables suddenly turn overnight
The best time for Waymo to act was 5 years ago. The next best time is today!
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1/ Was this the biggest miss in the history of pharma? Apparently in 1990, Pfizer preemptively abandoned development of the first GLP1 drugs
Ozempic, Zepbound, Wegovy, Mounjaro, etc. were doing $60B+ in runrate revenues at the end of last year. None are made by Pfizer
2/ Source is this retrospective written by Jeffrey Flier (former dean of Harvard Medical School) about his biotech startup MetaBio in the late 1980s: muse.jhu.edu/article/936213
3/ MetaBio was founded in 1987. That was the year Joel Habener first reported GLP-1’s ability to stimulate glucose-dependent insulin secretion - in retrospect, the moment of “discovery” for GLP-1s
MetaBio became the first company in the world to license Habener’s GLP-1 patents
1/ If you really believe LLMs will dramatically compress the cost of software development in 3-5 years, doesn't this obviate the reason for independent software vendors to exist?
This doesn't seem obviously crazy to me - it'd just be a return to the days of mainframes
2/ When IBM invented the mainframe in the 50s, there were no independent software companies - IBM bundled their hardware with a COBOL compiler, which customers then used to write custom software themselves
3/ The world's first independent software vendors (e.g. ADR, Informatics, MSA) all started in the 60s as contract programmers - basically, consultants hired to write custom COBOL for clients - who then realized they could resell that custom code to multiple customers
1/ This internal 2007 Nokia presentation on the first iPhone is a really good example of how incumbents actually get disrupted
Oftentimes, the incumbent already knows what needs to be done. It's just that organizational incentives inhibit the incumbent from doing it
2/ This slide deck was posted on Hacker News earlier this week but just got taken down
I have no idea how they got their hands on a copy but it does look like a legit internal Nokia presentation from strategy team at the timenews.ycombinator.com/item?id=427247…
3/ Contrary to popular belief, people at Nokia in 2007 understood that the iPhone was a big deal
The iPhone's touchscreen would "set a new standard of state-of-art"
Nokia's own user interface paradigm was "in decline"
1/ I just finished a 2.5 week trip through China today, my first visit in about a decade. I was there for family reasons, but it also happened to be my first time in the country as a tech industry observer
My amateur travel journal on the China tech market -
2/ OBSERVATION #1 - Yes, everything really does run on WeChat
If you're a foreign traveler visiting China, you really must set up WeChat Pay and Alipay beforehand. For me, this was the Chinese equivalent of Whatsapp + Chrome + Venmo + my credit card + my subway card + Doordash
3/ I didn't use cash a single time on my 19 day trip. Everybody took WeChat Pay, from Michelin-starred restaurants, to McDonalds, to butchers at the farmers markets in tier 3 cities, to performing musicians in national parks
1/ Just caught up with a few investor friends in the consumer space last week about Ozempic and GLP1s
As far as I can tell, everything basically hinges on: how much does it matter that every consumer product in the world depends on a tiny cohort of super consumers?
2/ What happens if it turns out we’ve actually invented an all-purpose anti-addiction drug?
I suspect it’s not properly appreciated how many consumer categories follow a power law distribution of consumptiontheatlantic.com/health/archive…
3/ The top 9% of US adults account for 34% of US candy consumption