Dr.Sayajirao Gaikwad Profile picture
Aug 2 14 tweets 3 min read Read on X
💩 Poop is one of the most powerful biomarkers in medicine but also the most ignored.

Each bowel movement reveals data on gut health, nutrient absorption, liver & pancreas function, inflammation, and immunity.
Here’s a scientific breakdown worth saving 🧵👇
#GutHealth
1️⃣ What exactly is poop made of?
On average:
🔸~75% water
🔸~25% solids

Of the solids:
🔸30% dead & living bacteria
🔸30% indigestible fiber
🔸10–20% fat
🔸10–20% inorganic matter
🔸Small amounts of protein, dead cells, bile pigments

This is microbial data, not just waste.
2️⃣ Color: A reflection of bile + liver function
🟤 Brown = Normal (from bile + bilirubin)
🟢 Green = Rapid transit, magnesium, leafy greens
⚫ Black = Upper GI bleeding, iron supplements
🔴 Red = Lower GI bleeding, hemorrhoids, fissures
🟡 Pale/Clay = Bile obstruction check liver
⚪ White = No bile. serious warning sign
3️⃣ Consistency: Bristol Stool Chart
This globally used tool categorizes stool into 7 types:
Type 1-2: Hard, dry, slow transit → constipation

Type 3-4: Soft, smooth, sausage-shaped → ideal

Type 5-7: Loose, fast transit → malabsorption, IBS, infection

Best gut health = Type 3 or 4, once or twice daily.
4️⃣ Floating stool = Fat malabsorption
Fat should be absorbed in the small intestine.
If stool floats, sticks to the bowl, or looks greasy:

🧪 Check for:
•Low bile output
•Pancreatic insufficiency
•Celiac disease
•SIBO
•Liver/gallbladder dysfunction
5️⃣ Mucus, undigested food, or smell?
Mucus = Inflammation in colon (IBD, colitis, infections)

Undigested food = Fast transit, low enzymes, poor chewing

Strong foul odor = Protein putrefaction, dysbiosis, malabsorption

Gut should ferment fiber, not rot protein.
6️⃣ Transit time = Gut speed + microbiome function
⏱️ Normal: 18–24 hours
📌 Try the Beet Test: Eat beetroot and track red color in stool
<12 hrs = fast transit, possible poor absorption

36 hrs = constipation, stagnation

Long transit = toxin reabsorption
Short = nutrient loss
7️⃣ Chronic constipation: Not just lack of fiber
Often due to:
•Hypothyroidism
•Magnesium deficiency
•Low water intake
•Low bile or sluggish liver
•Sedentary lifestyle
•Gut microbiome imbalance

💡 Over-supplementing insoluble fiber can worsen it.
8️⃣ Diarrhea = Not always infection
Could be:
Bile acid diarrhea
Lactose/FODMAP intolerance
SIBO
IBD flare
Excess magnesium or vitamin C
Gut-brain axis stress response

Test, don’t guess.
9️⃣ Stool and mental health are connected
💡 90% of serotonin is made in the gut
💩 Poor stool quality is often seen with:
•Anxiety
•Depression
•Brain fog
•Insomnia

Psychobiotics (targeted probiotics) may improve mood via gut-brain axis.
🔟 One of the most ignored signs: Pale stool
A pale, clay-colored stool = no bile entering the intestine
May indicate:
•Bile duct blockage
•Liver cirrhosis
•Gallstones
•Tumor (rare)

NEVER ignore this. Needs immediate medical evaluation.
1️⃣1️⃣ What ideal poop looks like
✔️ 1–2 times/day
✔️ Type 3–4
✔️ Medium brown
✔️ No undigested food
✔️ No mucus or blood
✔️ Easy to pass, single wipe
✔️ Sinks slowly

Anything else = time to investigate digestion and absorption.
1️⃣2️⃣ How to improve poop quality?
science-backed tips:
✅ Prioritize gut repair: remove inflammatory foods
✅ Include prebiotics + fermented foods
✅ Optimize magnesium and hydration
✅ Focus on chewing and mindful eating
✅ Ensure bile flow: healthy fats, bitters
✅ Get daily movement
📌 Poop is more than waste.
It’s data.
It’s diagnostics.
It’s daily feedback from the microbiome, liver, and gut.

Ignore it and you miss early warning signs.
💾 Save this thread.
🔁 Share it with someone who needs to look in the toilet, not just the lab.
💬 Questions or symptoms? Let’s talk in replies.

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More from @DietDrsayajirao

Jul 31
Leptin: The Master Fat-Burning Hormone You’ve Never Heard Enough About

Struggling with weight loss even while eating less?
Always hungry even after meals?
The problem may not be willpower it may be Leptin Resistance.
Let’s dive deep 🧵 👇
#Obesity #Diabetes
What is Leptin?

Leptin is a hormone made by fat cells (adipocytes).
Its job is simple but powerful:

✅ Tells your brain: “You have enough energy stop eating.”
✅ Boosts metabolism
✅ Helps regulate fertility, immunity, and thyroid function

It’s often called the “satiety hormone” or “anti-starvation signal.”
How does Leptin work?

