Dr.Sayajirao Gaikwad Profile picture
Aug 24 15 tweets 3 min read Read on X
Most people think Vitamin C = “cold & immunity.”
But deep science shows it’s a frontline nutrient against:
~ Diabetes & obesity
~ Heart disease
~ Cancer biology
~ Constipation & gut health
~ Longevity & slower aging
This is the scientific truth about Vitamin C 🧵🍊👇
What is Vitamin C?
It’s a water-soluble redox molecule.
It acts as both:
1️⃣ Cofactor – activates enzymes for collagen, carnitine, neurotransmitters, hormones
2️⃣ Antioxidant – quenches free radicals & regenerates vitamin E & glutathione

Not optional but this is survival chemistry.
❤️ Heart & Blood Vessels
Vitamin C protects arteries by:
👉Preserving nitric oxide (better BP control)
👉Preventing LDL oxidation (first step in plaque)
👉Strengthening collagen in artery walls (stable vascular “scaffolding”)

Low Vitamin C = higher cardiovascular risk.
🩸 Diabetes & Insulin Resistance
High glucose = oxidative stress → damages blood vessels.
Vitamin C:
👉Reduces glucose-induced endothelial dysfunction
👉Improves insulin sensitivity in low-status people
👉May lower HbA1c modestly

In diabetics, demand for Vitamin C is higher than normal.
🔥 Obesity & Inflammation
Obesity = chronic inflammatory fire.
Vitamin C helps by:
🔸Calming cytokines
🔸Supporting carnitine synthesis (fat oxidation)
🔸Reducing fatigue, improving exercise recovery

Deficiency = harder weight loss & sluggish metabolism.
🧬 Cancer Biology
👉Diets rich in Vitamin C foods → lower cancer risk (observational)
👉Supports DNA stability, immune defense, and collagen barriers
👉High-dose IV Vitamin C is under research not a cure

Food-first Vitamin C remains one of the safest preventive strategies.
💩 Constipation & Gut Health
At higher oral doses, Vitamin C works as a mild osmotic agent → draws water into stool → natural relief.
Also: strengthens gut lining collagen & reduces inflammation.
Commonly used in elderly, obese, or diabetic patients with sluggish bowels.
🧠 Brain & Stress Axis
👉Cofactor for dopamine → norepinephrine
👉Protects neurons from oxidative stress
👉High in adrenal glands → supports stress hormones

Adequacy = sharper cognition + stronger stress resilience.
🦴 Bones, Skin, Healing
Vitamin C = collagen stability.
Benefits:
Stronger bones & joints
Faster wound healing (especially diabetic ulcers)
Skin elasticity & anti-aging

Deficiency = bruising, bleeding gums, slow healing, fragile vessels.
🧪 How Much Do We Need?
RDA: 75–90 mg/day
🔸Optimal: 200–400 mg/day from food
🔸Smokers, obese, diabetics, stressed = need more
🔸Upper safe limit: 2000 mg/day (but avoid >1 g/day long-term if kidney stones risk)
🥦 India-friendly Vitamin C Sources
🔸Amla (200–300 mg per fruit)
🔸Guava (150–200 mg per fruit)
🔸Citrus (orange/mosambi ~70 mg)
🔸Papaya (70–80 mg/cup)
🔸Capsicum, broccoli, cabbage (40–80 mg/cup)

1 guava + 1 amla daily = >300 mg Vitamin C.
⚠️ Who Must Not Ignore Vitamin C
👉Smokers
👉People with diabetes or obesity
👉Heart patients
👉Elderly
👉Chronic wounds / post-surgery patients

These groups show the lowest blood Vitamin C levels & the biggest benefits from correcting intake.
✅ The Takeaway
Vitamin C is NOT a “cold remedy.”
It’s a biological safeguard against:
👉Insulin resistance & obesity inflammation
👉Heart & vascular disease
👉Cancer risk pathways
👉Constipation & gut barrier failure
👉Faster biological aging

Daily intake = metabolic insurance.
💡 Practical hack:
Pair Vitamin C foods with dal, beans, or leafy greens → boosts iron absorption, fights anemia.
Keep tea/coffee 60–90 min away from those meals for max benefit.
If you care about diabetes, obesity, heart health, or cancer prevention:
📌 Save this thread
🔁 Retweet it to help others
🍊 And remember: one guava or one amla daily is more powerful than you think.

