Dr. Chris Chappel Profile picture
Sep 7, 2025 16 tweets 5 min read Read on X
3 in 4 women under 45 are in perimenopause... and have no clue.

Most think it’s just aging.

But it’s a silent hormone crash causing:
• Sleepless nights
• Weight gain
• Anxiety

Here’s how to spot it early (and balance your hormones naturally): 🧵
Perimenopause can start up to 10 years before menopause.

That means it often begins much earlier than most expect.

Women in their 30s and 40s may already be experiencing hormone shifts…

Without being told what’s happening.

(watch this video to spot the signs yourself)
The biggest problem?

Most women think they’re “too young” for hormonal changes.

Doctors often dismiss symptoms as stress or lifestyle.

The result: years of silent suffering. Image
Hormones act like your body’s communication system.

When estrogen and progesterone fluctuate wildly, the whole system feels off.

That’s why symptoms aren’t “just hormonal,” they touch mood, sleep, energy, and metabolism.

(this video shows 5 common signs of low progesterone)
Common early signs include:

• Unexplained weight gain
• Irregular cycles
• Poor sleep or night sweats
• Mood swings or anxiety
• Brain fog
• Lower libido

If these sound familiar, it may not be “stress.” Image
Weight gain in perimenopause isn’t just cosmetic.

Estrogen imbalance shifts fat storage to the belly...

Raising the risk of insulin resistance, diabetes, and heart disease.

It’s not vanity. It’s health. Image
Sleep disruption is another overlooked sign.

Estrogen helps regulate serotonin and melatonin.

When it drops, deep sleep vanishes.

This leads to fatigue, cravings, and worsened mood swings. Image
Anxiety and mood swings in perimenopause aren’t “just in your head.”

Estrogen regulates GABA → your calming neurotransmitter

When levels swing, the nervous system feels like it’s stuck in fight-or-flight

Even small stressors feel overwhelming.

(watch the science behind it)
Brain fog can be one of the most disabling signs.

Estrogen shifts affect:
• Blood flow to the brain
• Glucose delivery to neurons
• Neurotransmitter balance

The result?
Memory lapses, poor focus, and “losing your words” mid-sentence. Image
Perimenopause isn’t a “phase” you breeze through.

It can last 4–10 years.

That’s nearly a decade where fluctuating hormones quietly raise risks of:

• Belly fat
• Fatigue
• Mood disorders
• Diabetes & heart disease Image
Here’s the key:

Perimenopause is not a disease.

It’s a natural transition, but without support, it can increase risks of diabetes, heart disease, osteoporosis, and mental health struggles.
The early signs women think are “just aging” like weight gain, poor sleep, mood swings, are often perimenopause.

Spotting them early gives you the chance to protect your hormones, energy, and long-term health.
I’ve helped hundreds of women balance their hormones, reclaim energy, and prevent long-term complications of perimenopause.

Without crash diets, pills, or quick fixes.

DM me “HORMONES” and I’ll share how my program helps women restore balance, clarity, and confidence.
Follow @ChappelDr for more health insights.

Repost the quote below if you found this helpful.

And comment down below:

What are you struggling with most? 👇
Disclaimer:

This content is for informational purposes only and does not constitute personalized medical advice.

Consult your healthcare provider before making changes to your health regimen.
Sources:

PMID: 37755656
PMID: 40264725
PMID: 40094961
PMID: 31942151
PMID: 23770320

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More from @ChappelDr

Oct 15, 2025
The #1 health issue in 2025:

Insulin resistance.

Without control, you stay exhausted, inflamed, and trapped in a cycle of energy crashes and stubborn fat gain.

After 10 years as functional MD, here’s how to fix your insulin (before it turns into chronic disease): 🧵 Image
Most people think insulin resistance is just about blood sugar.

It’s not.

It’s a full-body metabolic breakdown hiding in plain sight…

and the signs show up years before blood sugar ever does.
What insulin actually does = shuttle nutrients into your cells.

