James Throt MBBS, MD, PhD, FRCPath Profile picture
Aug 13, 2025 18 tweets 6 min read Read on X
Surging aggression. Language delays. Developmental issues. Teachers & parents report major changes in children

Lockdowns are often blamed. But many lockdowns were short (e.g. UK)

So what else changed in early childhood since 2020?

I’m a neurologist. Let's talk COVID & brains🧵
Let's be clear: lockdowns may have had an impact on some children, especially in unsafe homes or w/poor digital access. That shouldn't be denied.

But what we're seeing now goes far beyond what short-term isolation would explain, especially in children born after lockdowns ended.
Babies aren't socialised in their first 2-3 months to protect their fragile immune systems. Instead, they focus on bonding with caregivers.

So blaming lockdowns for behavioral issues in babies born during or after 2020 ignores the major factor: widespread infections in infancy. Image
Since 2020, UK children (incl infants) have been repeatedly infected with SARS-CoV-2:

- A virus that enters the brain
- Damages grey & white matter
- Shrinks the frontal cortex
- Alters neurological development

This is even after mild & asymptomatic infections.
The frontal lobe governs:

- Impulse control
- Language acquisition
- Emotional regulation
- Social behaviour
- Attention & learning
- Empathy

Subtle damage during development can profoundly affect behaviour and cognition.
Teachers are reporting:

- More violence, even in reception and Key Stage 1
- Children hitting staff & peers
- Difficulty with attention & following instructions
- Emotional volatility
- Delays in speech, literacy, writing, and social development

This is systemic. And new.
UK lockdowns were short-lived:

- Nurseries & early years reopened June 2020
- All year groups returned to school in September 2020
- Under-5s faced few social restrictions

Yet the youngest cohorts, many born after lockdowns, are showing the most concerning outcomes.

Why? Image
Here's what changed... mass infection became policy:

- No clean air in schools
- No real protections for staff or students
- No vaccines for under-5s
- Reinfections normalised, even encouraged to achieve "herd immunity"

COVID became routine for children.

That has consequences.
COVID is not just a respiratory virus.

It's neuroinvasive. It can:

- Cross the blood-brain barrier
- Persist in neural tissue
- Trigger brain inflammation
- Shrink the frontal cortex
- Affect white matter, connectivity, cognition

Even in mild /asymptomatic illness.
Even children born after lockdowns ended, who missed the brunt of restrictions, are showing worrying developmental trends:

- Delayed speech
- Poor attention span
- Trouble with emotional regulation
- Language & learning gaps

Kids will have had 3-6 covid infections before age 6.
Meanwhile, children who lived through the peak pandemic years are now in classrooms, and teachers are reporting:

- Violent outbursts
- Severe attention issues
- Struggles with empathy, self-control, and literacy

This points to something deeper than just lockdowns.
Multiple studies show COVID-19 affects developing brains:

🧠 Infants born to infected mothers show altered brain structure
🧠 Children post-covid show cognitive delays and inflammation
🧠 Even mild cases leave long-term neurological footprints
🧠 Risk grows with each reinfection Image
Image
In short:

UK children are being repeatedly infected, often within their most vulnerable developmental windows, by a virus that damages the brain.

We are normalising this. Ignoring it. Blaming everything but the virus itself.

That is a societal failure of staggering proportions
This thread isn't about fear, it's about recognition

Lockdowns had an impact, yes, but something else is driving this

We owe it to children to ask the hard questions

To protect them from repeat brain injury that may alter their development, and their futures, permanently

END Image
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It should come as no surprise that this situation ⬇️ is quickly deteriorating, having been reported on TODAY.

“Disturbing rise in domestic abuse among 16 to 25 year olds”

“Children as young as nine are asking about violent pornography and displaying misogynistic behaviour.”
I have no idea why Twitter/X decided to remove the images from the initial post in the thread, and instead write out a link for the tweet as a replacement.

But here is what was originally attached:
I would like to address today’s news that A-Level results have “risen again” and “top grades are up”, when this is in complete contradiction to the bulk of this thread.

My quoted thread below deals with this phenomenon and explains exactly what is going on here…
“Should be of concern to all of us”

Yet they turn a blind eye to the root cause of the problem.

These are our policymakers.

Frightening really.

(This is Canada, the problem is ubiquitous)

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More from @JamesThrot

Mar 18
Because COVID has caused so many health problems for so many people, they’re inundated with patients demanding help for their new ailments.

