James Throt MBBS, MD, PhD, FRCPath Profile picture
Jul 17 24 tweets 6 min read Read on X
Let’s talk about COVID, brain damage & society.

Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?

This thread is for the skeptics.

I’m a neurologist, stay with me 🧵 Image
Image
Image
Image
@Daithiunjabbed Studies that show SARS-CoV-2 causes disease:

nature.com/articles/s4159…

nature.com/articles/s4158…
@Daithiunjabbed Want a one-paper silver bullet that isolates, characterises & causes disease in one neat package?

That’s not how real science works. But you wouldn’t know this, being intellectually challenged.

It happens cumulatively, across multiple rigorous studies, all of which now exist.
@JN1171 The problem?

Our data systems weren’t built to track a slow, mass cognitive shift.

But the behavioural signal is there; clear, global, and exactly what you’d expect from repeat frontal lobe injury.
@SnoopDougieDoig What stands out is the sudden acceleration in things like youth violence, attention deficits, and empathy decline after the mass global spread of brain damaging SARS-CoV-2.

If phones were the root cause, we’d expect a more gradual, linear trend. Not this sharp, post 2020 curve.
@JjudgeThe77524 @JN1171 Image
Image
Image
Image
@JjudgeThe77524 @JN1171 Image
Image
Image
@Kristy718028917 High spike antibody levels in the vaccinated = strong immune response.

That’s not the same as viral replication, tissue damage, or CNS invasion like actual covid causes.

Conflating immune signal with pathology is how misinformation spreads.
@cfd4441 @EmilyPetro22 If by ‘pushing that trash’ you mean correcting misinformation with evidence, then yes, I’m guilty. Sue me.

Sorry that facts feel like a personal attack.

Maybe sit with that.
@Kristy718028917 The spike from the vax is transient, localised, and degraded quickly.

SARS-CoV-2 infection, not vaccination, is strongly linked to lasting neurological damage, including direct invasion, inflammation, microclots & hypoxia.
@Kristy718028917 Comparing vaccine effects to viral brain injury ignores critical differences in mechanism & severity.

Spreading false equivalences like this fuels misinformation and fear rather than science-based understanding.
@rusty_ricochet The virus causes documented, widespread neurological harm.

The vaccine does not replicate, does not contain nucleocapsid protein, and has nowhere near the same pathological footprint.

You’re blaming the seatbelt for the car crash. And it’s f*cking tiresome.
@EvalEvan66 And as for “it’s not relevant in 2025”, the virus is still spreading, still crossing the blood-brain barrier, and still triggering neuroinflammation.

What’s changed is the willful ignorance.
@kristy_warrior @Kristy718028917 Most biodistribution data show spike production is transient, mostly in muscle & lymph nodes, and cleared fast.

Unlike the live virus, which replicates, crosses the BBB, causes inflammation, cell damage, and brain shrinkage.

This is boring now. Blocked.
@AJonSchultz @GVDBossche @VigilantFox The evidence overwhelmingly supports mRNA vaccine safety and efficacy.

Healthy skepticism is good, but it has to be based on data, not vibes, nor on farming for engagement.
Frontal lobe dysfunction shatters critical thinking.

That’s how you go from understanding public health to believing vaccines are more dangerous than the virus, every expert is lying, & your YouTube search counts as research.

Thank you for providing very convincing case studies
@AnnieMcnei41751 Persistent anosmia has been linked to increased risk of neurodegenerative diseases like Parkinson’s & Alzheimer’s.

Brain imaging shows structural loss in areas tied to memory, emotion, and executive function.
Credit for the olfactory cortex image goes to @DaniBeckman

Thank you for your work and for flagging the omission, a terrible oversight on my part.

My apologies.
@jamesrcole If you can’t grasp basic scientific concepts like probability versus determinism, maybe stop wasting time debating and educate yourself first.

This isn’t difficult, it’s fundamental to critical thinking.
@TepperHerb2025 In contrast, SARS-CoV-2 infection has extensive evidence of brain injury: grey matter loss (Douaud et al., 2022), neuroinvasion (Matschke et al., 2020), and long term neuropsychiatric effects.

Vaccination reduces these risks, your talking points ignore this entirely.
@ClareQ12 It’s plausible the virus had neuroinvasive properties, contributing to long term brain effects in survivors & possibly influencing post pandemic societal and health impacts.
@GG2763048772993 Long term, difficulties in forming healthy relationships, increased susceptibility to misinformation, challenges in educational achievement & greater risk for behavioral disorders. Early FL disruption may also predispose to mental health issues and diminished societal cohesion.
@NeurologistMom @DaniBeckman Those thousands of images are SARS-CoV-2 related. And when searching for appropriate ones for threads and Twitter posts, I’m clearly sometimes not selecting the correct screenshot/images. That’s my fault.

