Bryan Johnson Profile picture
Jul 21 4 tweets 2 min read Read on X
Weekly nightmares might predict premature death and speed up aging.

A study found that weekly nightmares made people 3x more likely to die prematurely (before the age of 75).

Here’s what they found and how to prevent premature death by nightmares. 🧵 Image
1/ The study is based on 4196 adults (age 26-74, 18-years of follow-up). Beyond increasing risk of premature death before 75, the findings showed that weekly nightmares accelerated aging, based on 3 epigenetic clocks:
+ Speed of aging (DunedinPACE)
+ Time until death prediction (GrimAge)
+ How old your body behaves physiologically (PhenoAge)

Nightmares are scary for your health.

They cause nocturnal stress on your body:
+ Resting heart rate jumps by up to 10bpm
+ Heart rate variability falls (bad for recovery)
+ Cortisol spikes, sympathetic activation, and accelerated breathing

Nightmares are more common during periods of high stress, in those with anxiety disorders, and in anyone with trauma‐related conditions like PTSD.
2/ Reduce nightmare frequency by treating root causes and following a good sleep protocol. Image
3/ Treat root causes:
+ address anxiety or PTSD with psychotherapies
+ conduct a thorough review of meds with nightmares as a side-effect

Imagery Rehearsal Therapy (IRT) is a targeted psychotherapy that flips the nightmare script to consciously reimagine and replace it with a new dream, during the day. It has moderate effects comparable to medication (Prazosin) in smaller cohorts.Image

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More from @bryan_johnson

Jul 2
PFAS are forever chemicals.
In cookware, floss, and fast food wrappers.
They hurt fertility, the brain, and immune system.

They accumulate and the body can't eliminate them.
I got my levels tested.

Here’s what you can do to avoid your exposure. 🧵 Image
0/ PFAS are a class of 12,000+ man-made chemicals used to make things water-, stain-, and heat-resistant.

They’re found in:
+ nonstick pans
+ waterproof clothing
+ fast food wrappers
+ microwave popcorn bags
+ dental floss
1/ PFAS are linked to:

+ lower sperm count
+ disrupted thyroid hormones
+ immune suppression
+ elevated cholesterol
+ liver damage
+ increased cancer risk (kidney, testicular)
+ neurodevelopmental issues
+ lower fertility in women

This isn’t hyperbole, it’s supported by strong epidemiological data. Dozens of studies backed by the CDC, EPA, and NIH, support these findings.
Read 6 tweets
Jun 24
Glass had 5 – 50× higher plastic than plastic or cans

The French tested water, soda, beer, iced tea, lemonade, and wine sold nationwide and found that glass-bottled beverages carried far more plastic shrapnel than plastic bottles or cans.
🧵Image
0/ What the study found

“Around a hundred microplastic particles per litre” in cola, lemonade, iced tea and beer packed in glass — 5 – 50 × higher than their plastic-bottled or canned twins.

For still or sparkling water the counts were lower but still lopsided: 4.5 µplastics /L in glass vs. 1.6 µplastics /L in plastic.

Wine (with a cork, not a crown cap) stayed almost micro-plastic-free.
1/ Why is glass worse?

Paint flakes from the metal crown caps are almost identical in colour and polymer chemistry to the particles in the drink, pinning them as the culprit — not the glass itself.

Corked wine being microplastic free gives another strong clue

Cleaning matters: bottles capped with untreated crowns shed 287 particles /L, but a simple air-blast plus alcohol rinse cut that to 87 particles /L.
Read 8 tweets
Jun 18
15 sessions of sauna dramatically reduced toxins in my body.

+ 65% drop in 2,4-D
+ 100% drop in MEP
+ 15% drop in MBP
+ 100% drop in MEHP (undetectable post sauna)
+ 56% drop in NAPR
+ 56% drop in HEMA
+ 100% drop in Perchlorate (undetectable post sauna)

After completing fifteen sauna sessions, each lasting 20 minutes at 200°F, led to a significant reduction in my environmental toxins, three went from being abnormally high to undetectable post sauna.
0/ Baseline: toxin levels showed one high exposure and six moderate exposures. Approximately one month prior to starting the sauna regimen, urine tests indicated one high exposure (levels exceeding the 95th percentile), and six moderate exposures ( levels between the 75th and 95th percentiles).

