James Throt MBBS, MD, PhD, FRCPath Profile picture
Aug 8 14 tweets 5 min read Read on X
Surging aggression. Language delays. Dysregulation. Developmental issues. Teachers & parents are seeing major changes in children.

Lockdowns are often blamed. But UK lockdowns were short. So what else changed in early childhood since 2020?

Let’s talk about COVID. And brains. 🧵 Image
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Let’s be clear: lockdowns may have had an impact on some children, especially in unsafe homes or w/poor digital access. That shouldn’t be denied.

But what we’re seeing now goes far beyond what short-term isolation would explain, especially in children born after lockdowns ended.
Babies aren’t socialised in their first 2–3 months to protect their fragile immune systems. Instead, they focus on bonding with caregivers.

So blaming lockdowns for behavioral issues in babies born during or after 2020 ignores the major factor: widespread infections in infancy. Image
Since 2020, UK children (incl infants) have been repeatedly infected with SARS-CoV-2:

- A virus that enters the brain
- Damages grey & white matter
- Shrinks the frontal cortex
- Alters neurological development

Even after mild or asymptomatic infections.
The frontal lobe governs:

- Impulse control
- Language acquisition
- Emotional regulation
- Social behaviour
- Attention & learning
- Empathy

Subtle damage during development can profoundly affect behaviour and cognition.
Teachers are reporting:

- More violence, even in reception and KS1
- Children hitting staff & peers
- Difficulty with attention & following instructions
- Emotional volatility
- Delays in speech, literacy, writing, and social development

This is systemic. And new.
UK lockdowns were short-lived:

- Nurseries & early years reopened June 2020
- All year groups returned to school in September 2020
- Under-5s faced few social restrictions

Yet the youngest cohorts, many born after lockdowns, are showing the most concerning outcomes.

Why? Image
Here’s what changed… mass infection became policy:

- No clean air in schools
- No real protections for staff or students
- No vaccines for under-5s
- Reinfections normalised, even encouraged to achieve “herd immunity”

COVID became routine for children.

That has consequences.
COVID is not just a respiratory virus.

It’s neuroinvasive. It can:

- Cross the blood-brain barrier
- Persist in neural tissue
- Trigger brain inflammation
- Shrink the frontal cortex
- Affect white matter, connectivity, cognition

Even in mild/asymptomatic illness.
Even children born after lockdowns ended, who missed the brunt of restrictions, are showing worrying developmental trends:

- Delayed speech
- Poor attention span
- Trouble with emotional regulation
- Language & learning gaps

Kids will have had 3–6 covid infections before age 6.
Meanwhile, children who lived through the peak pandemic years are now in classrooms, and teachers are reporting:

- Violent outbursts
- Severe attention issues
- Struggles with empathy, self-control, and literacy

This points to something deeper than just lockdowns.
Multiple studies show COVID-19 affects developing brains:

🧠 Infants born to infected mothers show altered brain structure
🧠 Children post-covid show cognitive delays and inflammation
🧠 Even mild cases leave long-term neurological footprints
🧠 Risk grows with each reinfection
In short:

UK children are being repeatedly infected, often within their most vulnerable developmental windows, by a virus that damages the brain.

We are normalising this. Ignoring it. Blaming everything but the virus itself.

That is a societal failure of staggering proportions
This thread isn’t about fear, it’s about recognition

Lockdowns had an impact, yes, but something else is driving this

We owe it to children to ask the hard questions. To protect them from repeat brain injury that may alter their development, and their futures, permanently

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More from @JamesThrot

Aug 10
How Covid brain damage fuels social & political chaos in UK & USA 🧵

The UK & US face unprecedented strain on healthcare & social trust

Political discourse often scapegoats immigrants/minorities, ignoring a major driver:

The pandemic’s lasting & ongoing neurological toll

1/11 Image
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SARS-CoV-2 is neurotropic; it infects brain tissue, especially the frontal cortex, critical for empathy, impulse control, and decision-making.

Research shows repeat infections cause cumulative cognitive impairments & damage.

This inevitably erodes social reasoning.