As I say, I’ve apologised.

Surely you saw I’ve since credited?

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with James Throt MBBS, MD, PhD, FRCPath

James Throt MBBS, MD, PhD, FRCPath Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @JamesThrot

Jul 30
🧵 Thread: Why don’t people take COVID seriously in Year 6 of the pandemic?

A virus that disables the immune system, damages the brain, heart, and vasculature.

And spreads like smoke.

Yet the world shrugs.

Why?

Because mass denial is doing what it always does.

1/18 Image
Image
Image
Image
When a threat is chronic, invisible, and socially inconvenient, people don’t rationally evaluate it, they emotionally suppress it.

Denial becomes a survival mechanism. Especially in societies offering zero support for caution, it’s easier to numb out than face reality.

2/
This denial is socially rewarded.

If you mask, you’re weird.

If you talk about COVID, you’re exhausting.

If you stay home sick, you’re overreacting.

People protect their comfort and status by mirroring the crowd, even if the crowd is sleepwalking off a cliff.

3/
Read 21 tweets
Jul 14
The following question has been on my mind. So to the covid cautious community, I ask:

If you know that the virus, SARS-CoV-2, is harmful, persistent and disabling, why do some of you still participate in systems, relationships, behaviours, and events that perpetuate its spread?
Many of you claim to understand and oppose the ongoing harms of SARS-CoV-2, but continue to participate in, and normalise, environments and events that fuel its spread.

Participation legitimises the harm, does it not?
Attending an indoor concert (masked) still contributes money, attendance numbers & social legitimacy to an event that has zero protections in place, resulting in multiple new infections. Low paid staff at these events are put in harms way.

By participating, you’re endorsing it.
Read 10 tweets
Jul 5
Covid damages the part of your brain (frontal lobe) which is responsible for empathy, emotional regulation & overcoming self-centeredness.

This will facilitate immorality.

Each & every infection you have causes damage.

Many are on infection 4 (or more).

Signed, a neurologist.
Unless you’re taking measures to prevent infection, you’re catching SARS-CoV-2 frequently. Many infections are asymptomatic.

Each new infection will compound the brain damage, causing new issues that previous infections may not have done.

You are gambling with your cognition. Image
Image
Image
Image
Due to the nature of the aforementioned brain damage, many who succumb to such damage are completely unaware of the fact.

It is, in fact, quite common to be unaware of your brain damage, even in severe cases.

The medical term for this is anosognosia.

Just a heads up. Image
Read 11 tweets
Apr 2
After targeted harassment & defamation, I’ve realised that people want to insist that doctors take all SARS-CoV-2 sequelae seriously, except for neurological sequelae/brain damage.

I’ve been called ableist & bigoted for stating that damage can negatively affect behaviour.

🧵
Suggesting that an increase in violent behaviour, diminishing empathy, increasing apathy & emotional lability, decreasing risk aversion & more disinhibition could be a result of damage to the frontal & temporal lobes in the brain is apparently ableist & bigoted.

Yet it is fact.
Many accusations come from those who have neurological disorders or brain damage themselves, presumably because they see it as an attack on them, that I’m somehow making the insinuation that any/all brain damage makes someone behave in an undesirable manner.

I am not saying this
Read 8 tweets
Mar 31
Lol.

Most people keep getting sick w/a few months respite between infections (Covid, flu, norovirus, take your pick).

What in gods name do people think Long Covid is?

“Yeah I get sick all the time since I had Covid & I’ve had that several times. But I don’t have long covid” 😂
My dude, that’s Long Covid.

“Erm no it’s not. I just keep getting sick”.

And what does it mean if you keep getting sick?

“Erm that my immune system isn’t working properly… [long thoughtful pause]”

Immune system damage sounds like Long Covid to me.

“You could be right”

I am
Here’s the long & short of it. If something has changed regarding your health since Covid arrived on the scene, the overwhelming chances are that it’s Long Covid.

Whether that’s getting sick more often, new fatigue, diabetes, cognitive issues, insomnia, or all of the above.
Read 9 tweets
Mar 11
In neurology/psychiatry, we would call this Apathy.

Brain damage to the frontal lobe (dorsal anterior cingulate cortex) causes apathy & reduces empathy.

SARS-CoV-2 damages this region of the brain. Every. Single. Time.

More infections = more damage = more apathy.

🧵
Increase in apathy is often seen in traumatic brain injury, stroke & dementia.

It manifests as a lack of motivation/enthusiasm due to disruption in the brain regions responsible for goal directed behavior & reward processing.

Resulting in a lack of drive to engage in activities
Apathy means having a lack of interest in activities once enjoyed.

Difficulty in initiating tasks.

Reduced motivation to engage in social interactions.

Feeling indifferent & unbothered.

Everything the OP & others are experiencing, with many assuming they just have ‘burnout’.
Read 8 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(