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More from @DietDrsayajirao

Aug 22
🌞 One deficiency links to weak bones, obesity, diabetes, mood disorders and India has it at epidemic levels despite free sunlight. Vitamin D is our silent national crisis.
Let’s talk. 🧵
#VitaminD
Multiple Indian studies show 50–90% of people have low Vitamin D across cities, ages, and incomes. This isn’t rare; it’s normalised.
Why this paradox?
Four culprits: indoor life, air pollution (blocks UVB), skin pigmentation (needs longer exposure), and full-coverage clothing.
Read 15 tweets
Aug 20
Most people think fat = extra weight.
Wrong. Fat is an active organ that secretes hormones, drives inflammation, and decides whether you get diabetes, fatty liver, or heart disease.
This is the most detailed science-backed breakdown of fat you’ll read today. 🧵
What is a fat cell (adipocyte)?
A living cell that:
• Stores triglycerides (energy)
• Releases fatty acids during scarcity
• Secretes hormones (adipokines) that control appetite, insulin, inflammation, fertility
Types of fat cells
• White adipocytes (WAT): energy storage; large droplet
• Brown adipocytes (BAT): energy‑burning; many mitochondria; UCP1 for heat
• Beige adipocytes: “convertible” white cells that can turn heat‑producing under cold/exercise
Read 25 tweets
Aug 17
Thyroid: The Master Gland You Can’t Ignore
1 in 3 people may suffer from thyroid dysfunction and most don’t even know it.
Your thyroid is the master regulator of metabolism, energy, weight, mood & fertility.
Here’s the ultimate handbook on thyroid health,science-backed, practical 🧵📖 #Thyroid #MetabolicHealth
What is the thyroid?
The thyroid is a butterfly-shaped gland in your neck.
Despite its tiny size, it controls:
✅ Metabolism (how you burn energy)
✅ Growth & development
✅ Mood & brain health
✅ Reproductive health
✅ Heart, gut & bone function

👉 If thyroid slows down, you slow down. If it speeds up, everything overheats.
Hormones made by thyroid
Your thyroid produces:
🔹 T4 (Thyroxine) – storage form
🔹 T3 (Triiodothyronine) – active form, drives metabolism
🔹 Calcitonin – regulates calcium & bones

💡 Only ~20% of T3 comes directly from thyroid. Rest is converted from T4 in liver, gut & tissues → which is why gut, liver & nutrient health matter.
Read 15 tweets
Aug 15
By your early 20s, you’ve reached your maximum height and built ~90% of your peak bone mass.
That peak will decide your posture, fracture risk, and mobility for the rest of your life.
Here’s the science of bone growth, height potential, and lifelong bone strength 🦴 🧵👇
What is bone?
• 60–70% mineral (hydroxyapatite: calcium + phosphate) → hardness
• 20–30% organic (mostly type-I collagen) → toughness
• ~10% water
This composite makes bone both strong and slightly flexible (key for resisting fractures).
How bones form:
• Intramembranous ossification → flat bones (skull, clavicle) form directly from stem cells
• Endochondral ossification → long bones (femur, tibia) replace a cartilage “model” with bone.
The cartilage zone = growth plate.
Read 22 tweets
Aug 14
Heart disease, stroke, diabetes, cancers :India’s top killers.
Up to 80% are preventable.
Here’s The 2025 Food Pyramid 🥗 backed by global science & designed for the Indian plate to cut your NCD risk in half.
🧵 Read & save this for life ↓
📌 Why a new pyramid?
Old ones focused on calories & food groups, but ignored:
👉Quality of carbs & fats
👉Ultra-processed food (UPF) risks
👉Direct links between diet & NCDs

This one is built to prevent:
✅ Heart disease & stroke
✅ Type 2 diabetes
✅ Many cancers
✅ Chronic kidney disease
Base layer Everyday foundation
👉Vegetables & fruits
👉Whole grains & millets: atta, hand-pounded rice, ragi, bajra, jowar
👉Legumes/pulses: dal, chana, rajma, soy
👉Nuts & seeds: small daily handful
👉Water as your main drink

This mix = more fiber, better blood sugar, lower BP.
Read 13 tweets
Aug 13
Migraine headaches are brutal.
They steal your focus, your sleep, and sometimes entire days of your life.
The good news? Science knows a lot about preventing them.
Here’s your complete, easy-to-use migraine prevention guide,diet, supplements & habits included.🧵👇
#migrainetreatments
#Migraine #Headache
1️⃣ What is a Migraine?
A migraine isn’t “just a headache.”
It’s a neurological condition that causes severe, throbbing pain (often one-sided) with nausea, vomiting, & sensitivity to light/sound.
Attacks can last 4–72 hours and seriously affect quality of life.
2️⃣ Why do Migraines Happen?
Migraines are believed to be triggered by neurovascular changes where brain blood vessels and nerve signals misfire.
The trigeminal nerve releases chemicals → inflammation → pain pathways activate.
Read 12 tweets

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