When it works:
• More muscle
• Better recovery
• Stable energy

When it fails → your body gets stuck in a destructive loop most doctors never explain. Image
Read 17 tweets
Sep 19, 2025
As a functional MD, I’ll be honest:

If your metabolism is wrecked…

Clean eating and 10k steps a day won’t cut it.

Here is what actually resets your metabolism (even after years of sugar): 🧵 Image
Image
Blood sugar spikes wreck metabolism.

Most people think metabolism is just “calories in vs. calories out.”

It’s not.

Every blood sugar spike:
• Floods insulin
• Fuels inflammation
• Crashes cortisol

Over time → cells stop responding. Energy tanks. Fat won’t budge. Image
Wear a CGM and you’ll see it instantly:

• Protein before carbs = smaller spikes
• Snacking all day = insulin never rests
• Oatmeal in the morning = Often worse than dessert.

Stabilize blood sugar → energy returns, brain fog fades, fat starts burning. Image
Read 21 tweets
Aug 24, 2025
Diabetes doesn’t start overnight.

It builds silently for 10+ years before diagnosis.

The worst part? Millions already have it and have no clue.

It drains your energy, wrecks metabolism, and stores fat.

Here’s what's happening (and how to spot it early): 🧵 Image
1. How diabetes really begins

Type 2 diabetes starts as insulin resistance.

Your cells stop responding to insulin.

Sugar stays in your blood instead of being used for fuel.

This silent shift is the first step toward diabetes.
2. The chain reaction inside your body

When blood sugar stays high:

• Pancreas pumps out more insulin
• Fat storage (especially belly fat) increases
• Energy crashes hit after meals
• Inflammation spreads silently Image
Read 16 tweets
Aug 10, 2025
Aging doesn’t just give you wrinkles.

It clogs your arteries, weakens your brain, and steals decades from your life.

Here are 9 science-backed ways to reverse your biological clock starting today: 🧵

1. Eat dinner for breakfast.
Eat most of your calories early in the day.

Your body handles calories best in the morning.

Big meals early = better insulin control, lower inflammation, slower aging.

Late-night eating does the opposite—it silently speeds up your biological clock. Image
2. Build strength.

Muscle loss is the #1 sign of aging.
Lift weights 2–3 times a week.

Focus on compound moves:
• Squats
• Deadlifts
• Push-ups
• Rows

See why muscles are important the more you age:
Read 15 tweets
Aug 8, 2025
The most dangerous, oddly glorified, yet overlooked problem in the world:

Chronic inflammation.

It slowly kills your immune defenses and sets you up for disease.

Here are 10 ways to reverse it naturally: 🧵

1. Use full-fat dairy
We’ve been told “fatty dairy = bad for health.”

But studies show yogurt, milk, and cheese can lower CRP and other inflammation markers.

Especially the fermented varieties.

Skip the “low-fat” labels.
Nature’s version is often the real medicine. Image
2. Add anti-inflammatory spices.

• Turmeric
• Ginger
• Cinnamon
• Cloves
• Black pepper

These switch off the “alarm signals” that keep your body inflamed.

See the best 2 spices to use and their benefits:
Read 16 tweets
Aug 2, 2025
If your metabolism is broken, you won’t lose fat... you’ll store it.

It triggers belly fat, sugar cravings, and fast exhaustion.

Here are 9 science-backed ways to reset your metabolism and burn fat for good: 🧵

1. Ditch morning coffee.
But why?

Caffeine can spike cortisol on an empty stomach.

Pair that with dehydration?
Your metabolism gets throttled before breakfast.

Start your day with 16–20 oz of water + a pinch of salt. Then coffee.

Watch how coffee can increase stress and slow metabolism:
2. Stop starving yourself.

Metabolism isn’t just about calories—it’s about hormones.

Chronic under-eating slows thyroid output, drops leptin, and raises cortisol.

Eat enough to fuel your body, especially if you’re active. Image
Read 15 tweets

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