2/
This slow-burning health crisis increases absenteeism, reduces workforce productivity, and overloads healthcare systems, all without obvious cause for most.

When people can’t see the virus causing this strain, they look for simpler explanations.

3/ Image
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Read 11 tweets
Jul 30
🧵 Thread: Why don’t people take COVID seriously in Year 6 of the pandemic?

A virus that disables the immune system, damages the brain, heart, and vasculature.

And spreads like smoke.

Yet the world shrugs.

Why?

Because mass denial is doing what it always does.

1/18 Image
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When a threat is chronic, invisible, and socially inconvenient, people don’t rationally evaluate it, they emotionally suppress it.

Denial becomes a survival mechanism. Especially in societies offering zero support for caution, it’s easier to numb out than face reality.

2/
This denial is socially rewarded.

If you mask, you’re weird.

If you talk about COVID, you’re exhausting.

If you stay home sick, you’re overreacting.

People protect their comfort and status by mirroring the crowd, even if the crowd is sleepwalking off a cliff.

3/
Read 21 tweets
Jul 14
The following question has been on my mind. So to the covid cautious community, I ask:

If you know that the virus, SARS-CoV-2, is harmful, persistent and disabling, why do some of you still participate in systems, relationships, behaviours, and events that perpetuate its spread?
Many of you claim to understand and oppose the ongoing harms of SARS-CoV-2, but continue to participate in, and normalise, environments and events that fuel its spread.

Participation legitimises the harm, does it not?
Attending an indoor concert (masked) still contributes money, attendance numbers & social legitimacy to an event that has zero protections in place, resulting in multiple new infections. Low paid staff at these events are put in harms way.

By participating, you’re endorsing it.
Read 10 tweets
Jul 5
Covid damages the part of your brain (frontal lobe) which is responsible for empathy, emotional regulation & overcoming self-centeredness.

This will facilitate immorality.

Each & every infection you have causes damage.

Many are on infection 4 (or more).

Signed, a neurologist.
Unless you’re taking measures to prevent infection, you’re catching SARS-CoV-2 frequently. Many infections are asymptomatic.

Each new infection will compound the brain damage, causing new issues that previous infections may not have done.

You are gambling with your cognition. Image
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Due to the nature of the aforementioned brain damage, many who succumb to such damage are completely unaware of the fact.

It is, in fact, quite common to be unaware of your brain damage, even in severe cases.

The medical term for this is anosognosia.

Just a heads up. Image
Read 11 tweets
Apr 2
After targeted harassment & defamation, I’ve realised that people want to insist that doctors take all SARS-CoV-2 sequelae seriously, except for neurological sequelae/brain damage.

I’ve been called ableist & bigoted for stating that damage can negatively affect behaviour.

🧵
Suggesting that an increase in violent behaviour, diminishing empathy, increasing apathy & emotional lability, decreasing risk aversion & more disinhibition could be a result of damage to the frontal & temporal lobes in the brain is apparently ableist & bigoted.

Yet it is fact.
Many accusations come from those who have neurological disorders or brain damage themselves, presumably because they see it as an attack on them, that I’m somehow making the insinuation that any/all brain damage makes someone behave in an undesirable manner.

I am not saying this
Read 8 tweets
Mar 31
Lol.

Most people keep getting sick w/a few months respite between infections (Covid, flu, norovirus, take your pick).

What in gods name do people think Long Covid is?

“Yeah I get sick all the time since I had Covid & I’ve had that several times. But I don’t have long covid” 😂
My dude, that’s Long Covid.

“Erm no it’s not. I just keep getting sick”.

And what does it mean if you keep getting sick?

“Erm that my immune system isn’t working properly… [long thoughtful pause]”

Immune system damage sounds like Long Covid to me.

“You could be right”

I am
Here’s the long & short of it. If something has changed regarding your health since Covid arrived on the scene, the overwhelming chances are that it’s Long Covid.

Whether that’s getting sick more often, new fatigue, diabetes, cognitive issues, insomnia, or all of the above.
Read 9 tweets

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