Leptin travels from fat tissue → to the brain (hypothalamus) and says:

🧠 “Energy levels are good. Reduce hunger. Burn more fat.”

So, more fat = more leptin = less hunger… in theory.

But in many people, the system breaks.

Enter: Leptin Resistance
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Jul 29
🫀 Key Cardiac Risk Markers You Shouldn’t Ignore
Heart attacks in 20s & 30s are becoming frighteningly common.
Fit on the outside ≠ Healthy on the inside.
Here’s how to investigate early & prevent silent cardiac risk 🧵 👇
🔴 1. Lipid Profile is just the beginning
Check more than just total cholesterol.
✅ LDL (bad cholesterol)
✅ HDL (good cholesterol)
✅ Triglycerides (TG)
✅ VLDL

🔍 Ideal:
•TG < 100
•HDL > 50
•LDL < 100
•TG/HDL ratio < 2
🔴 2. ApoB & ApoA1 – Better than LDL
🔸ApoB = Number of artery-clogging particles
🔸ApoA1 = Protective particles

✅ Ideal ApoB < 90
✅ ApoB/ApoA1 Ratio < 0.6
This is a stronger predictor of heart disease than LDL alone.
Read 9 tweets
Jul 28
How many calories do you actually need in a day?
Don’t guess.
Learn how to calculate your Total Energy Expenditure (TEE) in 30 seconds.
1️⃣ Step 1: Calculate BMR (Basal Metabolic Rate)

Use the Mifflin-St Jeor formula:

👨‍🦱 For men:
BMR = 10 × weight(kg) + 6.25 × height(cm) – 5 × age + 5

👩‍🦰 For women:
BMR = 10 × weight + 6.25 × height – 5 × age – 161

This gives you the calories your body burns at rest.
2️⃣ Step 2: Multiply BMR by your activity level:

🔹 Sedentary (no exercise): ×1.2
🔹 Lightly active (1–3x/week): ×1.375
🔹 Moderately active (3–5x/week): ×1.55
🔹 Very active (6–7x/week): ×1.725
🔹 Super active (physical job + intense training): ×1.9

📌 Example:

Male | 35 yrs | 93 kg | 183 cm | Moderate activity
BMR = ~1900 kcal
TEE = 1900 × 1.55 = ~2950 kcal/day

This is the number of calories to maintain current weight.
Read 4 tweets
Jul 28
Why I Chose a Protein Priority Diet: 10 Life-Changing Reasons
If you’ve been struggling with fat loss, low energy, or poor health
Read this till the end.
This one dietary shift changed everything for me 🧵👇
1️⃣ I wanted to lose fat, not muscle.
Most diets make you lose weight fast but it’s often muscle, not fat.
Protein helped me preserve lean mass while cutting fat.
And more muscle = better metabolism, better health.
2️⃣ I was tired of feeling hungry all the time.
Protein is the most filling macronutrient.
I started eating more eggs, paneer, curd, chicken, dals… and stopped thinking about food every 2 hours.
Hunger became manageable. Cravings dropped.
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Jul 26
Just diagnosed with Pre-Diabetes?
Here’s exactly what I would do to reverse it without meds step-by-step.
No panic. No pills. Just food, muscle, and discipline.
This is how I’d take back control of my health,backed by science 🧵
#Prediabetes #DiabetesReversal #InsulinResistance
1️⃣ First, understand what pre-diabetes really means.

It’s not “mild diabetes.”
It’s a red flag 🚩

It means:
📉 Insulin is rising
📈 Sugar is rising
⚠️ Fat is building in liver & belly
🧠 Risk of heart disease, stroke & type 2 diabetes has begun

It’s reversible.If I act now.
2️⃣ I’ll get a full metabolic health blood panel done:

Not just sugar, but the full picture:

🧪 Fasting glucose
🧪 Fasting insulin
🧪 HbA1c
🧪 Triglycerides, HDL
🧪 HOMA-IR (insulin resistance score)
🧪 hs-CRP (inflammation)
🧪 Vitamin D, B12, Ferritin, Magnesium

I’ll repeat these every 3–6 months to track reversal.
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How to follow a High-Protein Low-Carb VEGETARIAN diet in Shravan (without eggs)
Want to hit 1g protein/kg body weight even during this sacred month?
No onion, no garlic, no eggs. Still powerful. 🧵 👇
🥣 Breakfast Options (15–20g protein)
✅ 200g Paneer Tikki + salad
✅ Besan + Lauki Chilla + Peanut chutney
✅ Tofu stir-fry + cucumber + 30g nuts/seeds

🧠 Start your day with protein, not cereal or poha.
🍛 Lunch Options (20–25g protein)
✅ 200ml Moong dal + 150g Paneer sabzi
✅ Besan thepla + curd + coconut chutney
✅ Rajma-Lauki curry + curd + salad (non-fasting)

Protein + fiber = Satiety + Weight Loss
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