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Aug 29 • 9 tweets • 5 min read • Read on X
Cortisol can be completely stopped with a simple & cheap supplement, according to a fascinating study.

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This study was published in 2016, evaluating the anti-stress properties of L-THEANINE.

This is an amino acid found naturally in green tea.

People were given either a mix of:

āž  L-theanine (200 mg)
āž  L-alpha glycerylphosphorylcholine (alpha GPC; 25 mg),
āž  Phosphatidylserine (1 mg)
āž  Micronized chamomile (10 mg)

Or placebo, alongside a cognitive assessment.

While the drink did have these other ingredients, they are far below (<1-10%) their typical dosing - so their impacts were likely small or negligible.

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People consuming the L-Theanine drink reported markedly lower stress within the first hour.

They actually felt less stressed with the L-theanine, than they did prior, even though they were taking this assessment.

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L-Theanine also completely prevented the rise in cortisol from the assessment.

While those without the L-theanine showed higher cortisol 3 hours after the test,

those with the L-theanine had LOWER cortisol.

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Those on L-Theanine also had improved cognitive function.

While not statistically significant, there was a clear trend for improvements on the MTF - an assessment of:

ā—‡ Working memory
ā—‡ Attention
ā—‡ Processing speed
ā—‡ Numerical reasoning
ā—‡ Executive function

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L-Theanine also induced greater alpha waves in the brain.

This type of brain wave is associated with more controlled activity, and less stress / scatterbrained thoughts.

It is a signal of a relaxed alertness.

This was especially apparent in people with anxiety.

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Why is L-Theanine so good for stress / cognitive function?

Theanine is structurally similar to the amino acid glutamate, which is a prominent neurotransmitter in the brain.

Glutamate is the primary "excitatory" neurotransmitter, and thus in excess can contribute to stress, OCD, ADHD, anxiety, even depression and other conditions.

Excess glutamate will make you feel wired and scatterbrained.

We do need some glutamate, though. It helps the growth / proliferation of brain cells, it can stimulate dopamine production, and is necessary for clarity / alertness.

Theanine acts primarily by inhibiting the release of glutamate from neurons, thus having a calming effect.

It can actually stimulate the some of the glutamate receptors, though, reaping the dopamine + neurogenesis benefits while keeping us calm.

Additionally, theanine boosts the amounts of GABA - our primary inhibitory neurotransmitter.

GABA is the opposite of glutamate, it'll chill you out, result in deep sleep, and crush anxiety.

Theanine also can raise the levels of glycine in the brain, another neurotransmitter involved in both inhibition and relaxation, as well as the glutamate-mediated formation of new brain cells.

Theanine ALSO has antioxidant and anti-inflammatory effects.

It makes sense why theanine is so effective and safe for so many different things - it really can help to balance things out in the brain, without acting non-discriminately like a drug.

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This is the L-Theanine product we use personally + with clients
collabs.shop/8besln
While theanine is great for lowering stress and improving cognitive function, it's best as a part of a more comprehensive plan tailored to your health goals.

Book a free call with us here and we can help you get there:
go.prism.miami/consultation

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More from @Outdoctrination

Aug 28
Vitamin B1 (thiamine) megadosing can massively reduce fatigue, in many cases reversing it entirely.

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This study was a small pilot study conducted about a decade ago.

Anywhere from 600-1500 mg of B1 was used, depending on the weight of the patient.

The results were stunning.

10/12 patients had a complete reversal of fatigue.

The other two saw reductions by 50% and 66%.

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What was stunning about this study was that these people did not have thiamine (B1) deficiency,

yet they responded to thiamine megadoses as if they were.

This is likely because measuring the amount of B1 or its active metabolite, TPP, is not sufficient to tell if someone gets enough of it into their cells, where it exerts its effects.

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Read 23 tweets
Aug 26
A new study shows vitamin E can reverse fibrosis, inflammation and fat buildup in the liver.

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This study was published in Cell Medicine earlier this year.

Many studies have already shown that vitamin E has protective effects for the liver,

but this was the longest one to date (96 weeks) investigating this low of a dose of vitamin E - 300 mg of alpha tocopherol (450 IU) per day.

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People receiving the vitamin E had visible improvements in their liver condition.

29.3% of people showed improvement in liver histology (>2X as good as placebo)

25.9% showed reductions in fibrosis - the scarring of the liver (>60% better than placebo)

Reducing fibrosis is HUGE - this is the most dangerous and irreversible part of these conditions.

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Read 9 tweets
Aug 26
Red light therapy reverses all signs of skin aging, as shown in a recent study.

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This study used red light therapy 2x a week for 3 months.

āž” 12 min / session
āž” 630 nm (red light wavelength)
āž” 15.6 J/cm^2 (power density)

with the Skin Light Dior Ɨ Lucibel mask.

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Wrinkles were substantially decreased with the red light.

After 1 month of use, crow's feet (wrinkles by the eyes) decreased in depth by over 15%.

After 3, they decreased by over 38%.

The more it was used, the less wrinkles.

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Read 11 tweets
Aug 25
A new landmark study has shown that eating meat is actually protective against cancer.

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This study was published last month in the journal of Applied Physiology, Nutrition, and Metabolism.

There has been a lot of noise around the idea that animal protein can increase cancer and death risk, as one highly publicized studies from the 2014 suggested.

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They used data from the Third National Health and Nutrition Examination Survey (NHANES III).

This dataset has people track their food, and also ensures its accuracy by administering 24 hour dietary recall surveys.

Unlike the previous 2014 study, they used the multivariate Markov Chain Monte Carlo (MCMC) method, which uses multiple 24 hour dietary recalls to better estimate the USUAL intake of people.

Previously, only single 24 hour dietary recalls were used, which is considerably less reliable since it's only measuring one day.

Thus, this study is considered to be the most statistically rigorous to date.

(3/7)
Read 7 tweets
Aug 22
A disturbing new study shows that colon cancer tumors concentrate microplastics, and that nearly every colon tissue analyzed contains them.

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Microplastics are tiny breakdown products of larger plastics, degraded by microbes, heat and other processes.

We are becoming progressively exposed to them in recent years.

This study was published this month, reviewing studies that looked at samples of:

āž„ Colon cancer tumors
āž„ Colon tissue from non tumor regions in cancer patients
āž„ Colon tissue from people without cancer

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They found that the microplastics in the colon samples had a size of 0.1–1.6 mm.

For reference, a grain of sand is around 0.1 mm, and a sesame seed is about 1.6 mm.

One study found these fragments in all colon tissues, with around 28 fragments per gram of tissue.

They also stated that it's "estimated that humans ingest between 39,000 and 52,000 particles per year"

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Read 8 tweets
Aug 22
A study shows that 2 cups of orange juice completely reverses many of the negative effects of a McDonald's meal.

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This study was done in the American Journal of Clinical Nutrition.

They gave people either egg-muffin and sausage-muffin sandwiches and 2 hash-browns with:

āž„ 75g straight glucose
āž„ Water
āž„ 2.5 cups of OJ

The OJ was not from concentrate, so pretty fresh.

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Strikingly, having the orange juice alongside the meal did NOT raise blood sugar AT ALL.

Having the meal alongside water or glucose did result in an elevation.

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Read 11 tweets

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