James Throt MBBS, MD, PhD, FRCPath Profile picture
Jul 17, 2025 24 tweets 6 min read Read on X
Let’s talk about COVID, brain damage & society.

Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?

This thread is for the skeptics.

I’m a neurologist, stay with me 🧵 Image
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@Daithiunjabbed Studies that show SARS-CoV-2 causes disease:

nature.com/articles/s4159…

nature.com/articles/s4158…
@Daithiunjabbed Want a one-paper silver bullet that isolates, characterises & causes disease in one neat package?

That’s not how real science works. But you wouldn’t know this, being intellectually challenged.

It happens cumulatively, across multiple rigorous studies, all of which now exist.
@JN1171 The problem?

Our data systems weren’t built to track a slow, mass cognitive shift.

But the behavioural signal is there; clear, global, and exactly what you’d expect from repeat frontal lobe injury.
@SnoopDougieDoig What stands out is the sudden acceleration in things like youth violence, attention deficits, and empathy decline after the mass global spread of brain damaging SARS-CoV-2.

If phones were the root cause, we’d expect a more gradual, linear trend. Not this sharp, post 2020 curve.
@JjudgeThe77524 @JN1171 Image
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@JjudgeThe77524 @JN1171 Image
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@Kristy718028917 High spike antibody levels in the vaccinated = strong immune response.

That’s not the same as viral replication, tissue damage, or CNS invasion like actual covid causes.

Conflating immune signal with pathology is how misinformation spreads.
@cfd4441 @EmilyPetro22 If by ‘pushing that trash’ you mean correcting misinformation with evidence, then yes, I’m guilty. Sue me.

Sorry that facts feel like a personal attack.

Maybe sit with that.
@Kristy718028917 The spike from the vax is transient, localised, and degraded quickly.

SARS-CoV-2 infection, not vaccination, is strongly linked to lasting neurological damage, including direct invasion, inflammation, microclots & hypoxia.
@Kristy718028917 Comparing vaccine effects to viral brain injury ignores critical differences in mechanism & severity.

Spreading false equivalences like this fuels misinformation and fear rather than science-based understanding.
@rusty_ricochet The virus causes documented, widespread neurological harm.

The vaccine does not replicate, does not contain nucleocapsid protein, and has nowhere near the same pathological footprint.

You’re blaming the seatbelt for the car crash. And it’s f*cking tiresome.
@EvalEvan66 And as for “it’s not relevant in 2025”, the virus is still spreading, still crossing the blood-brain barrier, and still triggering neuroinflammation.

What’s changed is the willful ignorance.
@kristy_warrior @Kristy718028917 Most biodistribution data show spike production is transient, mostly in muscle & lymph nodes, and cleared fast.

Unlike the live virus, which replicates, crosses the BBB, causes inflammation, cell damage, and brain shrinkage.

This is boring now. Blocked.
@AJonSchultz @GVDBossche @VigilantFox The evidence overwhelmingly supports mRNA vaccine safety and efficacy.

Healthy skepticism is good, but it has to be based on data, not vibes, nor on farming for engagement.
Frontal lobe dysfunction shatters critical thinking.

That’s how you go from understanding public health to believing vaccines are more dangerous than the virus, every expert is lying, & your YouTube search counts as research.

Thank you for providing very convincing case studies
@AnnieMcnei41751 Persistent anosmia has been linked to increased risk of neurodegenerative diseases like Parkinson’s & Alzheimer’s.

Brain imaging shows structural loss in areas tied to memory, emotion, and executive function.
Credit for the olfactory cortex image goes to @DaniBeckman

Thank you for your work and for flagging the omission, a terrible oversight on my part.

My apologies.
@jamesrcole If you can’t grasp basic scientific concepts like probability versus determinism, maybe stop wasting time debating and educate yourself first.

This isn’t difficult, it’s fundamental to critical thinking.
@TepperHerb2025 In contrast, SARS-CoV-2 infection has extensive evidence of brain injury: grey matter loss (Douaud et al., 2022), neuroinvasion (Matschke et al., 2020), and long term neuropsychiatric effects.

Vaccination reduces these risks, your talking points ignore this entirely.
@ClareQ12 It’s plausible the virus had neuroinvasive properties, contributing to long term brain effects in survivors & possibly influencing post pandemic societal and health impacts.
@GG2763048772993 Long term, difficulties in forming healthy relationships, increased susceptibility to misinformation, challenges in educational achievement & greater risk for behavioral disorders. Early FL disruption may also predispose to mental health issues and diminished societal cohesion.
@NeurologistMom @DaniBeckman Those thousands of images are SARS-CoV-2 related. And when searching for appropriate ones for threads and Twitter posts, I’m clearly sometimes not selecting the correct screenshot/images. That’s my fault.

