Cervical cancer is being defeated thanks to two things:
Pap smears and the Gardasil vaccine.
HPV vaccination is so effective that many countries will have practically eliminated cervical cancer in the next two decades.
Here's why🧵
Cervical cancer develops from HPV because the HP virus integrates itself into cells' DNA and then degrades proteins that keep cell growth in check, leading to precancerous growths and then cancer.
This man received a Nobel Prize for that discovery:
The HPV vaccine stops this precursor to cervical cancer in its tracks.
Its effects on the most common types of precancerous growths (HPV16/18—about 70% of all cervical cancers) are near-total prevention.
The White House just released a really good executive order on cleaning up America's streets, re-institutionalizing insane people, and ending open air drug abuse and the problems it creates.
Here's a quick overview🧵
The first section is the one I'm most excited for. An alternative name for it could be "Bring Back The Asylums"
It instructs the administration to make it possible to involuntarily commit crazy people again
That crazy hobo pushing a cart full of urine bottles? He's going away!
The next section is one that you'll need to familiarize yourself with if you're interested in 'what happens next'.
This was a never achieved goal in Trump-I.
The idea is to compel cities to do what you want by withholding, barring, and giving discretionary funds for compliance.
What comes after myostatin inhibitors make everyone buff?
One new candidate is:
Safe, cheap, and easily-administered injections that locally remove fat. A new drug that just passed through phase 2 seems to do just that🧵
The new drug is called CBL-514.
It has a counterpart on the market in the form of deoxycholic acid injections—brand name Kybella.
Kybella is FDA-approved, and it works: it helps people to get rid of their double chins. But there's a catch.
Kybella, unfortunately, is not all that safe, and though many patients swear by it, there are notable side effects.
This is predictable, since the way Kybella works is through cytolysis: causing cells to die by rupturing them, releasing their contents, causing inflammation.
Pseudonyms afforded the protection needed to write things that were controversial, to engender debate over things they didn't themselves believe in, and to encourage focus on ideas over reputations
Thread of their known pseudonyms🧵
Alexander Hamilton, James Madison, and John Jay all wrote under the name Publius, after the Roman consul Publius Valerius Poplicola.
This shared authorship became known after Hamilton died, but the individual authors of the Federalist Papers Publius entries remain debated.
John Jay and John Stevens, Jr. shared the Americanus pseudonym when writing various Federalist essays.