And because nobody, including doctors, wants to acknowledge COVID, it’s more convenient to label the myriad of health problems as “anxiety”
“My new issue that just so happened to appear post-2020 is nothing to do with COVID”

Maybe not.

But repeated infections w/a virus that is vasculotropic, neurotropic, cardiotropic, thromboembolic, oncogenic & damages the immune system certainly won’t be beneficial to your health
I increasingly suspect a feedback loop is emerging in medicine.

People develop health problems after SARS-CoV-2 infection, but neither the patient nor the doctor wants to raise COVID as a possible factor.

So it quietly disappears from the diagnostic conversation.
Read 11 tweets
Mar 15
Two students at the University of Kent in the UK have died following an outbreak of "invasive" meningitis.

A further 11 students are currently in hospital and reported to be seriously ill.

All normal on plague island during a never-ending SARS-CoV-2 pandemic. Image
Image
It’s worth knowing that COVID has been associated with T-cell exhaustion, lymphopenia, impaired interferon responses & persistent immune dysregulation.

When host immune regulation is altered, susceptibility/vulnerability to other infections, like meningitis, can increase.
Pathogens responsible for meningitis, like Neisseria meningitidis & Streptococcus pneumoniae, often take hold when immune defenses are impaired.

If SARS-CoV-2 can dysregulate immune function, the downstream effects on vulnerability to infections need acknowledging.
Read 7 tweets
Mar 8
Spreading a brain damaging virus on repeat for >6 years won’t be helping

And since nobody has an appetite for avoiding brain damage, there’s no end in sight

Pretending your 8th COVID infection is just another cold won’t protect you either

Actions & inactions have consequences
Frontal lobes refine behaviour. COVID damages them.

They regulate impulse control, empathy, moral reasoning & judgment.

Damaged lobes mean someone can remain articulate & knowledgeable while becoming reckless, cruel, suggestible & catastrophically bad at evaluating consequences
Executive function is also degraded.

Intelligence without executive function is dangerous. You can be sharp, knowledgeable, eloquent… and still impulsively destroy lives, misjudge catastrophes, or follow urges with zero moral compass.

The brain’s brakes & filters are gone.
Read 6 tweets
Mar 7
MAGA has gone full throttle at attempting to smear me and claim I am unequivocally incorrect in my suggestion Trump may have FTD

Exhibit A below ⬇️

These are not the words of a world leader with fully functioning frontal lobes

His internal filter is progressively diminishing Image
MAGA has been hanging off every word of a dementia patient. No matter how ridiculous or how unhinged it became. They followed. They regurgitated. They worshipped.

The baseline for what constitutes normal behaviour has continually shifted into increasingly preposterous territory.
Imagine having to reckon with the fact you were hoodwinked, beguiled & cajoled by a cognitively compromised senior citizen w/progressive brain atrophy. This won’t sit well.

Under normal circumstances this individual would be in a memory care facility.

But instead, they’re POTUS
Read 5 tweets
Mar 5
As a neurologist, I’ve dealt with Frontotemporal Dementia (FTD) patients for years

I often pondered how diabolical it would be if a world leader suffered the same fate

Now I’m seeing it play out in real time

Without impeachment, this will get darker than you could ever imagine
Frontotemporal dementia attacks the frontal lobes. The brain’s command center for judgment, empathy, impulse control, moral reasoning and long-term planning.

Imagine a world leader whose frontal lobes progressively fail, but no one intervenes.

Or worse, they cheer it on.
As FTD progresses, disinhibition dominates.

The leader may issue impulsive orders, make erratic public statements or flout norms & laws.

Even in those who were previously unmalicious, there would be a genuine neurological inability to foresee consequences.
Read 17 tweets
Mar 3
When you realise that frontal lobe dysfunction lowers resistance to manipulation & propaganda

And that aging leads to frontal decline, affecting how seniors vote

You’ll understand why the uncontrolled spread of a virus, well documented to damage the frontal lobes, is encouraged
Why?

Reduced prefrontal cortical function, whether from injury, aging or temp impairment, is associated with decreased critical evaluation, increased impulsivity & greater reliance on emotionally salient narratives, which can increase vulnerability to manipulation & propaganda.
A society’s resistance to propaganda depends on the cognitive health of its population.

If executive function declines at scale, you end up with worse decisions on an individual basis, and weaker collective judgment.

And SARS-CoV-2 is the virus that corrodes executive function.
Read 6 tweets

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