As I say, I’ve apologised.

Surely you saw I’ve since credited?

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More from @JamesThrot

Mar 18
Because COVID has caused so many health problems for so many people, they’re inundated with patients demanding help for their new ailments.

And because nobody, including doctors, wants to acknowledge COVID, it’s more convenient to label the myriad of health problems as “anxiety”
“My new issue that just so happened to appear post-2020 is nothing to do with COVID”

Maybe not.

But repeated infections w/a virus that is vasculotropic, neurotropic, cardiotropic, thromboembolic, oncogenic & damages the immune system certainly won’t be beneficial to your health
I increasingly suspect a feedback loop is emerging in medicine.

People develop health problems after SARS-CoV-2 infection, but neither the patient nor the doctor wants to raise COVID as a possible factor.

So it quietly disappears from the diagnostic conversation.
Read 11 tweets
Mar 15
Two students at the University of Kent in the UK have died following an outbreak of "invasive" meningitis.

A further 11 students are currently in hospital and reported to be seriously ill.

All normal on plague island during a never-ending SARS-CoV-2 pandemic. Image
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It’s worth knowing that COVID has been associated with T-cell exhaustion, lymphopenia, impaired interferon responses & persistent immune dysregulation.

When host immune regulation is altered, susceptibility/vulnerability to other infections, like meningitis, can increase.
Pathogens responsible for meningitis, like Neisseria meningitidis & Streptococcus pneumoniae, often take hold when immune defenses are impaired.

If SARS-CoV-2 can dysregulate immune function, the downstream effects on vulnerability to infections need acknowledging.
Read 7 tweets
Mar 8
Spreading a brain damaging virus on repeat for >6 years won’t be helping

And since nobody has an appetite for avoiding brain damage, there’s no end in sight

Pretending your 8th COVID infection is just another cold won’t protect you either

Actions & inactions have consequences
Frontal lobes refine behaviour. COVID damages them.

They regulate impulse control, empathy, moral reasoning & judgment.

Damaged lobes mean someone can remain articulate & knowledgeable while becoming reckless, cruel, suggestible & catastrophically bad at evaluating consequences
Executive function is also degraded.

Intelligence without executive function is dangerous. You can be sharp, knowledgeable, eloquent… and still impulsively destroy lives, misjudge catastrophes, or follow urges with zero moral compass.

The brain’s brakes & filters are gone.
Read 6 tweets
Mar 7
MAGA has gone full throttle at attempting to smear me and claim I am unequivocally incorrect in my suggestion Trump may have FTD

Exhibit A below ⬇️

These are not the words of a world leader with fully functioning frontal lobes

His internal filter is progressively diminishing Image
MAGA has been hanging off every word of a dementia patient. No matter how ridiculous or how unhinged it became. They followed. They regurgitated. They worshipped.

The baseline for what constitutes normal behaviour has continually shifted into increasingly preposterous territory.
Imagine having to reckon with the fact you were hoodwinked, beguiled & cajoled by a cognitively compromised senior citizen w/progressive brain atrophy. This won’t sit well.

Under normal circumstances this individual would be in a memory care facility.

But instead, they’re POTUS
Read 5 tweets
Mar 5
As a neurologist, I’ve dealt with Frontotemporal Dementia (FTD) patients for years

I often pondered how diabolical it would be if a world leader suffered the same fate

Now I’m seeing it play out in real time

Without impeachment, this will get darker than you could ever imagine
Frontotemporal dementia attacks the frontal lobes. The brain’s command center for judgment, empathy, impulse control, moral reasoning and long-term planning.

Imagine a world leader whose frontal lobes progressively fail, but no one intervenes.

Or worse, they cheer it on.
As FTD progresses, disinhibition dominates.

The leader may issue impulsive orders, make erratic public statements or flout norms & laws.

Even in those who were previously unmalicious, there would be a genuine neurological inability to foresee consequences.
Read 17 tweets
Mar 3
When you realise that frontal lobe dysfunction lowers resistance to manipulation & propaganda

And that aging leads to frontal decline, affecting how seniors vote

You’ll understand why the uncontrolled spread of a virus, well documented to damage the frontal lobes, is encouraged
Why?

Reduced prefrontal cortical function, whether from injury, aging or temp impairment, is associated with decreased critical evaluation, increased impulsivity & greater reliance on emotionally salient narratives, which can increase vulnerability to manipulation & propaganda.
A society’s resistance to propaganda depends on the cognitive health of its population.

If executive function declines at scale, you end up with worse decisions on an individual basis, and weaker collective judgment.

And SARS-CoV-2 is the virus that corrodes executive function.
Read 6 tweets

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