Here’s a thread on 10 general medicine lessons reinforced in rheumatology 🧵
Tweet 1:
Rheumatology isn’t “super-specialised.”
It’s general medicine… but deeper.
Every principle we learnt in MBBS comes back in rheumatology.
#MedTwitter #Rheumatology @IhabFathiSulima @DrAkhilX @CelestinoGutirr @Janetbirdope @docchennai
Tweet 2
🌡️ Fever of unknown origin
Clues to think beyond infection:
• Rash that comes & goes
• Cytopenias
• Very high ferritin
• Hepatosplenomegaly
• Serositis
Sometimes, fever is inflammation wearing a disguise.
Tweet 3
🫀 Severe hypertension in a 20-something?
Always feel the pulses.
Bruits, unequal BP in arms → large vessel vasculitis.
Sudden crisis in systemic sclerosis → renal emergency.
Not all BP rises are “essential.”
Tweet 4
🧠 Headache that’s new-onset, with jaw pain & raised ESR in >50 yrs = red flag.
Giant Cell Arteritis is a race against blindness.
🧵: The Eye & Rheum: A Clinician’s Guide to Ocular Manifestations
Tweet 1:
1/10 👁️ The eye isn’t just the window to the soul—in medicine, it’s a window to systemic disease. Many rheumatic conditions write their first, or most severe, chapters on the ocular surface. A thread for clinicians on the critical link between Rheumatology & Ophthalmology. #RheumTwitter #OphthoTwitter #MedEd @IhabFathiSulima @Janetbirdope @DrAkhilX @ACRheum @RheumNow
Tweet 2: Anatomy Primer
2/10 Before we dive in, let’s map the battlefield. Key structures where rheumatology makes its mark:
•Uvea: The pigmented middle layer (iris, ciliary body, choroid).
•Sclera: The tough, white outer layer.
•Cornea: The transparent front.
•Lacrimal Glands: The tear producers.
Tweet 3: Anterior Uveitis & Spondyloarthritis
3/10 The Classic Duo: Anterior Uveitis & Spondyloarthritis (SpA). A patient with acute, unilateral eye pain, redness, & photophobia? Think SpA, especially if they are HLA-B27+. This is often the first clue leading to an AxSpA diagnosis. #Uveitis #AnkylosingSpondylitis
🧵 Drug vs Disease — When Side Effects Mimic the Diagnosis👇
Is it the disease—or the drug? Many “flares” are actually medication effects. Here’s a clinic-ready guide to the most common drug–disease confusions, what to check, and how to pivot fast. Save and share. #MedTwitter #RheumTwitter #FOAMed #IMTwitter #PrimaryCare #PatientSafety @IhabFathiSulima @DrAkhilX @Janetbirdope
Post 1
Big idea
Before escalating therapy, ask: could the medication be causing or unmasking the symptom? Use this checklist: timing vs start/dose change, dose–response, dechallenge/rechallenge, and alternative explanations.
Post 2
NSAIDs vs kidney/pressure
•Looks like: edema, rising creatinine, “worsening gout/OA pain”
•Could be: NSAID nephrotoxicity or hypertension
•Check: creatinine/eGFR, BP, volume status; step down NSAID, switch to topical or COX-2 cautiously; renal-safe analgesia plan.
🧵 Steroid Stewardship & Safe Tapering: A Practical Playbook👇
For clinicians across primary care, rheumatology, IM, EM, and dermatology
Steroids help fast—but harm fast without a plan. Here’s a concise, clinic-ready playbook: when to start, how to taper, who needs bone/GI/infection protection, and when to escalate. Save this thread, share with teams, and use it tomorrow. #RheumTwitter #MedTwitter #FOAMed #PatientSafety #PrimaryCare #IMTwitter
@IhabFathiSulima @DrAkhilX @ACRheum @IRAeNewsLetter @DurgaPrasannaM1 @CelestinoGutirr @NeuroSjogrens @nirmalregency @Janetbirdope @Lupusreference #MedTwitter #Rheumatology #RheumTwitter #PrimaryCare #GP #IMTwitter
Post 1
Steroids help fast—but harm fast if misused. Goals: shortest duration, lowest dose, clear taper, bone protection, and an exit plan. Save for clinic.
#MedTwitter #RheumTwitter #FOAMed #GP #PrimaryCare
Post 2
Before starting prednisone:
•Confirm inflammatory indication (not purely mechanical pain)
•Baseline: BP, weight, glucose, ±lipids; vaccine status
•Agree on dose, duration, taper, monitoring, rescue plan
#PatientSafety #ClinicalTips #IMTwitter
Clinical Rheumatology Thread for Busy GPs:
Post 1
Early inflammatory arthritis(IA): the 3–3–3 rule
•Onset ≤3 months
•Morning stiffness ≥30–60 minutes
•≥3 swollen joints (MCP/MTP common)
If present, manage as IA: urgent rheum referral; NSAIDs if no contraindications.
@IhabFathiSulima @DrAkhilX @DurgaPrasannaM1 @Janetbirdope @ACRheum @RheumNow @Amansharmapgi @12VRavindran #MedTwitter #Rheumatology
Post 2
Red flags over patterns
Screen for: systemic (fever, weight loss, night sweats), vascular (new headache >50y, jaw/limb claudication), neuro/renal (hematuria, neuropathy).
Any present → same-week labs (CBC, ESR/CRP, creatinine, urinalysis) and escalate.
Post 3
Morning stiffness as a clue
60–90 min: inflammatory (RA, PMR, axial SpA)
•<30 min: mechanical (OA)
Pair with distribution: small joints=RA; spine/SI=axSpA; DIPs=PsA/OA.
🧵 2025 AHA Hypertension Guidelines: Changes & New Updates 1/ The 2025 AHA/ACC hypertension guideline replaces the 2017 version with key, evidence-driven changes. Here are the must-know updates for your clinical practice.
@IhabFathiSulima @DrAkhilX @TrackYourHeart @sumersethi @Mahmoud33986639 @latchumanadhas #MedTwitter
2/ PREVENT Risk Equation Now Central
All therapy decisions now use the PREVENT risk score (not pooled cohort equations). The 10-year CVD risk threshold to start medication is now ≥7.5%—so more patients, especially with moderate risk, will get earlier treatment.
3/ Initiation of Therapy at Lower Thresholds
Stage 1 hypertension (130–139/80–89 mm Hg):
•If CVD, CKD, diabetes, or PREVENT risk ≥7.5%, start antihypertensive immediately.
•If PREVENT risk <7.5%: start with lifestyle changes for 3–6 months. If BP stays ≥130/80, add medication.
This expands eligibility —more aggressive than 2017.
🧵 Hematological Manifestations in Autoimmune Diseases—2025 Clinical Update 1/ Blood disorders are common in autoimmune diseases and may be the first clue. Timely recognition can be lifesaving. Here’s a crisp clinical thread every practitioner should bookmark.
@IhabFathiSulima @DrAkhilX @CelestinoGutirr @HematologyAdv @EHA_Hematology #MedTwitter #Rheumatology
2/ 🦋 Lupus (SLE):
•Anemia (iron-deficiency, hemolytic, chronic disease, drug-induced)
•Lymphopenia
•Thrombocytopenia (may be severe)
All correlate with disease activity and need close monitoring.
3/ 🤲 Rheumatoid Arthritis (RA):
•Anemia of chronic disease
•Felty’s syndrome: RA + big spleen + neutropenia
•Drug-induced cytopenias (MTX, biologics)
•Blood markers (Hb, NLR) can predict flare/remission.