Dalton (Analyze & Optimize) Profile picture
Jul 22, 2025 • 11 tweets • 5 min read • Read on X
A new study has shown that a simple, cheap over the counter supplement can have regenerative & life saving benefits for the brain in one week.

(🧵1/8)Image
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This study gave people with physical damage to the brain (traumatic brain injury or TBI):

āžœ A single dose of 4 g of N-acetylcysteine (NAC)
āžœ Then 2 g every 12 hours for 4 days
āžœ Then 1.5 g every 12 h for 3 days

on top of standard TBI treatment.

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Though the NAC group was similar overall to the placebo group (who only received standard TBI treatment),

more people in the NAC group (75%) had severe brain injury in comparison to the control (55%) at the beginning of the study.

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NAC improved metrics of inflammation and damage across the board:

ā˜† Reduced IL-6 (inflammatory cytokine)
ā˜† Improved MDA (marker of oxidative damage)
ā˜† Lower NSE + S100B (intracellular proteins that get released when brain cells die)

again, all within one week. (4/8) Image
NAC didn't just improve blood markers - it improved real outcomes too.

People on NAC improved by over 53% on the GCS - a measure of cognitive function following brain injury.

Those on standard therapy alone? Just under 13%.

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People taking NAC also spent significantly less time in the hospital,

on average getting out of the ICU about a week in advance.

Another sign that the NAC is working quickly to help repair the brain.

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NAC improved survival from brain injury.

10% of people died after 28 days who used just one week of NAC.

30% of people without NAC died over that same time period.

Remember, more people had severe TBI in the NAC group as well - making these results even more impressive.

(7/8) Image
Traumatic brain injury causes the release of damaged cell parts, which triggers inflammation, which then increases oxidative stress.

These processes further worsen brain damage, mitochondrial function and cognition.

NAC works in multiple different ways to protect the brain from this type of injury.

1. Prevents excessive oxidative stress from damaging cell components (by being a glutathione precursor)
2. Prevents oxidative stress from disrupting mitochondrial function - which supplies neurons with necessary energy to survive and thrive
3. Inhibits the activation of microglia - inflammatory cells of the brain
4. Prevents excessive glutamate release - which can trigger excitotoxicity in neurons

All of this prevents cell damage, death and energetic deficiency, which allows cells to stay alive and continue the healing process.

(8/8)Image
Read the full study here:
pmc.ncbi.nlm.nih.gov/articles/PMC12…
Even if you don't have TBI, NAC has multiple protective effects for the brain, including mental health:
If you're interested in getting personalized help on targeted supplementation, nutrition and lifestyle to suit your health goals, schedule a free call with us here: go.prism.miami/consultation

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More from @Outdoctrination

Feb 13
There's a 94% chance you're low on this vitamin.

It impacts nearly every disease and aging process imaginable.

VITAMIN E is one of the most multifaceted tools to maintain your health.

Here's why (🧵1/15):Image
Vitamin E does a few things that make it so powerful:

1. Prevents the destruction of polyunsaturated fats (think seed oil)
2. Lowers inflammation (from these fats)
3. Counteracts estrogen

These 3 processes alone are involved for the vast majority of health issues.
The breakdown of polyunsaturated fats is a fundamental driver of aging and deterioration.

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Vitamin E is the body's natural way of preventing this as it sits in our cell membranes and actively stops the chain reaction.Image
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Feb 12
Iron can actually SHORTEN your lifespan and age you on a cellular level.

(🧵1/10)Image
This study was published in 2024, investigating the effects of iron chelation on age related parameters.

They used a common aging animal model - a Klotho knockout animal.

Animals are known to have shorter lifespans without this gene, and longer lifespans with more of it.

They gave them a drug called deferiprone, which binds up free iron and gets rid of it.Image
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Well it's main function is a co-receptor for FGF proteins, which govern various metabolic functions (fat burning, glucose uptake, etc.) as well as vitamin D synthesis.

But it also shows a number of other anti-aging effects:

ā—ˆ Reduced oxidative stress
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Read 11 tweets
Feb 12
Put your finger on your wrist like this right now.

I can tell you more about your health on this alone than with $100s in lab tests.

Ready? This is what it means (🧵1/8):Image
What you are feeling is your radial artery in your wrist area.

This tells you your:

ā—‡ Heart rate (duh)
ā—‡ Pulse amplitude

Both of these give you a ton of information on your health - in real time.

Let's talk about your heart rate first Image
A LOW heart rate is often associated with hypothyroidism.

This is not always true, for instance athletes have lower pulse rates due to adaptation,

but in many people, a low HR indicates thyroid function.

A few functional thyroid doctors like to see this number at 70-85 BPM, and that pretty much aligns with our experience with our clients.Image
Read 8 tweets
Feb 10
Aged garlic was shown to shrink arterial plaques in a landmark clinical trial.

(🧵1/7)Image
Image
This study was published in 2019, examining people with diabetes with plaque in the coronary artery.

This is the primary place where if plaque forms, you're susceptible to a heart attack. Image
They also used what is now considered the best tool for predicting heart disease - Coronary Computed Tomography Angiography (CCTA).

This is an imaging technique used to visualize the plaques.

For this reason, it's incredibly accurate at seeing active disease. Image
Read 8 tweets
Feb 8
N-acetylcysteine (NAC) was shown to reverse brain damage from aluminum in a critical study.

(🧵1/8)Image
Animals were put into 6 groups - either getting aluminum or NAC or both.

The aluminum was administered as aluminum chloride, and it was done so orally.

This is important because roughly only 0.5% of oral aluminum chloride is absorbed, so the real effective doses the animals received were far less than than the 100 mg / kg.

This is still a high dose, but aluminum is known to accumulate in tissues.Image
Animals had severely impaired memory performance with the aluminum, but this was improved with NAC.

The morris water test trains rats to find a hidden platform in pool.

The latencies (times) is how long it takes to find it on a given day.

Less time = better memory.

As you can see, the high dose NAC almost completely reversed the memory impairment from aluminum.Image
Read 11 tweets
Feb 5
Vinegar drastically reduces blood sugar and insulin levels, according to multiple clinical trials.

(🧵1/7)Image
This first paper is a review article from 2017.

They looked at studies giving people vinegar alongside meals and monitored their blood sugar and insulin responses.

Having high levels of these post meal is highly indicative of insulin resistance and is a risk for heart disease.

Apologies, I do not have the official PDF so I'm working with the raw file here.Image
Here were the included studies.

Most are looking at roughly one tablespoon of vinegar alongside a meal with carbs. Image
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Read 10 tweets

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