Dr Elisa Perego Profile picture
Jul 23 7 tweets 3 min read Read on X
There are concerns about a "mysterious illness" going through the pelaton at the top cycling event Tour de France. Several racers were reported to be affected already days ago. Since then, star M. van der Poel has withdrawn with pneumonia while R. Evenepoel left feeling "empty" Image
One of the most prominent racers affected by the "mysterious illness" was superstar and current Tour leader Tadej Pogačar, who lamented cold symptoms but remains in the race. Van der Poel also had cold symptoms, which has now progressed to pneumonia

rmcsport.bfmtv.com/cyclisme/tour-…
Tadej Pogačar told reporters on Sunday "Am I sick? Thanks for checking in, actually I'm better, it's almost over" He added: "I have a bit of a runny nose, a bit of a cough, but I'm not really sick. It's just a bit of a pain in the *ss."
Pogačar currently remains Tour leader
Others have been in worse shape. Star M. van der Poel said he felt weakened last Sunday. "How am I feeling after this cold? Not great. I'm not recovering well," he lamented at the start in Muret. He raced but later had to be taken to the hospital and was diagnosed with pneumonia
Steff Cras, the Belgian leader of TotalEnergies, left the Tour de France in tears on the first slopes of the Col du Tourmalet. "Our Belgian climber Steff Cras, who was ill at the start this morning, has been forced to abandon the 14th stage of the Tour de France," his team said.
A few minutes later, star Remco Evenepoel also left the race, feeling "empty" and concerned about the rest of the season. Remco, who was leader of the white jersey and 3rd overall, had felt not ok for 3 days in a row (it remains unclear if he had a virus)

cyclingnews.com/news/it-just-w…
"Tobias Johannessen (Uno-X Mobility) was given oxygen at the summit of the Mont Ventoux and taken to hospital after a gruelling Stage 16 of the Tour." He suffered from abdominal pain. He is reported to feel better and maintained his 8th overall position

tntsports.co.uk/cycling/tour-d…

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More from @elisaperego78

May 20
Five years ago today the term #LongCovid was first used as a Twitter hashtag. A single tweet by a patient linked together a growing, grassroots movement of people who weren't recovering from Covid. Across the world, we were fighting for recognition and studying our own disease Image
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I feel strange posting this again after five years of fighting, suffering, and a global, grassroot mobilization of Covid survivors, who changed how Covid was understood and communicated to the public
Far from being a short, respiratory illness in most, dangerous only for the "old and frail", as said in early guidelines, Covid was a prolonged, multi-system disease, which could be severe and even fatal also in the "young and healthy": #LongCovid

sciencedirect.com/science/articl…
Read 20 tweets
May 19
A severe surge in Covid cases is reported in Asian countries.
"In Hong Kong, weekly cases surged over 30 times in 10 weeks. Cases also surged by nearly 30 per cent in a week in Singapore. There are also reports of significant surges in China and Thailand"
indiatoday.in/diu/story/in-n…
There also seems to be a raise in certain indicators about Covid in Italy, such as child hospitalizations, in Italy, where novel variants of concern have been detected
However, surveillance in the country remains low

Italy PM Giorgia Meloni would be suffering from a "fever" and has cancelled institutional meetings

Read 4 tweets
May 11
Biopsies of five patients with myocarditis in #LongCovid showed disruption of mitochondrial integrity in the heart. This research was replicated in mice and shed light on the profound cardiovascular impact of SARS-CoV-2 infection on cardiovascular health
sciencedirect.com/science/articl…
The team's "investigation provides histopathological and electron microscopic analyses from endomyocardial biopsies of five patients who experienced various post-COVID-19 cardiovascular outcomes." such as myocarditis (inflammation of the heart muscle)
"Electron microscopy revealed widespread mitochondrial disorder and the presence of myofilament degradation within the cardiomyocytes from the patients.

Similar mitochondria disorganization were found in SARS-CoV-2 infected mice."
Read 5 tweets
May 10
I appreciate WHO raising awareness about Long Covid. I, however, considered, and still consider, a great mistake to have declared the end of Covid "as a global emergency" two years ago. This contributed to minimize the ongoing risks of SARS-CoV-2 infection, including death and LC
We must also interrogate ourselves as to whether LC is (only) 6% of people who get Covid (as per WHO quote). I think further reflection is needed here, especially when taking into consideration sub-clinical pathology and those who are never diagnosed with LC.
(Not making any assumptions about prevalence and incidence of LC in this thread myself, as there are so many issues to consider, as I have already pointed out many times. I think, however, health bodies should be careful around this point, too.)
Read 4 tweets
May 7
New PET imaging data reveal the long-term impact of COVID on heart and lungs, showing changes to these organs which are not detectable by standard medical assessments. 

#LongCovid

healthimaging.com/topics/medical…
"We [study's authors] believe long COVID results in an inflammatory response that may predispose patients to premature coronary artery disease, pulmonary hypertension, and valvular damage such as stenosis or regurgitation."
Study on 100 patients who were treated for COVID in 🇺🇸 between December 2020 and July 2021. Nearly one year after their initial infection, each patient was struggling with lingering cardiopulmonary symptoms; 91 underwent hybrid 18F-fluorodeoxyglucose PET/MRI
Read 8 tweets
May 5
NVC test shows significant microvascular damage in #LongCovid patients vs matched healthy controls. Dilated capillaries, microhaemorrhages, abnormal shapes and reduced capillary density are still detectable in LC 12 months after acute SARS-CoV-2 infection
rmdopen.bmj.com/content/11/2/e…
Background to the study "SARS-CoV-2 induces endothelial and capillary damage, that is detectable by nailfold videocapillaroscopy (NVC)."
"NVC [had showed in prior research] significant capillary dilations, microhaemorrhages and abnormal shapes in the acute phase of COVID-19 and significant reduction of nailfold capillary density in the short-term recovery phase (3 months)."
Read 4 tweets

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