Post-sauna: high exposures completely eliminated, only one medium exposure remained, and three previous moderate exposures became undetectable.
Here are toxins that sauna helped me eliminate from my body, and why it matters

1/ 2,4-Dichlorophenoxyacetic Acid (2,4-D)

High exposure → lower medium exposure

2,4-D is a herbicide, so it is probably leaking into my food via some fresh produce, which is very hard to monitor due to batch variation. I have been testing periodically and will continue to do so.
Read 7 tweets
May 22
Allulose is perhaps the most longevity-friendly sweetener. 🧵

Here's why:
+ it's safe
+ multiple health benefits
+ reduced blood glucose
+ metabolic benefits including fat loss, increased GLP1 secretion, liver health, teeth protection. Image
0/ What is Allulose?
Allulose is a rare sugar found naturally in fruits like figs and raisins. It is nearly calorie-free (0.2-0.4 kcal/g) because it is absorbed and excreted through urine without being metabolized by the human body. The minimal calorie contribution is attributed to limited metabolism by gut bacteria.
1/ Safety of allulose

Concerns regarding allulose mainly revolve around potential gastrointestinal issues, including severe diarrhea. However, a clinical study involving 30 adults (15 women and 15 men aged 21-30) determined that allulose was well-tolerated without digestive problems at single doses up to 0.4 g/kg and daily intakes of 0.9 g/kg of body weight. For a 70 kg adult, this equates to a single dose of 28 grams and a daily intake of 63 grams. Ref

The FDA also recognizes allulose as a low-calorie sweetener and excludes it from the definition of added sugars due to its non-metabolizable nature in the human body. RefImage
Read 7 tweets
May 20
First, I shocked my Johnson and performance improved.
Then I shocked my sprained ankle and recovered faster.
Now, I’m shocking my entire body…
🧵
0/ This technology (@SoftwaveTRT) delivers unfocused electro-hydraulic shock waves dispersed over a broad tissue volume. The acoustic pulse passes non-invasively through skin, generating shear forces and micro-cavitation that set off mechanotransduction. Cells release ATP, open stretch-activated ion channels and trigger ERK/Akt signaling.

Within 30 minutes to 24 hours, endothelial-NO synthase and VEGF rise, micro-perfusion improves, and mesenchymal stem cells migrate to the site over subsequent days. End result: increased blood flow, pro-healing growth-factor signaling and activated resident stem-cell repair machinery.

Clinical trials show strong pain relief and faster healing for plantar-fasciitis heels, calcified shoulder tendons and improved blood flow for erectile dysfunction; decent evidence for tennis elbow,Achilles issues and chronic wounds; early data for nerve pain and chronic wounds.
1/ My team and I found this technology when we were working on Rejuvenating Johnson’s Johnson. We all want youthful brains and hearts and sexual function.

There are multiple randomized controlled trials showing shockwave therapy improves erectile dysfunction. Given that my sexual function was normal, we wanted to test whether it could further enhance it as measured by total time nighttime erections, subjective sexual performance, sexual satisfaction, and medical imaging-based penile markers.

x.com/bryan_johnson/…
Read 5 tweets
May 7
Is sauna worth the hype?

There's evidence that sauna is a potential detox and longevity intervention with benefits to heart, metabolism, brain health, and skin. We’re going to put it to the test.

Here’s what you need to know…🧵 Image
0/ How it works…

Heat exposure in a sauna puts your body under mild stress, triggering natural repair processes that improve overall health. Finnish dry saunas specifically use controlled heat to stimulate these beneficial responses, including:

+ Repairing and maintaining proteins (heat shock proteins)
+ Improving blood flow and relaxing blood vessels
+ Boosting antioxidant activity
+ Optimizing metabolism
+ Enhancing fitness
+ Reducing inflammation
+ Strengthening immunity
+ Recycling and repairing cells (autophagy)

All these processes combine to give whole-body health benefits.Image
1/ It protects your heart…

Regular sauna use (4–7 times a week, sessions lasting at least 19 minutes) can significantly improve heart health and lower blood pressure. Research shows the more often you sauna, the greater your protection from heart disease:

Heart disease risk:
2–3 times/week → 23% lower risk
4–7 times/week → 48% lower risk

High blood pressure risk (in healthy men aged 42–60):
2–3 times/week → 17% lower risk
4–7 times/week → 47% lower risk

In patients with existing heart failure, using a sauna 5 times a week for 3 weeks improved heart function by nearly 7%, lowered stress hormones by 25%, and reduced heart failure markers by over 20%. Longer and more frequent sauna sessions offer the strongest protection.Image
Read 11 tweets

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